Low-Dimensional Materials in Biosensors, Biophotonics, and Bioelectronics

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".

Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 12148

Special Issue Editor


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Guest Editor
Graduate Institute of Optoelectronic Engineering, National Chung Hsing University, Taichung 402, Taiwan
Interests: metal oxide nanostructure; resistive chemical sensors; light-emitting diode; photodetector; quantum dots

Special Issue Information

Dear Colleagues,

Recent developments in low-dimensional structures, such as nanowire, nanodots, and nanofilms in varieties of material systems covering 2D materials, oxides, and metals, have stimulated exciting research possibilities and applications in biosensors, biophotonics, and bioelectronics. For example, nanowire material provides a large surface-to-volume ratio with enough chemical detection reactions at ultra-low concentrations, useful in an electronic biosensor. Low-dimensional metal structures also induce a plasmonic effect for optical detection of biochemical materials. I am pleased to invite you to contribute to this Special Issue focused on recent advances, future perspectives, and challenges in bio-detection enabled by low-dimensional materials.

The present Special Issue covers all aspects of biosensors, biophotonics, and bioelectronics that utilize low-dimensional materials. The contributed articles include but are not limited to detecting volatile organic compounds, chemicals, neurobiological, glucose, sweat, bacteria, and viruses. Fundamental studies of sensing mechanisms, engineering of biochemical sensing systems, and the rational design of material systems for biochemical sensing are also welcome. Studies on the biochemical sensing utilizing materials include 2D materials, such as graphene, MoS2, MoSe2, metal oxides, such as zinc oxides, nickel oxide, copper oxide, and varieties of metals and metal/dielectric combinations.

This Special Issue devoted to low-dimensional materials will focus on the most recent advances in the development of electrical and optical devices and systems for biochemical and neurobiological sensing and will be composed of research articles, communications, reviews, and perspectives.

Prof. Dr. Zingway Pei
Guest Editor

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Keywords

  • 2D materials
  • metal oxide
  • metal nanostructures
  • biochemical
  • volatile organic compounds
  • resistive-type sensors
  • optical sensors
  • bioelectronics and biophotonics

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Published Papers (3 papers)

