Eosinophils and Their Role in Allergy and Related Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 664
Special Issue Editor
Interests: allergy; immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Eosinophils are enigmatic cells whose functional role within the immune system is still under intense scrutiny, and this has led to a greater appreciation of the contribution of eosinophils to allergy and related diseases. Understanding their function in these diseases has become especially pertinent since the introduction of highly successful anti-eosinophil biologic therapies to treat eosinophil-associated allergic diseases. In this Special Issue, we extend our understanding of the role of eosinophils in allergy, asthma, and related diseases. How eosinophils become elevated and activated, and the factors required for their proliferation and release of inflammatory mediators in allergies, are topics of interest in this collection of articles. I therefore welcome review and original research articles that are focused on the role of eosinophils in this domain. These articles should describe the function of eosinophils in allergic inflammation and how these may be modified by therapies such as anti-eosinophil biologics. Articles should also focus on feasible drug targets to regulate the number and activity of eosinophils in allergic diseases.
Prof. Dr. Paige Lacy
Guest Editor
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Keywords
- eosinophils
- asthma
- allergy
- inflammation
- anti-eosinophil biologics
- interleukin-5
- interleukin-5 receptor
- degranulation
- mediator release
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