The Role of Astrocytes in Neurodegenerative Diseases
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 879
Special Issue Editor
Interests: neurodegeneration; neuroinflammation; neuropharmacology; neuropsychology; neural stem cells
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Astrocytes, a prominent subtype of glial cells in the central nervous system, play crucial roles in metabolic support, structural integrity, and neuroprotection. They contribute significantly to maintaining homeostasis, clearing neurotransmitters, regulating the blood–brain barrier, and facilitating synaptic function. Dysfunctions in astrocytes and their transformation into reactive states due to pathological stimuli have been linked to the pathogenesis of various neurodegenerative disorders.
This Special Issue aims to highlight cutting-edge research on the involvement of astrocytes in the pathophysiology of neurodegenerative diseases. We invite submissions of original research articles, reviews, and communications that explore any aspect of astrocytic functions and dysfunctions in neurodegeneration.
Topics of interest include, but are not limited to, the following:
- Molecular mechanisms underlying astrocyte–neuron interactions in neurodegenerative diseases;
- The role of astrocytes in the clearance of misfolded proteins and neurotoxic molecules;
- Astrocytic contributions to inflammation and neuroinflammatory responses;
- Implications of astrocytic dysfunction in synaptic dysfunction and neuronal death;
- Therapeutic strategies targeting astrocytes for neuroprotection and neuroregeneration.
Dr. Nima Sanadgol
Guest Editor
Manuscript Submission Information
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Keywords
- astrocytes
- neurodegeneration
- neuroinflammation
- neuroprotection
- neuroregeneration
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