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Feature Paper Collection in 'Surface Coatings for Biomedicine and Bioengineering'
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Feature Paper Collection in 'Surface Coatings for Biomedicine and Bioengineering'

A topical collection in Coatings (ISSN 2079-6412). This collection belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Viewed by 18757

Editor

Prof. Dr. Anton Ficai

E-Mail Website
Collection Editor
1. Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gh. Polizu St., 011061 Bucharest, Romania
2. Academy of Romanian Scientists, 54 Splaiul Independenței St., Bucharest, Romania
Interests: bio(nano)materials; synthesis methods; materials processing and design; advanced coatings; tissue engineering; drug delivery; characterization methods
Special Issues, Collections and Topics in MDPI journals

Topical Collection Information

Dear Colleagues,

As Editor-in-Chief of the Section “Surface Coatings for Biomedicine and Bioengineering”, I am excited to announce a Special Feature Paper Collection for this section. I would like to invite leading experts in the field to contribute high quality papers to this collection. This Feature Paper Collection aims to present novel approaches, improvements, or new cutting-edge developments in the field of surface coatings for biomedicine and bioengineering.

The particular areas of interest for this Topical Collection include but are not limited to:

  • Design and processing of coatings
  • Biomimetic approaches for tuning surface characteristics
  • Particularities in coating characterization
  • Tuning the properties and performances of medical devices according with the nature and deposition parameters of the coatings

Feature articles and reviews from top experts are welcome. We are happy to offer discount of 20% on the APCs for any article published, with additional discounts available if the contribution is a review that might be of great interest in this field. The criteria mainly include the academic background of the scholar, the publication record, the novelty and significance of content, and the peer-review results of the paper.

In addition, if 10 or more papers are published in this collection, we will make a collection book, and the leading authors of each article will receive a hard copy of this book.

Prof. Dr. Anton Ficai
Collection Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (8 papers)

