Extracellular Vesicles’ Role in Disease Progression, Diagnosis, and Therapy
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 15616
Special Issue Editor
Special Issue Information
Dear Colleagues,
The field of extracellular vesicles (EVs) has captured the interest of many scientists in recent years. However, despite our growing knowledge about EVs, the roles they play in health and disease continue to keep us fascinated. The role of EVs as an intercellular communication mode expands every day with no exaggeration, and in a wide spectrum of diseases. EVs play a role in various diseases, such as thrombosis–haemostasis complication and cardiovascular diseases, cancers, kidney diseases, metabolic diseases, neurodegenerative diseases, lung diseases, and others. Additionally, we now know that bacteria shedding EVs that mimic the immunological response the bacteria provoke. Herein, we include EV subtypes such as microvesicles, microparticles, exosomes, oncosomes, ectosomes, etc.
The EV content of proteins, mRNAs, miRNAs, and DNA, and their existence in all body fluids makes them an ideal tool to look for biomarkers for various diseases. EVs are a very promising tool for future diagnostics, because they provide simple non-invasive procedures for disease diagnosis. Moreover, they may provide a simple tool to monitor disease progression in an almost real-time fashion. EVs will play a major role in the initiative of liquid biopsy. Further, the therapeutic potential of EVs is another interesting issue, which may surprise us in the near future.
This Special Issue aims to serve as your forum to enrich the field of EVs. You can contribute with your valuable work in any field mentioned in this short introduction. Let us shed some light on EV roles in various diseases and biological functions.
Dr. Khalid Al-Nedawi
Guest Editor
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Keywords
- extracellular vesicles
- exosomes
- microvesicles
- biomarkers
- disease progression
- therapeutic potential
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