Cervical Cancer: From Molecular and Cellular Mechanisms to Therapeutic Opportunities
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Reproductive Cells and Development".
Deadline for manuscript submissions: closed (1 April 2022) | Viewed by 8613
Special Issue Editors
Interests: ovarian cancer; cervical cancer; endometrial cancer; vulvar cancer; vagina cancer; gestational trophoblastic disease
Interests: ovarian cancer; target therapies; chemotherapy; homologous recombination; BRCA; platinum resistance; PARP inhibitors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cervical cancer is a malignant tumor and is the fourth most common cancer among women worldwide. Since the introduction of angiogenesis inhibitors, treatment for recurrent and advanced cervical cancers has improved in the past five years, but overall survival is still poor.
Therefore, several areas of cervical cancer research continue to address the challenges of identifying appropriate therapeutic alternatives. With this regard, exploration of pathogenesis and molecular mechanism of cervical cancer is pivotal; moreover, also the knowledge of immune system adaption in affected patients is essential, as the local immune response is considered a key determinant in cervical carcinogenesis after persistent infection with oncogenic, high-risk human papillomavirus (HPV) infections. Multifactorial etiology of cervical cancer requires a combined approach, involving many disciplines, from molecular genetics, to immunotherapy and beyond…
For this Special Issue, we welcome basic translational, professional opinions, and reviews in the broad field of cervical cancer. Our goal is to use this information collected to improve cervical cancer management in the future but also to help researchers in designing new trials with personalized therapeutic strategies for patients affected by cervical cancer.
Dr. Domenica Lorusso
Guest Editor
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Keywords
- cervical cancer
- carcinogenesis
- genetic
- vaccination
- immunecheckpoint inhibitor
- molecular mechanism
- molecular biomarkers
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