H2S, Polysulfides and Antioxidases in Supporting Life: From Bacteria to Humans
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (20 November 2024) | Viewed by 216
Special Issue Editor
Interests: biochemistry; clinical bichemistry; enzymology; molucular environmental medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The ancient atmosphere of Earth was still anoxic and characterized by reducing conditions when living organisms emerged approximately a billion years ago. After the evolution of cyanobacteria, the oxygen concentration of the air increased from the beginning of the Cambrian period and gradually stabilized at around 21%. Mammals emerged approximately 250 million years ago and utilized this abundant oxygen.
Therefore, oxygen concentration became a critical factor in biological evolution. Along the evolutionary journey, organisms evolved intricate defense mechanisms involving antioxidant molecules. These include sulfur-containing compounds and a diverse array of enzymes and proteins known as antioxidases. Antioxidases, such as catalase, superoxide dismutase, and various peroxidases, play a crucial role in combating oxidative stress by scavenging free radicals and repairing cellular damage.
In this Special Issue, we aim to further the understanding of how sulfur-containing compounds (such as H2S and polysulfides) and antioxidases have emerged, evolved, and supported living organisms, from bacteria to humans, throughout evolution.
Prof. Dr. Noriyuki Nagahara
Guest Editor
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Keywords
- H2S
- polysulfides
- antioxidases
- bacteria
- human
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