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2024

Jump to: 2021, 2020

20 pages, 7211 KiB  
Article
Ceria-Stabilized Zirconia/Alumina Nanocomposite (NANO-Zr) Surface Enhances Osteogenesis Through Regulation of Macrophage Polarization
by Yuan Tian, Yunjia Song, Suli Lan, Ruoting Geng, Muxiang Wang, Sanwen Li, Jianmin Han, Hong Bai, Guang Hong and Ying Li
Coatings 2024, 14(11), 1460; https://doi.org/10.3390/coatings14111460 - 17 Nov 2024
Viewed by 377
Abstract
Zirconia implants are recognized for their excellent biocompatibility, aesthetics, and favorable mechanical properties. However, the effects of zirconia surfaces on osteogenesis, particularly in the presence of macrophages, are still not well understood. This study compares two types of zirconia surfaces—ceria-stabilized zirconia/alumina nanocomposite (NANO-Zr) [...] Read more.
Zirconia implants are recognized for their excellent biocompatibility, aesthetics, and favorable mechanical properties. However, the effects of zirconia surfaces on osteogenesis, particularly in the presence of macrophages, are still not well understood. This study compares two types of zirconia surfaces—ceria-stabilized zirconia/alumina nanocomposite (NANO-Zr) and 3 mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP)—with titanium (Ti) substrates. Both zirconia surfaces promoted macrophage adhesion and proliferation, facilitated a shift from M1 to M2 polarization, and created an immune microenvironment conducive to osteogenesis by downregulating IL-6 and TNF-α and upregulating IL-10 and TGF-β gene expression. In macrophage co-cultures, both zirconia surfaces also supported osteoblast adhesion and proliferation, with NANO-Zr notably enhancing osteogenic differentiation and mineralization. These results highlight NANO-Zr as a promising candidate for future dental and orthopedic implant applications. Full article
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15 pages, 9882 KiB  
Article
Coated Biodegradable Zinc Lithium Alloys: Development and Characterization of Co-Doped Strontium Copper Tricalcium Phosphate Coating for Antimicrobial Applications
by Julietta V. Rau, Angela De Bonis, Mariangela Curcio, Katia Barbaro, Marco Fosca, Inna V. Fadeeva, Giovana Collombaro Cardoso, Roberto Teghil, Tatiana K. Slonskaya and Yufeng Zheng
Coatings 2024, 14(8), 1073; https://doi.org/10.3390/coatings14081073 - 22 Aug 2024
Viewed by 842
Abstract
Zinc biodegradable implants represent a revolutionary advancement in medical technology, offering a promising alternative to titanium and stainless-steel implants and avoiding the need for secondary surgeries for removal. In this study, we aimed to fulfil the clinical demand for biodegradable implant materials by [...] Read more.
Zinc biodegradable implants represent a revolutionary advancement in medical technology, offering a promising alternative to titanium and stainless-steel implants and avoiding the need for secondary surgeries for removal. In this study, we aimed to fulfil the clinical demand for biodegradable implant materials by applying a coating of double-doped strontium and copper resorbable tricalcium phosphate (SrCu-TCP) onto a zinc-lithium (Zn-Li) biodegradable alloy using the Pulsed Laser Deposition method. The coated surfaces were thoroughly characterized using X-ray Diffraction, Fourier Transform Infrared Spectroscopy, Atomic Force Microscopy, and Scanning Electron Microscopy coupled with Energy Dispersive X-ray. Microbiology experiments were conducted to assess the inhibitory effects on the growth of various bacteria strains, including gram-positive Staphylococcus aureus and Enterococcus faecalis, gram-negative Pseudomonas aeruginosa and Escherichia coli, as well as the fungus Candida albicans. The obtained results showed that the roughness of the Zn-Li alloy increased from 91.8 ± 29.4 to 651.0 ± 179.5 nm when coated with SrCu-TCP. The thickness of the coating ranged between 3–3.5 µm. The inhibition of growth for all four bacteria strains and the fungus was in the range of 24–35% when cultured on SrCu-TCP coated Zn-Li samples. These findings suggest that the developed coatings are promising candidates for applications requiring inhibition of microorganisms. Full article
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16 pages, 5250 KiB  
Article
The Evaluation of the Cytotoxicity and Corrosion Processes of Porous Structures Manufactured Using Binder Jetting Technology from Stainless Steel 316L with Diamond-like Carbon Coating
by Dorota Laskowska, Katarzyna Mitura, Błażej Bałasz, Piotr Wilczek, Aneta Samotus, Witold Kaczorowski, Jacek Grabarczyk, Lucie Svobodová, Totka Bakalova and Stanisław Mitura
Coatings 2024, 14(8), 1018; https://doi.org/10.3390/coatings14081018 - 11 Aug 2024
Viewed by 1146
Abstract
With the growing interest in additive manufacturing technology, assessing the biocompatibility of manufactured elements for medical and veterinary applications has become crucial. This study aimed to investigate the corrosion properties and cytotoxicity of porous structures designed to enhance the osseointegration potential of implant [...] Read more.
With the growing interest in additive manufacturing technology, assessing the biocompatibility of manufactured elements for medical and veterinary applications has become crucial. This study aimed to investigate the corrosion properties and cytotoxicity of porous structures designed to enhance the osseointegration potential of implant surfaces. The structures were fabricated using BJ technology from 316L stainless steel powder, and their surfaces were modified with a DLC coating. The studies carried out on porous metal samples with and without DLC coatings demonstrated low cytotoxicity. However, no significant differences were found between the uncoated and DLC-coated samples, likely due to variations in the thickness of the coating on the porous samples and the occurrence of mechanical damage. Full article
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14 pages, 12915 KiB  
Article
Decoration of a Glass Surface with AgNPs Using Thio-Derivates for Environmental Applications
by Cornelia-Ioana Ilie, Angela Spoială, Ludmila Motelica, Liliana Marinescu, Georgiana Dolete, Doina-Roxana Trușcă, Ovidiu-Cristian Oprea, Denisa Ficai and Anton Ficai
Coatings 2024, 14(1), 96; https://doi.org/10.3390/coatings14010096 - 11 Jan 2024
Cited by 1 | Viewed by 1635
Abstract
The aim of this study is to decorate a glass surface with silver nanoparticles (AgNPs) and further prove its efficiency in the removal of some thio-derivatives—potential pollutants from water. Therefore, grafting the surface of glass-based platforms with AgNPs will strongly influence their interaction [...] Read more.
The aim of this study is to decorate a glass surface with silver nanoparticles (AgNPs) and further prove its efficiency in the removal of some thio-derivatives—potential pollutants from water. Therefore, grafting the surface of glass-based platforms with AgNPs will strongly influence their interaction with other substances or molecules. The most commonly used molecules for glass-based platform functionalization/modification are organosilanes. In this case, the main interest is in thioalkyl organosilanes because, after silanization, the thio (-SH) functional groups that have a high affinity for AgNPs can intermediate their binding on the surface. By decorating the glass platforms with AgNPs, these surfaces become active for the adsorption of dyes from wastewater. Certainly, in this case, the dyes must bear -SH groups to ensure a high affinity for these surfaces. Therefore, the desired purpose of this study was to develop glass-based platforms decorated with AgNPs able to bind model molecules—dyes from aqueous media (dithizone—DIT and thioindigo—TIO), with these platforms being potentially used for environmental applications. Full article
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2021

