Research on Bio-Behavioral Signatures of Neurodevelopmental Disorders

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Developmental Neuroscience".

Deadline for manuscript submissions: closed (15 March 2024) | Viewed by 2659

Special Issue Editors


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Guest Editor
MoDyCo, UMR 7114 CNRS, Université Paris Nanterre, 92000 Nanterre, France
Interests: EEG; dyslexia; ADHD; eye tracker; posture; ASD
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Guest Editor
MoDyCo, UMR 7114 CNRS, Université Paris Nanterre, 92000 Nanterre, France
Interests: dyslexia

Special Issue Information

Dear Colleagues,

The number of subjects with neurodevelopmental deficits (autism, dyslexia, TOC, ADHD, schizophrenia, etc.) is increasing. Such disorders have a negative impact on social lives; children report difficulties at school, in learning, and adults have difficulties in working and find good and permanent jobs.

This Special Issue of Brain Sciences aims to provide a collection of studies that highlight the most recent advancements in the field of neurodevelopment disorder research and prevention. Particular interest will be focused on biomarkers that could help the diagnoses of such pathologies. We invite authors to submit research studies with different techniques (imaging, eye-tracking, EEG, fMRI, and posture/gait). Additionally, studies showing different types of training/adaptive mechanisms that are useful for these disorders are of interest.

Dr. Maria Pia Bucci
Prof. Dr. Frédéric Isel
Guest Editors

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Keywords

  • neurodevelopmental disorders
  • autism
  • dyslexia
  • TOC
  • ADHD
  • schizophrenia

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Published Papers (2 papers)

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Research

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21 pages, 1213 KiB  
Article
Online Indicators of Written Production: ‘Bio-Behavioural’ Markers of Dyslexia–Dysorthographia?
by Audrey Mazur and Matthieu Quignard
Brain Sci. 2024, 14(11), 1125; https://doi.org/10.3390/brainsci14111125 - 7 Nov 2024
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Abstract
Dyslexia–dysorthographia is a neurodevelopmental disorder in which the symptoms appear during the person’s development (generally around the age of 7 or 8) and persist throughout life. The study of this written language disorder mainly focuses on children, principally in the clinical, cognitive science [...] Read more.
Dyslexia–dysorthographia is a neurodevelopmental disorder in which the symptoms appear during the person’s development (generally around the age of 7 or 8) and persist throughout life. The study of this written language disorder mainly focuses on children, principally in the clinical, cognitive science and neuroscience fields. The importance and originality of this study are that it investigates the impact of dyslexia–dysorthographia on written production in young adults (students) with dyslexia, from a psycholinguistic perspective. To do this, students and matched-control individuals were asked to produce written texts on the same theme. These productions were then analysed, observing on-line indicators, such as pause location and duration. The current investigation found that students with dyslexia still have important difficulties with writing and their lack of automation in spelling has consequences on the transcription and planning process: although they have the same handwriting speed, pressure and word rate as control students, they make longer pauses before words, especially before short and long words, words involving grammatical inflexion, grammatical words and punctuation. Full article
(This article belongs to the Special Issue Research on Bio-Behavioral Signatures of Neurodevelopmental Disorders)
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29 pages, 1100 KiB  
Systematic Review
Investigating Dyslexia through Diffusion Tensor Imaging across Ages: A Systematic Review
by Bruce Martins, Mariana Yumi Baba, Elisa Monteiro Dimateo, Leticia Fruchi Costa, Aila Silveira Camara, Katerina Lukasova and Mariana Penteado Nucci
Brain Sci. 2024, 14(4), 349; https://doi.org/10.3390/brainsci14040349 - 31 Mar 2024
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Abstract
Dyslexia is a neurodevelopmental disorder that presents a deficit in accuracy and/or fluency while reading or spelling that is not expected given the level of cognitive functioning. Research indicates brain structural changes mainly in the left hemisphere, comprising arcuate fasciculus (AF) and corona [...] Read more.
Dyslexia is a neurodevelopmental disorder that presents a deficit in accuracy and/or fluency while reading or spelling that is not expected given the level of cognitive functioning. Research indicates brain structural changes mainly in the left hemisphere, comprising arcuate fasciculus (AF) and corona radiata (CR). The purpose of this systematic review is to better understand the possible methods for analyzing Diffusion Tensor Imaging (DTI) data while accounting for the characteristics of dyslexia in the last decade of the literature. Among 124 articles screened from PubMed and Scopus, 49 met inclusion criteria, focusing on dyslexia without neurological or psychiatric comorbidities. Article selection involved paired evaluation, with a third reviewer resolving discrepancies. The selected articles were analyzed using two topics: (1) a demographic and cognitive assessment of the sample and (2) DTI acquisition and analysis. Predominantly, studies centered on English-speaking children with reading difficulties, with preserved non-verbal intelligence, attention, and memory, and deficits in reading tests, rapid automatic naming, and phonological awareness. Structural differences were found mainly in the left AF in all ages and in the bilateral superior longitudinal fasciculus for readers-children and adults. A better understanding of structural brain changes of dyslexia and neuroadaptations can be a guide for future interventions. Full article
(This article belongs to the Special Issue Research on Bio-Behavioral Signatures of Neurodevelopmental Disorders)
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