Metallo-Enzymes as Drug Targets
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".
Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 2590
Special Issue Editors
Interests: structural biology; protein crystallography; drug design; carbonyc anhydrases
Special Issues, Collections and Topics in MDPI journals
Interests: carbonic anhydrase; protein engineering; cancer; molecular biology; protein characterization
Interests: tumor associated proteins; carbonic anhydrase; intrinsically disordered proteins; CAF-1 chemical biology; protein–protein interaction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
A huge amount of studies described the involvement of metalloenzymes in a variety of biological processes, which span from DNA modification to protein degradation, antibiotic resistance and many others. Their overexpression, enhanced activation or misregulation can cause severe diseases. For this reason, metalloenzymes have been deeply investigated as drug targets and even more increasing interest is on the way. Important strategies have been developed to gain novel inhibitors to be used as drugs in pharmaceutical field.
In this issue, we will summarize the most important results obtained in this field and provide future perspectives for the development of novel drug classes. Topics of interest could include, but are not limited to, metalloenzyme as drug targets for the development of novel antibacterial, anti-infective and anticancer agents.
Dr. Giuseppina De Simone
Dr. Martina Buonanno
Dr. Simona Maria Monti
Guest Editors
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Keywords
- metalloenzyme
- drug design
- anticancer drug
- antibacterial drug
- drug target
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