Hydrogen Bonding Activation

A special issue of Catalysts (ISSN 2073-4344).

Deadline for manuscript submissions: closed (30 September 2018) | Viewed by 7181

Special Issue Editor


E-Mail Website
Guest Editor
Laboratorio de Organocatálisis Asimétrica, Departamento de Química Orgánica, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH) CSIC-Universidad de Zaragoza, C/Pedro Cerbuna 12, 50009 Zaragoza, Spain
Interests: asymmetric catalysis; biological properties; cinchona; computational calculations; hydrogen bond; mechanistic studies; natural products; organic synthesis; phase transfer catalysts; squaramides; (thio)ureas
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

With the continuous efforts made by many research groups, a remarkable development of the asymmetric organocatalysis has been achieved in the last years. This discipline represents a complementary alternative to the most broadly explored metal and enzyme catalysis. The immense number of organocatalytic processes could be classified into four large groups depending on the nature of the catalytic activation and, among them, hydrogen-bond catalysis represents a significant contribution into this large area. Catalysts such as thiourea/urea derivatives, squaramides, guanidines, BINOL analogs, chiral phosphoric acid derivatives or other already known or new structures acting through hydrogen bonding will be collected in this special issue. Even metal catalysts or metal-organocatalysts, where hydrogen bonds have been also proposed as the key mode of activation, have room in this issue.

Prof. Dr. Raquel P. Herrera
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Bidentate activation
  • Brønsted acid
  • Dual catalysis
  • Hydrogen bonding
  • Lewis acid
  • Mechanistic studies
  • Monodentate activation

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

21 pages, 10682 KiB  
Article
Urea Activation by an External Brønsted Acid: Breaking Self-Association and Tuning Catalytic Performance
by Isaac G. Sonsona, Eugenia Marqués-López, Marleen Häring, David Díaz Díaz and Raquel P. Herrera
Catalysts 2018, 8(8), 305; https://doi.org/10.3390/catal8080305 - 28 Jul 2018
Cited by 6 | Viewed by 6223
Abstract
In this work, we hypothesize that Brønsted acids can activate urea-based catalysts by diminishing its self-assembly tendency. As a proof of concept, we used the asymmetric Friedel–Crafts alkylation of indoles with nitroalkenes as a benchmark reaction. The resulting 3-substituted indole derivatives were obtained [...] Read more.
In this work, we hypothesize that Brønsted acids can activate urea-based catalysts by diminishing its self-assembly tendency. As a proof of concept, we used the asymmetric Friedel–Crafts alkylation of indoles with nitroalkenes as a benchmark reaction. The resulting 3-substituted indole derivatives were obtained with better results due to cooperative effects of the chiral urea and a Brønsted acid additive. Such synergy has been rationalized in terms of disassembly of the supramolecular catalyst aggregates, affording a more acidic and rigid catalytic complex. Full article
(This article belongs to the Special Issue Hydrogen Bonding Activation)
Show Figures

Graphical abstract

Back to TopTop