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Audiology Research
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Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment
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Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment

A special issue of Audiology Research (ISSN 2039-4349).

Deadline for manuscript submissions: 30 April 2025 | Viewed by 8697

Special Issue Editor

Dr. George K. Psillas

E-Mail Website
Guest Editor
1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, 546 36 Thessaloniki, Greece
Interests: hearing rehabilitation; middle and inner ear; ear surgery; cochlear implantation; auditory brainstem responses; facial nerve electrophysiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Hearing loss represents one of the most wide-ranging disabilities, affecting more than 5% of the world’s population. Different types of hearing loss, including conductive and sensorineural hearing loss, may lead to serious hearing impairments in children and adults. Multiple causes may be involved in the aetiopathogenesis of hearing loss, depending on the different biologic mechanisms, including congenital and autoimmune. Diagnosis and management continue to be a challenge for hearing disorders such as chronic otitis media, otosclerosis, cholesteatoma, congenital or acquired sensorineural hearing loss, sudden sensorineural or metabolic hearing loss, and otogenic facial palsy. Electrophysiology and neuroscience approaches are needed in order to better elucidate the diagnostic dilemmas in the field of otology and neurotology. New treatment options will be discussed to improve potential methods of hearing restoration.

We especially encourage submissions concerning hearing aids, cochlear/vestibular/auditory brainstem implantation, middle ear surgery, and stapedotomy:

  • age-related hearing loss
  • genes associated with hearing loss
  • speech perception testings
  • pathophysiologic patterns for hearing loss
  • neuroimaging for inner ear
  • electrophysiologic evaluation of hearing loss
  • surgery for hearing loss / cophosis

Dr. George K. Psillas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Audiology Research is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • genetics
  • speech perception
  • conductive hearing loss
  • sensorineural hearing loss
  • neuroimaging
  • electrophysiology
  • cochlear implants

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Published Papers (6 papers)

