Molecular Pathology, Diagnostics, Treatments and Holistic Care of Multiple Sclerosis
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 6572
Special Issue Editor
Special Issue Information
Dear Colleagues,
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the CNS, presents with progressive muscle destruction. Genetic and environmental factors determine its pathogenesis. Multitude of symptoms affecting physical and cognitive function as well as mood that generally results in a gradual accumulation of permanent disability in these patients, affecting every aspect of their lives.
In recent years, methods of diagnosis and differentiation of MS have developed at the clinical and molecular level. However, due to the great heterogeneity of the pathophysiological processes that occur in the onset and development of the disease, it is necessary to continue studying clinical and molecular tools that improve early diagnosis and help the management of the disease in clinical practice, as biomarkers, to improve prognosis and monitor response to treatment. Among these, molecules that have been increased in MS patients related to inflammatory processes, or molecules of an inflammatory nature whose levels are shown to decrease after some type of therapeutic intervention. may be of interest.
Regarding therapeutic advances, both pharmacological and physiotherapeutic therapies have been developed in recent years. The improvements obtained with certain nutritional interventions, and those obtained with the administration of antioxidants that improve the level of inflammation and oxidation, are especially interesting. Both strategies are aimed at improving energetic alterations at the mitochondrial level, acting as effective neuroprotectors for these patients.
The upcoming Special Issue will cover molecular mechanism of pathogenesis, diagnostics aspects, and interventions or tools to do possible the holistic care of patients with MS. So that, we invite researchers to submit original articles or state-of-the art reviews on these fields. All contributions will undergo a rapid, fair, and concise review process to minimize publication times.
Prof. Dr. María M. López-Rodríguez
Guest Editor
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Keywords
- multiple sclerosis
- biomarkers
- diet
- inflammation
- quality of life
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