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Brain Sciences
Special Issues
Translational Neuroanatomy: Recent Updates and Future Perspectives
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Translational Neuroanatomy: Recent Updates and Future Perspectives

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurosurgery and Neuroanatomy".

Deadline for manuscript submissions: 15 February 2025 | Viewed by 4249

Special Issue Editor

Dr. Grzegorz Wysiadecki

E-Mail Website
Guest Editor
Department of Normal and Clinical Anatomy, Medical University Lodz, 90-419 Lodz, Poland
Interests: neuroanatomy; peripheral nerves; skull base; brain imaging; psychology; personality psychology; psychotraumatology

Special Issue Information

Dear Colleagues,

Translational research is based on an approach that aims to convert basic research results into practical applications. In biomedical sciences, this perspective is also referred to as bench to bedside. An essential aspect of translational research is that their outcomes generate scientific and operational innovations and, as a result, benefit clinical practice. This Special Issue aims to refer to the traditional research paradigm in reference to neuroanatomy as a broadly understood part of neuroscience. Thus, this Special Issue "Translational Neuroanatomy: Recent Updates and Future Perspectives" aims to enable researchers and authors to present a wide range of reports on the following topics:

  • New neuroanatomical concepts, especially neuroanatomical studies, based on new methods or new approaches;
  • Original research that may potentially change the direction of thinking about a specific issue or topic related to central or peripheral nervous system’s structure and function;
  • Basic and clinical research extending the existing knowledge on the nervous system in the context of clinical practice;
  • Neuroanatomical techniques used to study neuroanatomy.

High-quality original research papers, reviews, and meta-analyses on topics related to the structure and functioning of the brain and the nervous system are also welcome.

Dr. Grzegorz Wysiadecki
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neuroanatomy
  • clinical neuroscience
  • central or peripheral nervous system

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

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Research

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14 pages, 4453 KiB  
Article
Digital Image Analysis of Vertebral Body S1 and Its Ossification Center in the Human Fetus
by Magdalena Grzonkowska, Katarzyna Bogacz, Andrzej Żytkowski, Monika Szkultecka-Dębek, Michał Kułakowski, Michał Janiak, Agnieszka Rogalska and Mariusz Baumgart
Brain Sci. 2025, 15(1), 74; https://doi.org/10.3390/brainsci15010074 - 15 Jan 2025
Viewed by 548
Abstract
Objectives: The aim of the present study was to examine the growth dynamics of the first sacral vertebra and its ossification center in the human fetus, based on their linear, planar, and volumetric parameters. Methods: The examinations were carried out on 54 human [...] Read more.
Objectives: The aim of the present study was to examine the growth dynamics of the first sacral vertebra and its ossification center in the human fetus, based on their linear, planar, and volumetric parameters. Methods: The examinations were carried out on 54 human fetuses of both sexes (26 males and 28 females) aged 18–30 weeks of gestation, which had been preserved in 10% neutral formalin solution. Using CT, digital image analysis software, 3D reconstruction, and statistical methods, the size of the first sacral vertebra and its ossification center was evaluated. Results: The first sacral vertebra and its ossification center grew proportionately according to fetal weeks. Conclusions: The numerical data obtained from computed tomography and the growth patterns of the body of the first sacral vertebra and its ossification center may serve as age-specific normative intervals relevant for gynecologists, obstetricians, pediatricians, and radiologists during fetal ultrasound screening. Our findings on the growth of the body of the first sacral vertebra and its ossification center may be useful in daily clinical practice, particularly in ultrasonic monitoring of normal fetal growth and in screening for congenital defects and skeletal dysplasias. Full article
(This article belongs to the Special Issue Translational Neuroanatomy: Recent Updates and Future Perspectives)
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13 pages, 6448 KiB  
Article
Anatomical Study of the Inferior Oblique Muscle and Its Innervation: Morphometric Characteristics, Anatomical Variations, and Histological Evaluation of the Nerve to the Inferior Oblique Muscle
by Robert Haładaj, R. Shane Tubbs and Ivan Varga
Brain Sci. 2024, 14(9), 925; https://doi.org/10.3390/brainsci14090925 - 17 Sep 2024
Viewed by 1010
Abstract
Background: This report aims to supplement the existing knowledge on the inferior oblique muscle. In particular, this study presents detailed anatomical and histological data concerning the muscle’s entry point (or entry zone) of the nerve to the inferior oblique muscle. Particular attention was [...] Read more.
Background: This report aims to supplement the existing knowledge on the inferior oblique muscle. In particular, this study presents detailed anatomical and histological data concerning the muscle’s entry point (or entry zone) of the nerve to the inferior oblique muscle. Particular attention was paid to the topographical relationships of the nerve to the inferior oblique muscle (NTIO), including the location of its entry point to the muscle’s belly and its anatomical variations. Methods: Sixty orbits from cadaveric hemi-heads fixed in 10% formalin were studied. The course of the NTIO was traced along the lateral border of the inferior rectus muscle as far as its entry point to the inferior oblique muscle. Particular attention was paid to the various ways in which the NTIO’s muscular sub-branches penetrated between the fibers of the inferior oblique muscle. Results: Three types of NTIO entries to the inferior oblique muscle’s belly were distinguished. In the most common type (48.3%), the nerve entered the muscle’s inferior (orbital) surface. In the next most common type (36.7%), terminal muscular sub-branches of the NTIO joined the superior (also referred to as ocular or global) surface of the inferior oblique muscle. In the remaining four cases (15%), the terminal sub-branches of the NTIO were divided into two main groups (superior and inferior) that joined both the superior and inferior surfaces of the muscle. Histological examination confirmed that the distal part of the NTIO shows a characteristic arcuate course (angulation) just before reaching the muscle’s belly. The process for splitting and forming separate muscular sub-branches of the NTIO was observed for all the examined histological specimens at the level of the nerve’s angulation. Conclusions: The presented findings enhance the understanding of the anatomical variations and precise distribution of motor sub-branches reaching the inferior oblique muscle, which may deepen anatomical knowledge and potentially enhance the management of ocular motor disorders. Full article
(This article belongs to the Special Issue Translational Neuroanatomy: Recent Updates and Future Perspectives)
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Review