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Research

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15 pages, 2766 KiB  
Article
Middle Ear Active Implant Indications, Comparative Audiometric Results from Different Approaches, and Coupling with the Vibrant Soundbridge®: A Single Center Experience over More Than 20 Years
by Joan Lorente-Piera, Raquel Manrique-Huarte, Janaina P. Lima, Diego Calavia and Manuel Manrique
Audiol. Res. 2024, 14(4), 721-735; https://doi.org/10.3390/audiolres14040061 - 21 Aug 2024
Viewed by 685
Abstract
Background: Middle ear active implants, such as the Vibrant Soundbridge (VSB), offer an alternative to reconstructive surgery and other implantable hearing aid systems for patients with conductive, mixed, or sensorineural hearing loss. The primary objective of this work is to describe the auditory [...] Read more.
Background: Middle ear active implants, such as the Vibrant Soundbridge (VSB), offer an alternative to reconstructive surgery and other implantable hearing aid systems for patients with conductive, mixed, or sensorineural hearing loss. The primary objective of this work is to describe the auditory results obtained with VSB in our patient cohort, measuring the auditory gain in terms of average tonal thresholds and spoken word discrimination at 65 dB. Secondly, auditory gain differences between different types of hearing loss, coupling to the ossicular chain compared to round and oval windows, and the impact of open versus more conservative surgical approaches, were analyzed. Methods: A cross-sectional observational study, with retrospective data collection, was conducted at a tertiary care center. Clinical and audiometric data pre- and post-implantation were included, from patients who underwent VSB device placement surgery between 2001 and 2024. Results: 55 patients with an average age of 62.58 ± 17.83 years and a slight preference in terms of the female gender (52.72%) were included in the study. The average gain in the PTA for all types of hearing loss was 41.56 ± 22.63 dB, while for sensorineural hearing loss (SNHL) the gain was 31.04 ± 8.80 dB. For mixed-conductive hearing loss (C-MHL) a gain of 42.96 ± 17.70 was achieved, notably, in terms of absolute values, at frequencies of 4000 and 6000 Hz, with gains reaching 49.25 ± 20.26 dB at 4 K and 51.16 ± 17.48 dB at 6 K. In terms of spoken word discrimination, for all types of hearing loss, an improvement of 75.20 ± 10.11% was achieved. However, patients with C-MHL exhibited an approximately 13% higher gain compared to those with SNHL (69.32 ± 24.58% vs. 57.79 ± 15.28%). No significant differences in auditory gain were found between open and closed surgical techniques, nor in the proportion of adverse effects, when comparing one technique with the other. Conclusions: The VSB is effective in improving hearing in patients with mixed, conductive, and sensorineural hearing loss, with significant gains at high frequencies, especially through the round window membrane approach. The choice of surgical technique should consider the patient’s anatomical characteristics and specific needs in order to optimize auditory outcomes and minimize postoperative complications. Full article
(This article belongs to the Special Issue Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment)
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15 pages, 1231 KiB  
Article
Preliminary Validation of the Children’s Auditory Performance Scale (CHAPS) and the Auditory Processing Domain Questionnaire (APDQ) in Greek Cypriot Children
by Konstantinos Drosos, Dionysios Tafiadis, Louiza Voniati, Alexandra Papanicolaou and Chryssoula Thodi
Audiol. Res. 2024, 14(4), 625-639; https://doi.org/10.3390/audiolres14040053 - 15 Jul 2024
Viewed by 1428
Abstract
Background: Identification of auditory processing disorders is achieved using questionnaires along with linguistic, non-linguistic, and auditory processing tests. Notably, the questionnaires “Children’s Auditory Performance Scale” (CHAPS) and “Auditory Processing Domain Questionnaire” (APDQ) are widely recognized and used. The current study investigated the psychometric [...] Read more.
Background: Identification of auditory processing disorders is achieved using questionnaires along with linguistic, non-linguistic, and auditory processing tests. Notably, the questionnaires “Children’s Auditory Performance Scale” (CHAPS) and “Auditory Processing Domain Questionnaire” (APDQ) are widely recognized and used. The current study investigated the psychometric properties of the CHAPS and APDQ in Greek Cypriot children. Methods: The CHAPS and APDQ questionnaires were completed by parents of 40 Greek Cypriot children, 16 typically developing (TD) children, and 24 children with a history of Speech Sound Disorders (SSDs). Results: There were significant differences between the two groups on both questionnaires. Cronbach’s alpha was calculated at α = 0.922 for the CHAPS total score and α = 0.926 for the APDQ total score. The Receiver Operating Curve (ROC) analysis provided a cut-off point equal to −0.30 (AUC 0.849, p < 0.001) for CHAPS and a cut-off point equal to 90.00 (AUC 0.820, p < 0.001) for APDQ. Significant positive Spearman ρ correlations were observed between the CHAPS and APDQ (ρ = 0.639, p = 0.001). Conclusions: The CHAPS and APDQ can identify distinct auditory processing characteristics between in children with SSDs and TD children. Full article
(This article belongs to the Special Issue Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment)
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9 pages, 231 KiB  
Article
Assessing the Effectiveness of Different Hyperbaric Oxygen Treatment Methods in Patients with Sudden Sensorineural Hearing Loss
by Paweł Rozbicki, Jacek Usowski, Sandra Krzywdzińska, Dariusz Jurkiewicz and Jacek Siewiera
Audiol. Res. 2024, 14(2), 333-341; https://doi.org/10.3390/audiolres14020029 - 29 Mar 2024
Cited by 2 | Viewed by 1468
Abstract
Introduction: Hyperbaric oxygen therapy (HBOT) is one of the treatment methods in patients with sudden sensorineural hearing loss (SSNHL). It is recommended as an elective treatment in patients undergoing steroid therapy. According to current scientific reports, HBOT should be implemented within two weeks [...] Read more.
Introduction: Hyperbaric oxygen therapy (HBOT) is one of the treatment methods in patients with sudden sensorineural hearing loss (SSNHL). It is recommended as an elective treatment in patients undergoing steroid therapy. According to current scientific reports, HBOT should be implemented within two weeks after the first symptoms. However, as far as the profile of HBOT is concerned, there are no straightforward recommendations. Methods: The data obtained from the medical records of 218 patients undergoing HBOT for SSNHL at the Military Institute of Medicine—National Research Institute were analyzed statistically for the impact of the duration and the delay in implementing HBOT on the end results of pure-tone audiometry (PTA). Results: A statistically significant hearing improvement in patients undergoing more than 15 cycles of HBOT was detected at all frequencies except for 1500 Hz; in the group reporting for treatment with a delay of more than 10 days, hearing improvement was statistically unsignificant at frequencies of 1500, 3000, and 4000 Hz. Conclusions: The statistical analysis showed that the urgent onset of HBOT could be a significant factor in the therapy of SSNHL. Full article
(This article belongs to the Special Issue Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment)
11 pages, 1136 KiB  
Article
Over-the-Counter (OTC) Hearing Aid Availability across the Spectrum of Human Skin Colors
by Shade Avery Kirjava and Sam Jones Faulkner
Audiol. Res. 2024, 14(2), 293-303; https://doi.org/10.3390/audiolres14020026 - 12 Mar 2024
Viewed by 1626
Abstract
Background: Over-the-counter (OTC) hearing aids were recently approved for sale in the United States. Research has shown that consumers prefer hearing devices that match their skin color because these devices are less noticeable. Colorism is discrimination against individuals with relatively darker skin that [...] Read more.
Background: Over-the-counter (OTC) hearing aids were recently approved for sale in the United States. Research has shown that consumers prefer hearing devices that match their skin color because these devices are less noticeable. Colorism is discrimination against individuals with relatively darker skin that manifests in “skin-color” product offerings as products being offered primarily in relatively lighter colors. Methods: This study compared images of U.S. Food and Drug Administration (FDA)-registered over-the-counter hearing aids to a range of human skin colors. Results: Most over-the-counter hearing aids are only offered in relatively lighter beige colors. Few over-the-counter hearing aids are available in darker skin colors. Conclusions: These findings may represent structural bias, preventing equitable access to darker skin-color OTC hearing aids for individuals with darker skin. Full article
(This article belongs to the Special Issue Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment)
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13 pages, 7876 KiB  
Article
Renewed Concept of Mastoid Cavity Obliteration with the Use of Temporoparietal Fascial Flap Injected by Injectable Platelet-Rich Fibrin after Subtotal Petrosectomy for Cochlear Implant Patients
by Aleksander Zwierz, Krystyna Masna, Paweł Burduk, Stephan Hackenberg and Matthias Scheich
Audiol. Res. 2024, 14(2), 280-292; https://doi.org/10.3390/audiolres14020025 - 1 Mar 2024
Viewed by 1380
Abstract
Background: The subtotal petrosectomy procedure may be useful for cochlear implantation in selected patient groups. Although it is highly effective, complications can arise, which may have economic implications for the patient due to the high cost of the device. Therefore, several authors have [...] Read more.
Background: The subtotal petrosectomy procedure may be useful for cochlear implantation in selected patient groups. Although it is highly effective, complications can arise, which may have economic implications for the patient due to the high cost of the device. Therefore, several authors have attempted to identify the most effective concept for obliteration. Methods: We present a pilot descriptive study of application techniques for obliterating cavities after subtotal petrosectomy using a temporoparietal fascial flap (TPFF) modified with injectable platelet-rich fibrin (IPRF+) for three cochlear implant (CI) patients. Results: Our concept preserves important anatomical structures, such as the temporalis muscle, which covers the CI receiver–stimulator. Injection of IPRF+ also increases the available tissue volume for obliteration and enhances its anti-inflammatory and regenerative potential. Conclusions: To the best of our knowledge, the use of TPFF for filling the cavity has not been adopted for CI with SP and for blind sac closure. Our literature review and our experience with this small group of patients suggest that this procedure, when combined with IPRF+ injections, may reduce the risk of potential infection in the obliterated cavity, particularly when used with CI. This technique is applicable only in cases when the surgeons are convinced that the middle ear cavity is purged of cholesteatoma. Full article
(This article belongs to the Special Issue Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment)
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Review

