The Role of Biomolecules in Tumor Microenvironment
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (15 December 2022) | Viewed by 5236
Special Issue Editors
Interests: gene therapy; cell and tissue engineering; vaccine development; biomaterials; synthetic biology; metabolic engineering and biorefinery
Special Issue Information
Dear Colleagues,
The tumor microenvironment (TME) is a complex environment that comprises cancer cells, stromal cells, extracellular matrix, lymphatic cells, vasculature, and signaling molecules. The biomolecules generated in such a suppressive milieu (e.g., metabolites, exosomes) can be viewed as diagnostic and prognostic biomarkers to characterize the current stage and behavior of the tumor and even understand the development of the tumor. By contrast, the biomolecules that directly or indirectly alter the tumor microenvironment (e.g., proteinases) can potentially become therapeutic agents to block or reduce the development progress of tumors for cancer treatment. Understanding this dynamic and intricate interaction between biomolecules and the tumor microenvironment could help to translate fundamental research toward clinical applications.
Prof. Dr. Yu-Chen Hu
Dr. Jen-Huang Huang
Guest Editors
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Keywords
- tumour microenvironment
- diagnosis
- treatment
- metobolites
- ECM remodeling
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