The Physiological and Pathological New Function of Mitochondrial ROS and Intraorganellar Cross-Talks
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: closed (3 April 2023) | Viewed by 4675
Special Issue Editors
Interests: mitochondria; oxidative stress; cell signaling; mitochondrial DNA; mitochondrial RNA; lipid peroxidation; hair; neuron; aging
Special Issues, Collections and Topics in MDPI journals
Interests: Nrf2; ATF4; mito-nuclear communication; mitochondrial antioxidant; Keap1; anti-aging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Thijsj G. Rttema described “Mitochondria in the second act”, citing Pittis and Gabaldón (page 101), who provide evidence that the host cell from which eukaryotes evolved was already genetically chimaeric before the mitochondrial symbiosis, suggesting that mitochondria evolved later in eukaryotic evolution than was previously presumed (https://www.nature.com/articles/nature16876; Nature volume 531, pages 39–40 (03 March 2016)). This means that when mitochondria are established, it is possible to commence cross-talk between mitochondria and other organelles. This is one of the newest topics to reconsider intracellular organelle cross-talk. Majima et al. were the first to report that reactive oxygen species (ROS) generated from mitochondria promote apoptosis (Majima et al., J Biol. Chem. 1998), while Itoh et al. described the function of the Nrf2-Keap1 intercellular signal for the first time (Itoh et al., Biochem. Biophys. Res. Commun. 1997, Itoh et al., Genes Dev. 1999). A recent study has described that ROS generated from mitochondria initiate cellular transduction in cytosol (Indo et al. Handb Exp Pharmacol. 2017). In this Special Issue, the further roles of mitochondria-generated ROS and the subsequent intraorganellar cross-talks, signal exchange, and protein import will be important to retain cellular networks and homeostasis. We aim to establish a new world of cellular functions.
Prof. Dr. Hideyuki J. Majima
Prof. Dr. Ken Itoh
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- mitochondrial ROS
- cellular signaling
- intraorganellar cross-talks
- mito-nuclear communication
- mitochondrial antioxidant
- aging
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
