Cell Adhesion/Migration in Tumor Metastasis
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Motility and Adhesion".
Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 2390
Special Issue Editor
Interests: cell adhesion; integrin; late endosomes; cell signaling; hippo pathway; osteoblast; bone
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cell migration plays a critical role in many physio-pathological processes, including cancer progression. Tumour metastasis is a deadly consequence of tumour cell invasion and dissemination. In addition, 2D cell migration in specific extracellular matrixes typically relies on the formation of protrusions, mechanosensitive cell attachment to the ECM, actin-based force generation to propel cell movement and finally, adhesion disassembly at the cell rear. Following the in-depth study of the key steps of the process, new regulatory pathways and accessory proteins are emerging. At the same time, the availability of new tools to address how the cells move in a 3D environment is adding to the complexity of how this coordinated event has to be regulated. The aim of this Special Issue is to compile original and review articles that deal with cell invasion and migration in 2D as well as 3D. Work that presents new innovative technical approaches or protein functions related to this process is very welcome.
Dr. Daniel Bouvard
Guest Editor
Manuscript Submission Information
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Keywords
- cell adhesion
- invasion
- migration
- extracellular matrix
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