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Antioxidants
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The Role of Antioxidants in Enhancing Training Adaptation, Exercise Performance,...
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The Role of Antioxidants in Enhancing Training Adaptation, Exercise Performance, and Post-exercise Recovery

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 1328

Special Issue Editors

Dr. Sihui Ma

E-Mail Website
Guest Editor
Faculty of Human Sciences, Waseda University, Tokorozawa 359-1192, Japan
Interests: macronutrients and health; inflammation; exercise metabolism; exercise mimetics; cross talk; ketogenic diet
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Katsuhiko Suzuki

E-Mail Website
Guest Editor
Faculty of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan
Interests: immunology; inflammation; muscle damage; cytokine; leukocyte; oxidative stress
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the role of antioxidants in exercise has become a topic of great interest among researchers and athletes alike. While reactive oxygen species (ROS) generated during exercise were once considered detrimental, current evidence suggests that moderate levels of ROS play a crucial role in inducing beneficial adaptations to training. Antioxidants, known for their ability to neutralize ROS, have been studied for their potential to modulate the redox balance and influence exercise-related outcomes.

This Special Issue aims to provide a comprehensive overview of the multifaceted role of antioxidants in exercise science. We welcome contributions that explore the complex interplay between antioxidants, ROS signaling, and exercise adaptations.

Topics of interest include, but are not limited to, the following:

  1. The impact of antioxidants on the cellular signaling pathways involved in muscle hypertrophy, mitochondrial biogenesis, and endurance adaptations.
  2. The effects of antioxidant supplementation on exercise performance, fatigue, and recovery.
  3. The role of endogenous antioxidant systems in response to acute and chronic exercise.
  4. The potential benefits and drawbacks of antioxidant supplementation in different athletic populations and training contexts.
  5. Novel antioxidant compounds and their applications to exercise nutrition.
  6. Methodological considerations in assessing oxidative stress and antioxidant status in exercise studies.

By bringing together cutting-edge research on antioxidants and exercise, this Special Issue aims to advance our understanding of how to optimize training adaptations, enhance performance, and facilitate post-exercise recovery while maintaining a healthy redox balance. We encourage contributions from diverse disciplines, including exercise physiology, nutrition, biochemistry, and sports medicine, to foster a multidisciplinary approach to this exciting field of research.

Dr. Sihui Ma
Prof. Dr. Katsuhiko Suzuki
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • exercise science
  • antioxidants
  • ROS
  • sports
  • exercise physiology

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Published Papers (1 paper)

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Research

18 pages, 3921 KiB  
Article
8-Week Kaempferia parviflora Extract Administration Improves Submaximal Exercise Capacity in Mice by Enhancing Skeletal Muscle Antioxidant Gene Expression and Plasma Antioxidant Capacity
by Jiapeng Huang, Yishan Tong, Shuo Wang, Takashi Tagawa, Yasuhiro Seki, Sihui Ma, Ziwei Zhang, Tiehan Cao, Haruki Kobori and Katsuhiko Suzuki
Antioxidants 2024, 13(9), 1147; https://doi.org/10.3390/antiox13091147 - 23 Sep 2024
Viewed by 956
Abstract
Black ginger (Kaempferia parviflora) extract (KPE) is extracted from a ginger family plant grown in Thailand. The polyphenolic components have potential antioxidant effects and have been reported to enhance exercise performance. However, the impact of long-term KPE administration combined with long-term [...] Read more.
Black ginger (Kaempferia parviflora) extract (KPE) is extracted from a ginger family plant grown in Thailand. The polyphenolic components have potential antioxidant effects and have been reported to enhance exercise performance. However, the impact of long-term KPE administration combined with long-term training on the endurance exercise performance of healthy individuals has not been fully studied. In this study, a healthy mouse model was used to investigate the effects of 8 weeks KPE administration and voluntary wheel running on the submaximal endurance exercise capacity and its mechanism. The results showed that 8 weeks of KPE administration significantly enhanced the submaximal endurance exercise capacity of mice and extended the daily voluntary wheel running distance. By measuring oxidative stress markers in plasma and the mRNA expression of antioxidant genes in skeletal muscle, we found that KPE significantly increased plasma antioxidant levels and activated the Nrf2 (Nuclear factor erythroid 2-related factor 2)/ARE (Antioxidant Response Element) pathway and its downstream antioxidant genes expression in skeletal muscle. These results suggest that KPE may enhance the antioxidant capacity of plasma and skeletal muscle by activating the Nrf2-ARE-centered antioxidant pathway, thereby increasing the daily running distance and improving the submaximal endurance exercise capacity of mice. Full article
(This article belongs to the Special Issue The Role of Antioxidants in Enhancing Training Adaptation, Exercise Performance, and Post-exercise Recovery)
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