PARPs in Cell Death and PARP Inhibitors in Cancers: 2nd Edition
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 10 July 2025 | Viewed by 678
Special Issue Editors
Interests: cancer; SWI/SNF complex; PARP
Special Issues, Collections and Topics in MDPI journals
Interests: cancer; cancer-stem-like cells; oxidative stress; circadian clock
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Following a very successful first edition, we are pleased to announce the launch of a second edition of this Special Issue, entitled “PARPs in Cell Death and PARP Inhibitors in Cancers”.
Poly (ADP-ribose) polymerases (PARPs) are a family of related enzymes that participate in many cellular processes such as DNA repair, genomic stability, transcription, replication, mitosis, cell growth, and programmed cell death. Combined with the concept of synthetic lethality, PARP inhibitors have been developed to inhibit the growth of cancer cells and kill them. At present, four PARP inhibitors have been approved by the United States Food and Drug Administration for the treatment of ovarian cancer, breast cancer, pancreatic cancer, and other cancers.
Nevertheless, the process via which PARP participates in cells still needs to be explored in order to enhance the applicative value of PARP and PARP inhibitors.
This Special Issue welcomes the submission of original research or review articles that address the role of PARPs in cell death and the application of PARP inhibitors in cancers. We look forward to receiving your contributions.
Dr. María Isabel Rodríguez
Dr. Josefa León
Guest Editors
Manuscript Submission Information
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Keywords
- PARPs
- PARP inhibitors
- cancers
- cell death
- DNA repair
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Related Special Issue
- PARPs in Cell Death and PARP Inhibitors in Cancers in Biomolecules (4 articles)
