Functional Nanomaterials for Biosensing—2nd Edition

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".

Deadline for manuscript submissions: 20 March 2025 | Viewed by 1400

Special Issue Editor

State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing 210023, China
Interests: biosensors; nanomaterials; electrochemical; nucleic acids; proteins
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Special Issue Information

Dear Colleagues,

Biosensors are valuable tools for chemical and biological molecule detection, extensively used in environmental monitoring, food safety, biochemical analysis, disease diagnosis and public safety. In recent decades, the introduction of nanomaterials with outstanding physical and chemical properties has promoted the rapid development of biosensors such as carbon nanotubes, noble metallic nanoparticles, metal oxides, graphene, and two-dimensional transition metal chalcogenides. A popular method of further improving the analytical performance of biosensors is the formation of nanocomposites via hybridizing functional groups with nanomaterials. Functional nanomaterials coupled with electrochemistry, fluorescence, surface-enhanced Raman scattering, field effect transistors, and colorimetry methods have been proven to be a promising sensing platform for nucleic acids, proteins, cancerous cells, and small biological molecule detection in vitro and in vivo. This Special Issue welcomes original research works and high-quality reviews focusing on the following topics related to nanomaterials-based biosensors coupled with different detection techniques for biochemical analysis and disease diagnosis:

  • Novel nanomaterials developed to construct high-performance biosensors;
  • The performance of biosensors improved by new strategies and new analytical methods;
  • Detection of environmental pollutions;
  • Detection of biomarkers, including small biomolecules, nucleic acids, proteins, cells;
  • Detection of bacterial, viruses;
  • Detection of antibiotic, drug residue;
  • Detection of other biomolecules;
  • Development of devices for biosensing.

Dr. Shao Su
Guest Editor

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Keywords

  • nanomaterials
  • biosensors
  • environmental monitoring
  • food safety
  • biochemical analysis
  • disease diagnosis
  • DNA
  • RNA
  • proteins
  • cells
  • virus
  • bacteria

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Published Papers (1 paper)

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Review

14 pages, 7836 KiB  
Review
Recent Progress in the Synthesis of 3D Complex Plasmonic Intragap Nanostructures and Their Applications in Surface-Enhanced Raman Scattering
by Li Ma, Keyi Zhou, Xinyue Wang, Jiayue Wang, Ruyu Zhao, Yifei Zhang and Fang Cheng
Biosensors 2024, 14(9), 433; https://doi.org/10.3390/bios14090433 - 6 Sep 2024
Viewed by 1026
Abstract
Plasmonic intragap nanostructures (PINs) have garnered intensive attention in Raman-related analysis due to their exceptional ability to enhance light–matter interactions. Although diverse synthetic strategies have been employed to create these nanostructures, the emphasis has largely been on PINs with simple configurations, which often [...] Read more.
Plasmonic intragap nanostructures (PINs) have garnered intensive attention in Raman-related analysis due to their exceptional ability to enhance light–matter interactions. Although diverse synthetic strategies have been employed to create these nanostructures, the emphasis has largely been on PINs with simple configurations, which often fall short in achieving effective near-field focusing. Three-dimensional (3D) complex PINs, distinguished by their intricate networks of internal gaps and voids, are emerging as superior structures for effective light trapping. These structures facilitate the generation of hot spots and hot zones that are essential for enhanced near-field focusing. Nevertheless, the synthesis techniques for these complex structures and their specific impacts on near-field focusing are not well-documented. This review discusses the recent advancements in the synthesis of 3D complex PINs and their applications in surface-enhanced Raman scattering (SERS). We begin by describing the foundational methods for fabricating simple PINs, followed by a discussion on the rational design strategies aimed at developing 3D complex PINs with superior near-field focusing capabilities. We also evaluate the SERS performance of various 3D complex PINs, emphasizing their advanced sensing capabilities. Lastly, we explore the future perspective of 3D complex PINs in SERS applications. Full article
(This article belongs to the Special Issue Functional Nanomaterials for Biosensing—2nd Edition)
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