Jump to: 2024, 2020

14 pages, 1928 KiB  
Article
Effect of Micelle Encapsulation on Toxicity of CdSe/ZnS and Mn-Doped ZnSe Quantum Dots
by Qirui Fan, Abhilasha Dehankar, Thomas K. Porter and Jessica O. Winter
Coatings 2021, 11(8), 895; https://doi.org/10.3390/coatings11080895 - 26 Jul 2021
Cited by 4 | Viewed by 3202
Abstract
The optical properties of quantum dots (QD) make them excellent candidates for bioimaging, biosensing, and therapeutic applications. However, conventional QDs are comprised of heavy metals (e.g., cadmium) that pose toxicity challenges in biological systems. Synthesising QDs without heavy metals or introducing thick surface [...] Read more.
The optical properties of quantum dots (QD) make them excellent candidates for bioimaging, biosensing, and therapeutic applications. However, conventional QDs are comprised of heavy metals (e.g., cadmium) that pose toxicity challenges in biological systems. Synthesising QDs without heavy metals or introducing thick surface coatings, e.g., by encapsulation in micelles, can reduce toxicity. Here, we examined the toxicity of micelle encapsulated tetrapod-shaped Mn-doped ZnSe QDs, comparing them to 3-mercaptopropionic acid (MPA)-capped Mn-doped ZnSe QDs prepared by ligand exchange and commercial CdSe/ZnS QD systems that were either capped with MPA or encapsulated in micelles. HepG2 cell treatment with MPA-coated CdSe/ZnS QDs resulted in a dose-dependent reduction of viability (MTT assay, treatment at 0–25 μg/mL). Surprisingly, no reactive oxygen species (ROS) or apoptotic signaling was observed, despite evidence of apoptotic behavior in flow cytometry. CdSe/ZnS QD micelles showed minimal toxicity at doses up to 25 μg/mL, suggesting that thicker protective polymer layers reduce cytotoxicity. Despite their shape, neither MPA- nor micelle-coated Mn-doped ZnSe QDs displayed a statistically significant toxicity response over the doses investigated, suggesting these materials as good candidates for bioimaging applications. Full article
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13 pages, 5561 KiB  
Article
Ultrasonic Induced Refinement of Induction Heated Oxide Coating on Titanium
by Han Gao, Meijie Yu, Xin Chen, Guiyong Xiao, Chuanzhong Chen, Bing Liu and Yupeng Lu
Coatings 2021, 11(7), 812; https://doi.org/10.3390/coatings11070812 - 5 Jul 2021
Viewed by 2275
Abstract
Induction heating treatment (IHT) has recently been used to improve the bioactivity and biocompatibility of titanium and its alloys, greatly related to the formation of the nanoscale oxide coating. In this work, the effect of ultrasonic on the IHT oxidation behavior of pure [...] Read more.
Induction heating treatment (IHT) has recently been used to improve the bioactivity and biocompatibility of titanium and its alloys, greatly related to the formation of the nanoscale oxide coating. In this work, the effect of ultrasonic on the IHT oxidation behavior of pure titanium has been investigated. Ultrasonic-assisted IHT of pure titanium was carried out for 13, 20 and 25 s. Submicro-/nano-scale morphological coatings with rutile and anatase TiO2 were prepared on the surface of titanium substrates subjected to ultrasonic-assisted IHT. In particular, the TiO2 crystals were significantly refined by ultrasonic impact. An improvement in hydrophilicity and hardness of the oxide film was achieved by ultrasonic-assisted IHT. The refinement of TiO2 crystals is suggested to be caused by ultrasonic induced changes of energy, defect density and their correlation with diffusion of oxygen. The present study provides a potential method to refine the nanoscale oxide films on titanium substrates, which is promising for improving the wear resistance and bioactivity of titanium and its alloys. Full article
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13 pages, 2272 KiB  
Article
Fabrication and Characterization of Antimicrobial Magnetron Cosputtered TiO2/Ag/Cu Composite Coatings
by Dilyana Gospodonova, Iliana Ivanova and Todorka Vladkova
Coatings 2021, 11(4), 473; https://doi.org/10.3390/coatings11040473 - 17 Apr 2021
Cited by 4 | Viewed by 2741
Abstract
The aim of this study was to prepare TiO2/Ag/Cu magnetron co-sputtered coatings with controlled characteristics and to correlate them with the antimicrobial activity of the coated glass samples. The elemental composition and distribution, surface morphology, wettability, surface energy and its component [...] Read more.
The aim of this study was to prepare TiO2/Ag/Cu magnetron co-sputtered coatings with controlled characteristics and to correlate them with the antimicrobial activity of the coated glass samples. The elemental composition and distribution, surface morphology, wettability, surface energy and its component were estimated as the surface characteristics influencing the bioadhesion. Well expressed, specific, Ag/Cu concentration-dependent antimicrobial activity in vitro was demonstrated toward Gram-negative and Gram-positive standard test bacterial strains both by diffusion 21 assay and by Most Probable Number of surviving cells. Direct contact and eluted silver/coper nanoparticles killing were experimentally demonstrated as a mode of the antimicrobial action of the studied TiO2/Ag/Cu thin composite coatings. It is expected that they would ensure a broad spectrum bactericidal activity during the indwelling of the coated medical devices and for at least 12 h after that, with the supposition that the benefits will be over a longer time. Full article
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2020

