Bio-Inspired Additive Manufacturing Materials and Structures

A special issue of Biomimetics (ISSN 2313-7673). This special issue belongs to the section "Biomimetics of Materials and Structures".

Deadline for manuscript submissions: 30 December 2024 | Viewed by 2034

Special Issue Editor


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Guest Editor
William States Lee College of Engineering, Charlotte, NC 28223, USA
Interests: advanced manufacturing; bio-inspired design; soft robotics; data driven additive manufacturing; multi-material multi-scale hierarchical surfaces

Special Issue Information

Dear Colleagues,

This special issue explores the forefront of bio-inspired additive manufacturing (AM), where the intricacies of nature are harnessed to revolutionize material and structural design. By integrating biological principles of design and functionality with advanced AM techniques, researchers can create innovative and sustainable solutions. We invite contributions that investigate the use of bio-inspired designs and processes in the additive manufacturing of polymers, polymer composites, and ceramics, pushing the boundaries of what's possible in these materials. Additionally, we are keen on papers that explore the application of bio-inspired AM in the burgeoning field of soft robotics, where flexible and adaptive structures can benefit immensely from nature-inspired solutions. Topics of interest include biomimetic design, material synthesis, hierarchical and multifunctional structures, and applications across sectors such as healthcare, aerospace, and environmental engineering.This issue aims to highlight the transformative potential of integrating biological inspiration with additive manufacturing, fostering innovations that can meet the challenges of modern engineering and materials science.

Dr. Erina Baynojir Joyee
Guest Editor

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Keywords

  • biomimetic design
  • additive manufacturing
  • 3D printing
  • polymer AM
  • ceramic AM
  • bio-inspired materials
  • soft robotics
  • hierarchical structures
  • sustainable fabrication
  • multifunctional materials

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Published Papers (2 papers)

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Research

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12 pages, 1792 KiB  
Article
3D Printing Materials Mimicking Human Tissues after Uptake of Iodinated Contrast Agents for Anthropomorphic Radiology Phantoms
by Peter Homolka, Lara Breyer and Friedrich Semturs
Biomimetics 2024, 9(10), 606; https://doi.org/10.3390/biomimetics9100606 - 8 Oct 2024
Viewed by 1121
Abstract
(1) Background: 3D printable materials with accurately defined iodine content enable the development and production of radiological phantoms that simulate human tissues, including lesions after contrast administration in medical imaging with X-rays. These phantoms provide accurate, stable and reproducible models with defined iodine [...] Read more.
(1) Background: 3D printable materials with accurately defined iodine content enable the development and production of radiological phantoms that simulate human tissues, including lesions after contrast administration in medical imaging with X-rays. These phantoms provide accurate, stable and reproducible models with defined iodine concentrations, and 3D printing allows maximum flexibility and minimal development and production time, allowing the simulation of anatomically correct anthropomorphic replication of lesions and the production of calibration and QA standards in a typical medical research facility. (2) Methods: Standard printing resins were doped with an iodine contrast agent and printed using a consumer 3D printer, both (resins and printer) available from major online marketplaces, to produce printed specimens with iodine contents ranging from 0 to 3.0% by weight, equivalent to 0 to 3.85% elemental iodine per volume, covering the typical levels found in patients. The printed samples were scanned in a micro-CT scanner to measure the properties of the materials in the range of the iodine concentrations used. (3) Results: Both mass density and attenuation show a linear dependence on iodine concentration (R2 = 1.00), allowing highly accurate, stable, and predictable results. (4) Conclusions: Standard 3D printing resins can be doped with liquids, avoiding the problem of sedimentation, resulting in perfectly homogeneous prints with accurate dopant content. Iodine contrast agents are perfectly suited to dope resins with appropriate iodine concentrations to radiologically mimic tissues after iodine uptake. In combination with computer-aided design, this can be used to produce printed objects with precisely defined iodine concentrations in the range of up to a few percent of elemental iodine, with high precision and anthropomorphic shapes. Applications include radiographic phantoms for detectability studies and calibration standards in projective X-ray imaging modalities, such as contrast-enhanced dual energy mammography (abbreviated CEDEM, CEDM, TICEM, or CESM depending on the equipment manufacturer), and 3-dimensional modalities like CT, including spectral and dual energy CT (DECT), and breast tomosynthesis. Full article
(This article belongs to the Special Issue Bio-Inspired Additive Manufacturing Materials and Structures)
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Review

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14 pages, 510 KiB  
Review
Surface Functionalization of 3D-Printed Bio-Inspired Scaffolds for Biomedical Applications: A Review
by Yeon Soo Kim and Yoo Seob Shin
Biomimetics 2024, 9(11), 703; https://doi.org/10.3390/biomimetics9110703 - 16 Nov 2024
Viewed by 525
Abstract
Three-dimensional (3D) printing is a highly effective scaffold manufacturing technique that may revolutionize tissue engineering and regenerative medicine. The use of scaffolds, along with growth factors and cells, remains among the most promising approaches to organ regeneration. However, the applications of hard 3D-printed [...] Read more.
Three-dimensional (3D) printing is a highly effective scaffold manufacturing technique that may revolutionize tissue engineering and regenerative medicine. The use of scaffolds, along with growth factors and cells, remains among the most promising approaches to organ regeneration. However, the applications of hard 3D-printed scaffolds may be limited by their poor surface properties, which play a crucial role in cell recruitment and infiltration, tissue–scaffold integration, and anti-inflammatory properties. However, various prerequisites must be met before 3D-printed scaffolds can be applied clinically to the human body. Consequently, various attempts have been made to modify the surfaces, porosities, and mechanical properties of these scaffolds. Techniques that involve the chemical and material modification of surfaces can also be applied to enhance scaffold efficacy. This review summarizes the characteristics and discusses the developmental directions of the latest 3D-printing technologies according to its intended application in unmet clinical needs. Full article
(This article belongs to the Special Issue Bio-Inspired Additive Manufacturing Materials and Structures)
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