Head and Neck Squamous Cell Carcinomas: Biomarkers and Cellular Mechanisms towards a Precision Therapy
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Methods".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 2521
Special Issue Editor
2. Department of Otorhinolaryngology, Head & Neck Surgery, Maastricht University Medical Centre+, Maastricht, The Netherlands
Interests: head and neck neoplasms; laryngeal neoplasms; salivary gland tumors; digital pathology; laryngology; cancer immunology; biostatistics; melanoma; cutaneous oncology; immunotherapy
Special Issue Information
Dear Colleagues,
Head and neck squamous cell carcinoma (HNSCC) is the seventh most prevalent cancer worldwide, characterized by a relatively worse prognosis and the adverse impact of treatments on patients' quality of life. Apart from surgery and radiotherapy, there are only a few available systemic treatments, primarily involving platinum-based chemotherapy or cetuximab. Immunotherapy, a novel therapeutic approach, is currently limited to palliative care for cases of recurrent, unresectable, or metastatic disease. Consequently, the exploration of new biomarkers or potentially targetable mechanisms holds significant importance. The identification of subgroups of patients that could benefit from a de-intensified treatment regimen is also of paramount importance, aimed at a precision therapy reducing the tremendous toxicity of the current treatment modalities for HNSCC.
This Special Issue of Cells is focused on the latest advances and future trends in cellular, molecular, and biomarker research in the field of head and neck cancer. This Special Issue will include both original research articles as well as up-to-date review papers.
Dr. Francesco Missale
Guest Editor
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Keywords
- head and neck cancer
- biomarkers
- prognosis
- precision therapy
- immunotherapy
- translational research
- immune contexture
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