Diagnosis and Psychological Intervention for Bipolar Disorder: From Childhood to Adulthood

A special issue of Behavioral Sciences (ISSN 2076-328X). This special issue belongs to the section "Health Psychology".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 1748

Special Issue Editors


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Guest Editor
1. Mental Health Department, ASL Roma 5 Hospital, 00184 Rome, Italy
2. Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy
Interests: psychological mechanisms of emotion regulation in bipolar disorder; psychiatric rehabilitation for severe mental illness; social cognition in psychosis; cognitive assessment and cognitive remediation for psychosis and major depression; CBT- oriented treatment for severe mental illness

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Guest Editor
Mental Health Department, ASL Roma 5 Hospital, 00184 Rome, Italy
Interests: psychiatric community treatment; case management; psychopharmacology; severe mental illness; early psychosis; schizophrenia

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Guest Editor
Mental Health Department, ASL Roma 5 Hospital, 00184 Rome, Italy
Interests: clinical psychology; neuropsychology; cognitive neuroscience; cognitive neuropsychology; mood disorders; psychotic disorders; anxiety disorders; trauma and stressors related disorders; cognitive behavioral therapy

Special Issue Information

Dear Colleagues,

Bipolar disorder (BD) is a chronic and disabling disease that affects about 2–6% of the world’s population, with lifetime incidence at 2%. The onset of BD generally occurs in late adolescence, however, in recent years, cases involving children have increased. In these latter circumstances it becomes very important to make a proper diagnosis, especially for overlaps with other psychiatric conditions, such as ADHD symptoms, or psychopathological dimensions, such as emotional dysregulation.

Little is known about the causes of BD, but the most relevant theories support the hypothesis of an early development of the disorder, in which oxidative stress and traumatic events play a fundamental role.

Pharmacological treatment is essential to stabilize the mood and to allow young people with BD to participate in psychoeducational treatments and in psychological interventions. BD can lead to impairments in personal and social functioning and can cause cognitive disorders that make recovery even more difficult.

Therefore, it is essential to treat BD in an integrated way with the goal of reducing relapses and obtaining personal recovery.

In light of these premises, this Special Issue aims to advance the literature on BD from interdisciplinary perspectives. We therefore welcome theoretical and/or empirical contributions that broaden knowledge on all factors and mechanisms leading to the development of BD from childhood, involving diagnosis, pathophysiologic models, as well as pharmacological and psychological interventions of this chronic and severe mental illness.

Dr. Laura Bernabei
Dr. Enrico Pompili
Dr. Valentina Piserchia
Guest Editors

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Keywords

  • bipolar disorder
  • child and adolescent psychiatry
  • psychological interventions
  • social rhythm regulation
  • substance abuse
  • cognitive behavioral therapy
  • emotion dysregulation
  • mood disorders
  • pathophysiologic models

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Published Papers (1 paper)

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Review

29 pages, 662 KiB  
Review
Neuromodulation Strategies in Lifelong Bipolar Disorder: A Narrative Review
by Laura Bernabei, Beniamino Leone, Daniele Hirsch, Valentina Mentuccia, Alessia Panzera, Francesco Riggio, Loredana Sangiovanni, Valentina Piserchia, Giuseppe Nicolò and Enrico Pompili
Behav. Sci. 2024, 14(12), 1176; https://doi.org/10.3390/bs14121176 - 8 Dec 2024
Viewed by 1050
Abstract
Bipolar disorder is a debilitating psychiatric condition characterized by recurrent episodes of mania and depression, affecting millions worldwide. While pharmacotherapy remains the cornerstone of treatment, a significant proportion of patients exhibit inadequate response or intolerable side effects to conventional medications. In recent years, [...] Read more.
Bipolar disorder is a debilitating psychiatric condition characterized by recurrent episodes of mania and depression, affecting millions worldwide. While pharmacotherapy remains the cornerstone of treatment, a significant proportion of patients exhibit inadequate response or intolerable side effects to conventional medications. In recent years, neuromodulation techniques have emerged as promising adjunctive or alternative treatments for bipolar disorder. We performed a narrative review, according to the Scale for the Assessment of Narrative Review Articles (SANRA) guidelines, to provide a comprehensive overview of the current literature on neuromodulation interventions in bipolar disorder across the course of lifespan. Specifically, it examines the efficacy, safety, and mechanisms of action of various neuromodulation strategies, including, among others, transcranial magnetic stimulation (TMS), electroconvulsive therapy (ECT), vagus nerve stimulation (VNS), deep brain stimulation (DBS), and it describes the therapeutic experiences across the different ages of illness. Additionally, this review discusses the clinical implications, challenges, and future directions of the integration, in clinical practice, of neuromodulation into the management of bipolar disorder. By synthesizing evidence from different studies, this review aims to inform clinicians, researchers, and stakeholders about the evolving landscape of neuromodulation treatments and their potential role in improving outcomes for individuals with bipolar disorder. Full article
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