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Research

14 pages, 36650 KiB  
Communication
An Innovative Simple Electrochemical Levofloxacin Sensor Assembled from Carbon Paste Enhanced with Nano-Sized Fumed Silica
by Amany M. Fekry
Biosensors 2022, 12(10), 906; https://doi.org/10.3390/bios12100906 - 21 Oct 2022
Cited by 14 | Viewed by 2264
Abstract
A new electrochemical sensor for the detection of levofloxacin (LV) was efficiently realized. The aim was to develop a new, cheap, and simple sensor for the detection of LV, which is used in various infections due to its pharmacological importance. It consists of [...] Read more.
A new electrochemical sensor for the detection of levofloxacin (LV) was efficiently realized. The aim was to develop a new, cheap, and simple sensor for the detection of LV, which is used in various infections due to its pharmacological importance. It consists of carbon paste (CP) enhanced with nano-sized fumed silica (NFS). NFS has a very low bulk density and a large surface area. The carbon paste-enhanced NFS electrode (NFS/CPE) showed great electrocatalytic activity in the oxidation of 1.0 mM LV in Britton–Robinson buffer (BR) at pH values ranging from 3.0 to 8.0. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used; the peak current value (Ip) of the NFS/CPE sensor was 2.7 times that of the bare electrode, ensuring its high electrocatalytic activity. Electrochemical impedance spectroscopy (EIS) was performed at a peak potential (Ep) of +1066 mV, yielding a resistance of 10 kΩ for the designed NFS/CPE sensor compared to 2461 kΩ for the bare electrode, indicating the high conductivity of the modified sensor and verifying the data observed using the CV technique. Surface descriptions were determined by scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX). The variation in the concentration of LV (2.0 to 1000 µM) was considered in BR buffer (pH = 5.0) at a scan rate (SR) of 10 mV/s by the NFS/CPE. The detection and quantification limits were 0.09 µM and 0.30 µM, respectively. To evaluate the application of LV in real samples, this procedure was established on Quinostarmax 500 mg tablets and human plasma samples. Reasonable results were obtained for the detection of LV. Full article
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9 pages, 45906 KiB  
Communication
Room-Temperature Synthesis of Air-Stable Near-Infrared Emission in FAPbI3 Nanoparticles Embedded in Silica
by Lung-Chien Chen, Li-Wei Chao, Chen-Yu Xu, Chih-Hung Hsu, Yi-Ting Lee, Zi-Min Xu, Chun-Cheng Lin and Zong-Liang Tseng
Biosensors 2021, 11(11), 440; https://doi.org/10.3390/bios11110440 - 4 Nov 2021
Cited by 5 | Viewed by 3144
Abstract
Hybrid organic−inorganic and all-inorganic metal halide perovskite nanoparticles (PNPs) have shown their excellent characteristics for optoelectronic applications. We report an atmospheric process to embed formamidinium CH(NH2)2PbI3 (FAPbI3) PNPs in silica protective layer at room temperature (approximately [...] Read more.
Hybrid organic−inorganic and all-inorganic metal halide perovskite nanoparticles (PNPs) have shown their excellent characteristics for optoelectronic applications. We report an atmospheric process to embed formamidinium CH(NH2)2PbI3 (FAPbI3) PNPs in silica protective layer at room temperature (approximately 26 °C) employing (3-aminopropyl) triethoxysilane (APTES). The resulting perovskite nanocomposite (PNCs) achieved a high photoluminescence (PL) quantum yield of 58.0% and good stability under atmospheric moisture conditions. Moreover, the PNCs showed high PL intensity over 1 month of storage (approximately 26 °C) and more than 380 min of PNCs solutions in DI water. The studied near-infrared (NIR) light-emitting diode (LED) combined a NIR-emitting PNCs coating and a blue InGaN-based chip that exhibited a 788 nm electroluminescence spectrum of NIR-LEDs under 2.6 V. This may be a powerful tool to track of muscle and disabled patients in the detection of a blood vessel. Full article
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12 pages, 3942 KiB  
Article
Electrochemical Detection of Electrolytes Using a Solid-State Ion-Selective Electrode of Single-Piece Type Membrane
by Li-Da Chen, Wei-Jhen Wang and Gou-Jen Wang
Biosensors 2021, 11(4), 109; https://doi.org/10.3390/bios11040109 - 7 Apr 2021
Cited by 17 | Viewed by 5855
Abstract
This study aimed to develop simple electrochemical electrodes for the fast detection of chloride, sodium and potassium ions in human serum. A flat thin-film gold electrode was used as the detection electrode for chloride ions; a single-piece type membrane based solid-state ion-selective electrode [...] Read more.
This study aimed to develop simple electrochemical electrodes for the fast detection of chloride, sodium and potassium ions in human serum. A flat thin-film gold electrode was used as the detection electrode for chloride ions; a single-piece type membrane based solid-state ion-selective electrode (ISE), which was formed by covering a flat thin-film gold electrode with a mixture of 7,7,8,8-tetracyanoquinodimethane (TCNQ) and ion-selective membrane (ISM), was developed for sodium and potassium ions detection. Through cyclic voltammetry (CV) and square-wave voltammetry (SWV), the detection data can be obtained within two minutes. The linear detection ranges in the standard samples of chloride, sodium, and potassium ions were 25–200 mM, 50–200 mM, and 2–10 mM, with the average relative standard deviation (RSD) of 0.79%, 1.65%, and 0.47% and the average recovery rates of 101%, 100% and 96%, respectively. Interference experiments with Na+, K+, Cl, Ca2+, and Mg2+ ions demonstrated that the proposed detection electrodes have good selectivity. Moreover, the proposed detection electrodes have characteristics such as the ability to be prepared under relatively simple process conditions, excellent detection sensitivity, and low RSD, and the detection linear range is suitable for the Cl, Na+ and K+ concentrations in human serum. Full article
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