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11 pages, 728 KiB  
Review
Congenital Cytomegalovirus-Related Hearing Loss
by Nicoleta Gana, Iulia Huluță, Mihai-Ștefan Cătănescu, Livia-Mihaela Apostol, Florina Mihaela Nedelea, Romina-Marina Sima, Radu Botezatu, Anca Maria Panaitescu and Nicolae Gică
Audiol. Res. 2024, 14(3), 507-517; https://doi.org/10.3390/audiolres14030043 - 16 Jun 2024
Cited by 1 | Viewed by 1239
Abstract
Congenital hearing loss is a significant global health concern that affects millions of newborns and infants worldwide, posing substantial challenges for affected individuals, their families, and healthcare systems. This condition, present at birth, can stem from genetic factors, in utero exposures, infections, or [...] Read more.
Congenital hearing loss is a significant global health concern that affects millions of newborns and infants worldwide, posing substantial challenges for affected individuals, their families, and healthcare systems. This condition, present at birth, can stem from genetic factors, in utero exposures, infections, or complications during pregnancy or childbirth. The spectrum of congenital hearing loss ranges from mild to profound, impacting the development of speech, language, and cognitive skills, thereby influencing educational achievements, social integration, and future employment opportunities. Early detection and intervention strategies, such as newborn hearing screenings, genetic counseling, and the use of hearing aids or cochlear implants, are crucial for mitigating these impacts. This review article aims to explore the diagnostic approaches and management strategies for congenital cytomegalovirus-related hearing loss, emphasizing the importance of interdisciplinary care and the potential for technological advances to improve outcomes for affected individuals. Full article
(This article belongs to the Special Issue Hearing Loss: Causes, Symptoms, Diagnosis, and Treatment)
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