Vascular Growth Factors in Health and Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (15 November 2023) | Viewed by 2604
Special Issue Editors
Interests: angiogenesis; signal transduction; cardiovascular diseases
Special Issue Information
Dear Colleagues,
Vascular endothelial growth factors (VEGFs) play a central role in regulating physiological angiogenesis. However, in several pathological conditions, such as in cancer, in cardiovascular diseases and in retinopathy, the physiological and protective role of VEGs could deviate and become deleterious, inducing the increased permeability of the endothelium, decreased inhibition of pro-apoptotic proteins and activation of inflammation. Anti-VEGF therapy strategies have been developed and approved for clinical use in cancer and retinopathy, but at the moment, anti-VEGF treatments require careful patient selection and monitoring. In addition, sometimes they fail to promote appropriate beneficial adaptive responses. The present Special Issue of Cell aims to summarize some of the latest advances in understanding the role of VEGFs in cancer, cardiovascular diseases and retinopathies, focusing on the involved cellular pathways, neuroinflammation and signaling pathways. We also welcome manuscripts that address therapeutic strategies in this field. For this purpose, we are encouraging basic and clinical researchers to present their valuable work as a scientific contribution or review articles. We would appreciate your contribution, and it will be a pleasure for us to receive your manuscripts. Our aim is to provide a comprehensive update on the role of VEGFs in disease and on their therapy options.
Dr. Silvana Balzan
Dr. Rosario Amato
Guest Editors
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