Stem Cells and Beyond: Innovations in Tissue Repair and Regeneration

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".

Deadline for manuscript submissions: 15 July 2025 | Viewed by 100

Special Issue Editor


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Guest Editor
Centre for Nanotechnology and Regenerative Medicine, Division of Surgery & Interventional Science, University College of London, London NW3 2QG, UK
Interests: regenerative surgery; fat grafting; adipose-derived stem cells; stromal vascular fraction; platelet rich plasma; exosomes; cytokines; growth factors; polynucleotides; fibrosis; scar; inflammation; wound healing; ageing

Special Issue Information

Dear Colleagues,

Regenerative medicine has emerged as a transformative field, offering promising solutions for tissue repair and regeneration across a wide range of conditions, including those resulting from injury, aging, or degenerative diseases.

Stem cells, including Adipose-Derived Stem Cells (ADSCs), Mesenchymal Stem Cells (MSCs), and induced Pluripotent Stem Cells (iPSCs), have shown great potential due to their capacity for multilineage differentiation and their ability to influence the tissue microenvironment through the release of bioactive molecules. These cells and their secretomes—such as cytokines, growth factors, and extracellular matrix components—play crucial roles in modulating cellular behavior and promoting tissue regeneration. In addition to cell-based therapies, there is growing interest in regenerative treatments that rely on the secretome, such as Platelet-Rich Plasma (PRP), exosomes, and polynucleotides. These treatments harness the regenerative power of bioactive molecules to stimulate tissue regeneration without the need for live cells.

This Special Issue, titled “Stem Cells and Beyond: Innovations in Tissue Repair and Regeneration”, highlights the latest advancements in cell therapies, as well as emerging applications of regenerative treatments such as Platelet-Rich Plasma (PRP), exosomes, and polynucleotides, for tissue regeneration.

By exploring novel strategies that combine stem-cell-based therapies with biomolecular signaling, this Special Issue aims to foster new insights into tissue regeneration strategies over a broad array of clinical applications, from wound healing to organ repair and beyond.

Yours faithfully,

Dr. Aurora Almadori
Guest Editor

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Keywords

  • adipose-derived stem cells
  • mesenchymal stem cells
  • induced pluripotent stem cells
  • stromal vascular fraction
  • platelet-rich plasma
  • exosomes
  • polynucleotides
  • cytokines
  • growth factors
  • extracellular matrix
  • cell signaling
  • wound healing
  • ageing
  • immune response
  • inflammation
  • scarring

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Published Papers

This special issue is now open for submission.
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