Cell-Based Cardiovascular Tissue Engineering and Therapies
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 385
Special Issue Editors
Interests: cardiovascular tissue engineering; 3D bioprinting; nano-biomaterials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Heart disease remains the leading cause of mortality and morbidity worldwide. Adult mammalian heart cannot repair by itself post injury due to the diminished capacity of cardiomyocytes to proliferate. Therefore, the loss of cardiomyocytes due to injuries is typically replaced by fibrotic scar, which contributes to the development of heart failure and arrhythmia. A variety of scaffold (biomaterial)-based, cell-based, and hybrid (cell and biomaterial) methods of tissue engineering have been devised and tested to enhance cardiac repair and regeneration following injuries. Among these, (stem) cell tissue engineering and therapies are at the forefront of current research in the treatment of various heart diseases. This Special Issue focuses on the latest development in the variety of cell/stem-cell-based tissue engineering strategies used to recapitulate the heart tissue in vitro, or as regenerative therapies in vivo. Topics of interest include tissue engineering based on pluripotent stem cells, cell and organoid models for cardiovascular disease modeling, paracrine mechanisms, cardiovascular tissue biomanufacturing techniques (e.g., 3D bioprinting), and cell- and tissue-based regenerative therapies (e.g., cardiac patch systems) for cardiovascular diseases.
Dr. Vahid Serpooshan
Dr. Wuqiang Zhu
Guest Editors
Manuscript Submission Information
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Keywords
- heart
- cardiovascular tissue engineering
- cell therapy
- bioengineering
- bioprinting
- organoid
- disease modeling
- cardiac regeneration
- induced pluripotent stem cells
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