Devices for Vascular Intervention

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: closed (31 January 2025) | Viewed by 2765

Special Issue Editors


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Guest Editor
Global Institute of Future Technology, Shanghai Jiao Tong University, Shanghai 200240, China
Interests: biomedical manufacturing; interventional medical devices; brain-computer interface

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Guest Editor
Worcester Polytechnic Institute, Worcester, MA, USA
Interests: medical devices

Special Issue Information

Dear Colleagues,

Vascular interventions have revolutionized the field of medicine, enabling minimally invasive procedures for the treatment of various cardiovascular conditions. The development of advanced devices plays a pivotal role in improving patient outcomes, enhancing precision, and minimizing procedure-related risks. This Special Issue aims to shed light on the cutting-edge research and technological advances in the design, development, and application of devices for vascular intervention. The scope of this Special Issue encompasses a wide range of topics, including but not limited to novel device designs and engineering concepts, catheter-based intervention technologies, guidewires and microcatheters, balloon angioplasty and stent deployment systems, vascular closure devices, embolic protection devices, intravascular imaging and diagnostic tools, robotics and remote navigation systems, biomaterials, and biocompatible coatings, as well as emerging technologies for minimally invasive procedures.

Dr. Yang Liu
Dr. Yihao Zheng
Guest Editors

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Keywords

  • device technologies
  • minimally invasive procedures
  • catheter-based interventions
  • guidewires
  • stent
  • thrombosis
  • atherosclerosis
  • stroke

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Published Papers (2 papers)

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Research

16 pages, 4411 KiB  
Article
Evaluation of a Semi-Automated Ultrasound Guidance System for Central Vascular Access
by Sofia I. Hernandez Torres, Nicole W. Caldwell and Eric J. Snider
Bioengineering 2024, 11(12), 1271; https://doi.org/10.3390/bioengineering11121271 - 15 Dec 2024
Viewed by 681
Abstract
Hemorrhage remains a leading cause of death in both military and civilian trauma settings. Oftentimes, the control and treatment of hemorrhage requires central vascular access and well-trained medical personnel. Automated technology is being developed that can lower the skill threshold for life-saving interventions. [...] Read more.
Hemorrhage remains a leading cause of death in both military and civilian trauma settings. Oftentimes, the control and treatment of hemorrhage requires central vascular access and well-trained medical personnel. Automated technology is being developed that can lower the skill threshold for life-saving interventions. Here, we conduct independent evaluation testing of one such device, the Vu-Path™ Ultrasound Guidance system, or Vu-Path™. The device was designed to simplify needle insertion using a needle holder that ensures the needle is within the ultrasound field of view during its insertion into tissue, along with guidance lines shown on the user interface. We evaluated the performance of this device in a range of laboratory, animal, and human testing platforms. Overall, the device had a high success rate, achieving an 83% insertion accuracy in live animal testing across both normal and hypotensive blood pressures. Vu-Path™ was faster than manual, ultrasound-guided needle insertion and was nearly 1.5 times quicker for arterial and 2.3 times quicker for venous access. Human usability feedback highlighted that 80% of the participants would use this device for central line placement. Study users noted that the guidance lines and small form factor were useful design features. However, issues were raised regarding the needle insertion angle being too steep, with potential positioning challenges as the needle remains fixed to the ultrasound probe. Regardless, 75% of the participants believed that personnel with any level of clinical background could use the device for central vascular access. Overall, Vu-Path™ performed well across a range of testing situations, and potential design improvements were noted. With adjustments to the device, central vascular access can be made more accessible on battlefields in the future. Full article
(This article belongs to the Special Issue Devices for Vascular Intervention)
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15 pages, 7665 KiB  
Communication
Simplified Models to Assess the Mechanical Performance Parameters of Stents
by Juan P. Toledo, Jaime Martínez-Castillo, Diego Cardenas, Enrique Delgado-Alvarado, Marco Osvaldo Vigueras-Zuñiga and Agustín L. Herrera-May
Bioengineering 2024, 11(6), 583; https://doi.org/10.3390/bioengineering11060583 - 7 Jun 2024
Cited by 1 | Viewed by 1628
Abstract
Ischemic heart disease remains a leading cause of mortality worldwide, which has promoted extensive therapeutic efforts. Stenting has emerged as the primary intervention, particularly among individuals aged 70 years and older. The geometric specifications of stents must align with various mechanical performance criteria [...] Read more.
Ischemic heart disease remains a leading cause of mortality worldwide, which has promoted extensive therapeutic efforts. Stenting has emerged as the primary intervention, particularly among individuals aged 70 years and older. The geometric specifications of stents must align with various mechanical performance criteria outlined by regulatory agencies such as the Food and Drug Administration (FDA). Finite element method (FEM) analysis and computational fluid dynamics (CFD) serve as essential tools to assess the mechanical performance parameters of stents. However, the growing complexity of the numerical models presents significant challenges. Herein, we propose a method to determine the mechanical performance parameters of stents using a simplified FEM model comprising solid and shell elements. In addition, a baseline model of a stent is developed and validated with experimental data, considering parameters such as foreshortening, radial recoil, radial recoil index, and radial stiffness of stents. The results of the simplified FEM model agree well with the baseline model, decreasing up to 80% in computational time. This method can be employed to design stents with specific mechanical performance parameters that satisfy the requirements of each patient. Full article
(This article belongs to the Special Issue Devices for Vascular Intervention)
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