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16 pages, 5741 KiB  
Review
The Arterial Anatomy of the Cerebellum—A Comprehensive Review
by Malwina Błaszczyk, Kajetan Ochwat, Sandra Necka, Maria Kwiecińska, Patryk Ostrowski, Michał Bonczar, Andrzej Żytkowski, Jerzy Walocha, Jerzy Mituś and Mateusz Koziej
Brain Sci. 2024, 14(8), 763; https://doi.org/10.3390/brainsci14080763 - 29 Jul 2024
Cited by 2 | Viewed by 2170
Abstract
The cerebellum, a major feature of the hindbrain, lies posterior to the pons and medulla and inferior to the posterior part of the cerebrum. It lies beneath the tentorium cerebelli in the posterior cranial fossa and consists of two lateral hemispheres connected by [...] Read more.
The cerebellum, a major feature of the hindbrain, lies posterior to the pons and medulla and inferior to the posterior part of the cerebrum. It lies beneath the tentorium cerebelli in the posterior cranial fossa and consists of two lateral hemispheres connected by the vermis. The cerebellum is primarily supplied by three arteries originating from the vertebrobasilar system: the superior cerebellar artery (SCA), the anterior inferior cerebellar artery (AICA), and the posterior inferior cerebellar artery (PICA). However, variations of the cerebellar arteries may occur, such as duplication of the SCA, SCA creating a common trunk with the posterior cerebral artery, triplication of the AICA, and agenesis of PICA, amongst others. Knowledge of the arterial anatomy of the cerebellum is crucial, as inadequate blood supply to this region can result in diminished motor functioning, significantly impacting the quality of life for patients. The present study demonstrated the importance of adequate anatomical knowledge of the arteries supplying the cerebellum. The PubMed and Embase databases were searched to gather articles on the anatomical characteristics and variations of the arterial supply of the cerebellum. It is the most comprehensive and up-to-date review available in the literature. The possible variations of these vessels may be clinically silent or present with clinical symptoms such as neurovascular compression syndromes of the cranial nerves and aneurysms. With a comprehensive understanding of the cerebellar arterial system, physicians can enhance their diagnostic and treatment capabilities, ultimately leading to more effective management of cerebellar vascular-related issues and other neurological deficits. Full article
(This article belongs to the Special Issue Translational Neuroanatomy: Recent Updates and Future Perspectives)
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