Materials and Techniques for Bioanalysis and Biosensing (Volume II)

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 1655

Special Issue Editor


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Guest Editor
State Key Laboratory of Digital Biomedical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China
Interests: nanotechnology; biosensors; biomaterials; controlled drug delivery; biochips; microarrays; biomedical devices
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Special Issue Information

Dear Colleagues,

Bioanalysis and biosensors are ever-evolving subjects, striving for rapid improvement in terms of performance and expanding the target range to meet the enormous societal and market demands. The key performance factors for a biosensor that drive the research are sensitivity, selectivity, accuracy, reproducibility, and response time, with additional requirements of its portability and inexpensive nature. These performance factors are largely governed by the materials and techniques being used in these bioanalytical platforms. The selection of materials to meet these requirements is critical, as their interaction or involvement with the biological recognition elements should initiate or improve these performance factors. The technique discussed primarily applies to transducers involved in converting a biochemical signal to optical or electrical signals. In recent years, the emergence of novel materials and techniques has drastically improved the performance of these bioanalytical systems, enabling them to expand their analytical horizons. These advanced materials and techniques are central to modern bioanalytical and biosensor research. This Special Issue offers new perspectives on the recent advance in materials and techniques for bioanalysis and biosensing.

This Research Topic will accept submissions that cover areas including, but not limited to:

  • Biosensing principles and strategies for various targets;
  • Smart materials for biosensors and other rapid, portable detection devices;
  • Nanozymes as potential catalysts for sensing applications;
  • Electrochemical, electrochemiluminescence and photoelectrochemical-based biosensors;
  • Colorimetric, fluorescence, luminescence, and SPR biosensors;
  • Biological recognition and affinity-based biosensors;
  • Paper electronics and paper-based biosensors;
  • FET-based biosensors, including ISFET and BioFET;
  • Emerging materials for bioanalysis and biosensing;
  • New technologies for signal transducers.

Prof. Dr. Nongyue He
Guest Editor

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Keywords

  • nanomaterials
  • transducers
  • biosensing
  • enzyme sensors
  • immune sensors
  • DNA/RNA sensors
  • aptamer biosensors
  • optical sensors
  • electrochemical biosensors
  • photoelectrochemical biosensors
  • ECL biosensors
  • paper-based biosensors
  • wearable biosensors
  • FET biosensors

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Published Papers (1 paper)

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Research

16 pages, 3408 KiB  
Article
CoMnOx Nanoflower-Based Smartphone Sensing Platform and Virtual Reality Display for Colorimetric Detection of Ziram and Cu2+
by Chang Song, Fangfang Wang, Xin Zhang, Yuanxia Ma, Yangyu Wu, Mingxia He, Xiangheng Niu and Mengmeng Sun
Biosensors 2024, 14(4), 178; https://doi.org/10.3390/bios14040178 - 6 Apr 2024
Viewed by 1400
Abstract
Transition metal doping is an ideal strategy to construct multifunctional and efficient nanozymes for biosensing. In this work, a metal-doped CoMnOx nanozyme was designed and synthesized by hydrothermal reaction and high-temperature calcination. Based on its oxidase activity, an “on-off-on” smartphone sensing platform [...] Read more.
Transition metal doping is an ideal strategy to construct multifunctional and efficient nanozymes for biosensing. In this work, a metal-doped CoMnOx nanozyme was designed and synthesized by hydrothermal reaction and high-temperature calcination. Based on its oxidase activity, an “on-off-on” smartphone sensing platform was established to detect ziram and Cu2+. The obtained flower-shaped CoMnOx could exhibit oxidase-, catalase-, and laccase-like activities. The oxidase activity mechanism of CoMnOx was deeply explored. O2 molecules adsorbed on the surface of CoMnOx were activated to produce a large amount of O2·-, and then, O2·- could extract acidic hydrogen from TMB to produce blue oxTMB. Meanwhile, TMB was oxidized directly to the blue product oxTMB via the high redox ability of Co species. According to the excellent oxidase-like activity of CoMnOx, a versatile colorimetric detection platform for ziram and Cu2+ was successfully constructed. The linear detection ranges for ziram and Cu2+ were 5~280 μM and 80~360 μM, and the detection limits were 1.475 μM and 3.906 μM, respectively. In addition, a portable smartphone platform for ziram and Cu2+ sensing was established for instant analysis, showing great application promise in the detection of real samples including environmental soil and water. Full article
(This article belongs to the Special Issue Materials and Techniques for Bioanalysis and Biosensing (Volume II))
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