Advances in Electrocochleography

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Systems Neuroscience".

Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 4750

Special Issue Editors


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Guest Editor
Otolaryngology Department, Università degli Studi di Siena, 53100 Siena, Italy
Interests: neurotology; hearing; neuromodulation

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Guest Editor
Division of Otology, Neurotology, and Cranial Base Surgery, The Ohio State University, College of Medicine, Columbus, OH 43210, USA
Interests: cochlear implant; otology; electrocochleography; vestibular schwannoma; single side deafness

Special Issue Information

Dear Colleagues,

[*] Background & history of this topic:

Electrocochleography was introduced in the clinical setting in 1947 from Lempert. Since then, the recording methodology of cochlear potentials has had ups and downs both in clinical and research applications over the last seven decades. Electrocochleography has been adopted widely in research and clinical settings to measure electrical potentials derived from the cochlea for the diagnosis of hearing loss, hydrops, and the monitoring of hearing preservation.

[*] Aim and scope of the special issue:

The main aim of this Special Issue is to expand the knowledge on electrocochleography, providing cutting-edge research and clinical studies and providing evidence-based reviews on the clinical application of electrocochleography.

[*] Cutting-edge research:

Electrocochleography has been adopted in the clinical setting to estimate auditory thresholds in difficult cases, such in infants and in the diagnosis on auditory neuropathy in children. Despite its early adoption in defining the presence of cochlear hydrops in Meniere’s disease, it was recently demonstrated to have a promising role in the intraoperative monitoring of hearing preservation and array insertion in cochlear implants. On a basic research level, it is a fundamental tool to study cochlear toxicity in experimental animals as well as the improvement of hearing related to new regenerative treatments.

[*] What kind of papers we are soliciting:

We are welcoming both clinical and basic science research papers on electrocochleography and evidence-based reviews on its clinical application.

Dr. Mandalà Marco
Dr. Oliver Adunka
Guest Editors

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Keywords

  • electrocochleography
  • hearing preservation
  • cochlear implant
  • Meniere’ disease
  • audiology
  • otology
  • cochlear potentials

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Published Papers (2 papers)

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Research

11 pages, 3314 KiB  
Article
Multi-Frequency Electrocochleography and Electrode Scan to Identify Electrode Insertion Trauma during Cochlear Implantation
by Aniket A. Saoji, Madison K. Graham, Weston J. Adkins, Kanthaiah Koka, Matthew L. Carlson, Brian A. Neff, Colin L. W. Driscoll and Douglas C. Fitzpatrick
Brain Sci. 2023, 13(2), 330; https://doi.org/10.3390/brainsci13020330 - 15 Feb 2023
Cited by 6 | Viewed by 1915
Abstract
Intraoperative electrocochleography (ECOG) is performed using a single low-frequency acoustic stimulus (e.g., 500 Hz) to monitor cochlear microphonics (CM) during cochlear implant (CI) electrode insertion. A decrease in CM amplitude is commonly associated with cochlear trauma and is used to guide electrode placement. [...] Read more.
Intraoperative electrocochleography (ECOG) is performed using a single low-frequency acoustic stimulus (e.g., 500 Hz) to monitor cochlear microphonics (CM) during cochlear implant (CI) electrode insertion. A decrease in CM amplitude is commonly associated with cochlear trauma and is used to guide electrode placement. However, advancement of the recording electrode beyond the sites of CM generation can also lead to a decrease in CM amplitude and is sometimes interpreted as cochlear trauma, resulting in unnecessary electrode manipulation and increased risk of cochlear trauma during CI electrode placement. In the present study, multi-frequency ECOG was used to monitor CM during CI electrode placement. The intraoperative CM tracings were compared with electrode scan measurements, where CM was measured for each of the intracochlear electrodes. Comparison between the peak CM amplitude measured during electrode placement and electrode scan measurements was used to differentiate between different mechanisms for decrease in CM amplitude during CI electrode insertion. Analysis of the data shows that both multi-frequency electrocochleography and electrode scan could potentially be used to differentiate between different mechanisms for decreasing CM amplitude and providing appropriate feedback to the surgeon during CI electrode placement. Full article
(This article belongs to the Special Issue Advances in Electrocochleography)
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11 pages, 1520 KiB  
Article
A Retrospective Evaluation to Assess Reliability of Electrophysiological Methods for Diagnosis of Hearing Loss in Infants
by Marco Mandalà, Luca Mazzocchin, Bryan Kevin Ward, Francesca Viberti, Ilaria Bindi, Lorenzo Salerni, Giacomo Colletti, Liliana Colletti and Vittorio Colletti
Brain Sci. 2022, 12(7), 950; https://doi.org/10.3390/brainsci12070950 - 20 Jul 2022
Cited by 2 | Viewed by 2376
Abstract
Background: An electrophysiological investigation with auditory brainstem response (ABR), round window electrocochleography (RW-ECoG), and electrical-ABR (E-ABR) was performed in children with suspected hearing loss with the purpose of early diagnosis and treatment. The effectiveness of the electrophysiological measures as diagnostic tools was assessed [...] Read more.
Background: An electrophysiological investigation with auditory brainstem response (ABR), round window electrocochleography (RW-ECoG), and electrical-ABR (E-ABR) was performed in children with suspected hearing loss with the purpose of early diagnosis and treatment. The effectiveness of the electrophysiological measures as diagnostic tools was assessed in this study. Methods: In this retrospective case series with chart review, 790 children below 3 years of age with suspected profound hearing loss were tested with impedance audiometry and underwent electrophysiological investigation (ABR, RW-ECoG, and E-ABR). All implanted cases underwent pure-tone audiometry (PTA) of the non-implanted ear at least 5 years after surgery for a long-term assessment of the reliability of the protocol. Results: Two hundred and fourteen children showed bilateral severe-to-profound hearing loss. In 56 children with either ABR thresholds between 70 and 90 dB nHL or no response, RW-ECoG showed thresholds below 70 dB nHL. In the 21 infants with bilateral profound sensorineural hearing loss receiving a unilateral cochlear implant, no statistically significant differences were found in auditory thresholds in the non-implanted ear between electrophysiological measures and PTA at the last follow-up (p > 0.05). Eight implanted children showed residual hearing below 2000 Hz worse than 100 dB nHL and 2 children showed pantonal residual hearing worse than 100 dB nHL (p > 0.05). Conclusion: The audiological evaluation of infants with a comprehensive protocol is highly reliable. RW-ECoG provided a better definition of hearing thresholds, while E-ABR added useful information in cases of auditory nerve deficiency. Full article
(This article belongs to the Special Issue Advances in Electrocochleography)
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