Jump to: 2024, 2021

12 pages, 2609 KiB  
Article
Synthesis and Antibacterial Aspects of Graphitic C3N4@Polyaniline Composites
by Mohammad Oves, Mohammad Omaish Ansari, Reem Darwesh, Afzal Hussian, Mohamed F. Alajmi and Huda A. Qari
Coatings 2020, 10(10), 950; https://doi.org/10.3390/coatings10100950 - 1 Oct 2020
Cited by 23 | Viewed by 4003
Abstract
In this work, Pani and Pani@g-C3N4 was synthesized by in situ oxidative polymerization methodology of aniline, in the presence of g-C3N4. The as prepared Pani@g-C3N4 was characterized by scanning electron microscopy, transmission electron [...] Read more.
In this work, Pani and Pani@g-C3N4 was synthesized by in situ oxidative polymerization methodology of aniline, in the presence of g-C3N4. The as prepared Pani@g-C3N4 was characterized by scanning electron microscopy, transmission electron microscopy and X-ray diffraction (XRD). The morphological analysis showed well dispersed Pani in g-C3N4, as well as the coating of Pani on g-C3N4. The XRD further revealed this, and peaks of Pani as well as g-C3N4 was observed, thereby suggesting successful synthesis of the composite. The DC electrical conductivity studies under isothermal and cyclic aging conditions showed high stability of composites over 100 °C. Further, the synthesized composite material proved to be an excellent antimicrobial agent against both type i.e., gram positive Streptococcus pneumoniae and negative bacteria Escherichia coli. In the zone inhibition assay 18 ± 0.5, 16 ± 0.75 and 20 ± 0.5, 22 ± 0.5 mm zone diameter were found against E. coli and S. pneumoniae in presence of pure g-C3N4 and Pani@g-C3N4 at 50 µg concentrations, respectively. Further antimicrobial activity in the presence of sunlight in aqueous medium showed that Pani@g-C3N4 is more potent than pure g-C3N4. Full article
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