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Biosensors
Special Issues
Metal–Organic Frameworks (MOFs) Coupled with Enzymes as Biosensors
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Metal–Organic Frameworks (MOFs) Coupled with Enzymes as Biosensors

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".

Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 4343

Special Issue Editor

Prof. Dr. José Cleiton Sousa dos Santos

E-Mail Website
Guest Editor
Institute of Engineering and Sustainable Development, University of International Integration of the Afro-Brazilian Lusophony, Redenção 62790-970, Brazil
Interests: enzyme-related processes; biocatalysis; chemistry; biology; materials; energy; environment; food; pharmaceuticals; manufacturing, and related engineering fields
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Metallic–organic structures (MOF) are hybrid inorganic compounds with particular characteristics. MOFs have a well-defined porous structure, huge surface area, and high thermal stability, indicating that they have great potential for enzyme coupling. We can highlight the main characteristics of the biocomposites formed by enzyme–MOF, such as improved catalytic performance, strong interaction between the enzyme and MOF, and the possibility of adding enormous enzyme loads. Different approaches for enzyme immobilization (co-precipitation, biomineralization, encapsulation) in developing enzyme–MOF compounds can be performed. The focus of these preparations includes the design of biocomposites with high enzymatic activity and storage stability as well as improved reaction kinetics, material recycling, and thermal stability. Current strategies can be explored, such as multienzyme systems and the possibility of incorporating magnetic structures. Therefore, this Special Issue, "Metal–Organic Frameworks (MOFs) Coupled with Enzymes as Biosensors", focuses on recent advances in producing new enzyme–MOF biocomposites for use as biosensors. We invite research submissions that help to advance the field of MOF–enzyme technology and its application in high-performance biosensor analysis.

With best regards,

Prof. Dr. José C.S. dos Santos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensor
  • enzyme
  • metal–organic frameworks
  • biocomposites
  • multienzyme
  • immobilization
  • co-precipitation
  • biomineralization
  • encapsulation
  • sensing

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Published Papers (1 paper)

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20 pages, 7388 KiB  
Review
Electrochemical-Based Sensing Platforms for Detection of Glucose and H2O2 by Porous Metal–Organic Frameworks: A Review of Status and Prospects
by Hessamaddin Sohrabi, Fatemeh Maleki, Pegah Khaaki, Mohammed Kadhom, Nurbolat Kudaibergenov and Alireza Khataee
Biosensors 2023, 13(3), 347; https://doi.org/10.3390/bios13030347 - 4 Mar 2023
Cited by 41 | Viewed by 4016
Abstract
Establishing enzyme-free sensing assays with great selectivity and sensitivity for glucose and H2O2 detection has been highly required in biological science. In particular, the exploitation of nanomaterials by using noble metals of high conductivity and surface area has been widely [...] Read more.
Establishing enzyme-free sensing assays with great selectivity and sensitivity for glucose and H2O2 detection has been highly required in biological science. In particular, the exploitation of nanomaterials by using noble metals of high conductivity and surface area has been widely investigated to act as selective catalytic agents for molecular recognition in sensing platforms. Several approaches for a straightforward, speedy, selective, and sensitive recognition of glucose and H2O2 were requested. This paper reviews the current progress in electrochemical detection using metal–organic frameworks (MOFs) for H2O2 and glucose recognition. We have reviewed the latest electrochemical sensing assays for in-place detection with priorities including straightforward procedure and manipulation, high sensitivity, varied linear range, and economic prospects. The mentioned sensing assays apply electrochemical systems through a rapid detection time that enables real-time recognition. In profitable fields, the obstacles that have been associated with sample preparation and tool expense can be solved by applying these sensing means. Some parameters, including the impedance, intensity, and potential difference measurement methods have permitted low limit of detections (LODs) and noticeable durations in agricultural, water, and foodstuff samples with high levels of glucose and H2O2. Full article
(This article belongs to the Special Issue Metal–Organic Frameworks (MOFs) Coupled with Enzymes as Biosensors)
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