Recent Progress in Craniofacial Regeneration

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".

Deadline for manuscript submissions: 1 March 2025 | Viewed by 889

Special Issue Editors


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Guest Editor
Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China
Interests: dental stem cell
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China
Interests: craniofacial development; neural crest development; craniofacial birth defects

Special Issue Information

Dear Colleagues,

Traditional approaches for the restoration of defective craniofacial tissues mainly involve the use of prostheses and tissue grafts; however, these approaches either fail to fully restore the functions or cause damage to otherwise healthy tissues. Therefore, there is a drive to develop new treatment strategies to restore craniofacial defects caused by hereditary defects, diseases, and trauma, with craniofacial regeneration at the center of these efforts. Craniofacial regeneration can be achieved by activating the hidden regenerative potential of damaged tissues or by introducing stem cells to the site of the defect and guiding them to carry out tissue regeneration. The realization of craniofacial regeneration requires cross-disciplinary efforts from both biological sciences and biomaterial and tissue engineering.

In this Special Issue, we aim to showcase the latest advancements in craniofacial stem cell development, bone biology, organoid, biomaterials, tissue engineering, and other research fields that can potentially transform the future of craniofacial regeneration. Reviews and clinical studies on craniofacial regeneration are also welcome.

Prof. Dr. Chengfei Zhang
Dr. Zhaoming Wu
Guest Editors

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Keywords

  • craniofacial regeneration
  • regenerative medicine
  • tissue engineering
  • craniofacial stem cells
  • organoid
  • biomaterials

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Published Papers (1 paper)

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Review

19 pages, 648 KiB  
Review
Optimization and Implication of Adipose-Derived Stem Cells in Craniofacial Bone Regeneration and Repair
by Cong Gu, Qinghuang Tang, Liwen Li and YiPing Chen
Bioengineering 2024, 11(11), 1100; https://doi.org/10.3390/bioengineering11111100 - 31 Oct 2024
Viewed by 559
Abstract
Adipose-derived stem cells (ADSCs) have emerged as a promising resource for craniofacial bone regeneration due to their high abundance and easy accessibility, significant osteogenic potential, versatile applications, and potential for personalized medicine, which underscore their importance in this field. This article reviews the [...] Read more.
Adipose-derived stem cells (ADSCs) have emerged as a promising resource for craniofacial bone regeneration due to their high abundance and easy accessibility, significant osteogenic potential, versatile applications, and potential for personalized medicine, which underscore their importance in this field. This article reviews the current progress of preclinical studies that describe the careful selection of specific ADSC subpopulations, key signaling pathways involved, and usage of various strategies to enhance the osteogenic potential of ADSCs. Additionally, clinical case reports regarding the application of ADSCs in the repair of calvarial defects, cranio-maxillofacial defects, and alveolar bone defects are also discussed. Full article
(This article belongs to the Special Issue Recent Progress in Craniofacial Regeneration)
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