Plant Polyphenols in Cancer Chemoprevention
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (30 January 2017) | Viewed by 10423
Special Issue Editor
Interests: dietary antioxidants; phytochemicals; polyphenols; flavonoids and their derivatives; chemoprevention; molecular mechanisms of action; DNA damage signaling and DNA repair; postbiotics of polyphenols
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Carcinogenesis is a multistage process that involves a series of events comprising genetic and epigenetic changes leading to the initiation, promotion and progression of cancer. Chemoprevention is referred to as the use of nontoxic natural compounds, synthetic chemicals or their combinations to intervene in multistage carcinogenesis. Chemoprevention through diet modification, i.e., increased consumption of plant-based food, has emerged as a very promising and realistic approach to reduce the risk of cancer. Polyphenols are naturally occurring secondary metabolites that are ubiquitous in plant-based food such as fruits, vegetables, teas, as well as in most medicinal plants. Over 30,000 polyphenols have been characterized over the last few decades. Polyphenols comprise of several sub-classes including flavonoids (flavonols, flavan-3-ols, anthocyanins, flavonones, flavones, isoflavones and proanthocyanidins), lignans, xanthones, stilbenes, and curcuminoids. Identification of most efficacious plant polyphenols and understanding of the molecular basis of how polyphenols contribute to the chemoprevention including protection against DNA damage caused by various carcinogenic factors is important in developing effective cancer chemopreventive strategies.
This Special Issue will publish both reviews and original research papers on the role of plant polyphenols in cancer chemoprevention. The molecular mechanisms associated with polyphenols as cancer prevention agents, as well as anti-cancer therapeutic effects of polyphenols will also be included.
Prof. H.P. Vasantha Rupasinghe
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Polyphenols
- Flavonoids
- Cancer
- Antioxidants
- Chemoprevention
- Cytoprotection
- Carcinogenesis
- Detoxification of procarcinogens
- Oxidative DNA damage
- DNA damage signaling
- DNA repair
- Cell cycle checkpoint arrest
- Apoptosis
- Mechanisms of action
- Structure-function relationship
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
