Functional Polymers for Biosensing
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".
Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 2072
Special Issue Editor
Interests: assembly of conductive polymer micro/nano structures; preparation of organic-inorganic nanocomposite materials; electrochemical biosensors; supercapacitors
Special Issue Information
Dear Colleagues,
Over the past decade, a great variety of polymer-based biosensors have been reported in the literature, referring to particular polymers such as polyethyleneimine, polyaniline, PEDOT, or polypyrrole, and derivatives obtained either by electropolymerization or by chemical polymerization, combined with nanomaterials such as CNTs, graphene, or gold nanoparticles. Electropolymerization in deep eutectic solvents (DES) is another interesting approach, and the polymers produced through this method exhibit improved features compared with the same polymers obtained in aqueous solutions.
One of the most important aspects in the development of biosensors is the immobilization platform, which needs to ensure a high stability for the molecular biorecognition compound and to maintain its activity for as long as possible. Entrapment in a polymeric matrix or the employment of a particularly functionalized polymeric film (with amino or carboxyl groups, azide groups for click chemistry, biotine, avidine, or cyclodextrine) are some of the most important immobilization methods for the molecular recognition element in biosensor design. The immobilization of natural receptors (enzyme, antibody, DNA, RNA, peptide, etc.) and biomimetic receptors (ligands such as crown ethers, cryptands, cyclodextrins, or calixarenes) with polymers is one of the most challenging topics.
Nanoparticle–polymer composites are advanced functional materials comprising nanoparticles integrated into a polymer matrix. In addition to the characteristics of polymers, nanocomposites may acquire the outstanding electrical, optical, and magnetic properties of their metal components. Optical nonlinearities and/or infra-low/ultra-high refractive indices make nanocomposites suitable for a number of potential applications, such as ultrathin color filters, UV absorbers, optical sensors, waveguides, optical strain detectors, and thermo-chromic materials. Because of the strong Au and Ag localized surface plasmon resonance (LSPR) bands in the visible spectrum, giving rise to characteristic absorption and strong field confinement and enhancement, some gold nanocomposites are particularly appropriate for sensing applications. LSPR has been extensively exploited for sensing and biosensing, with enormous progress in recent years, both in terms of instrumentation and applications.
The Special Issue aims to highlight not only the most recent advances and challenges, but also the future trends and perspectives in the field of polymer-based biosensors. Reviews and original research papers are all welcome.
Prof. Dr. Xiaomiao Feng
Guest Editor
Manuscript Submission Information
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Keywords
- polymer
- nanocomposite
- biosensor
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