Journal Description
Complications
Complications
(ISSN 2813-4966) is an international, peer-reviewed, open access journal on the prevention, diagnosis, etiology, and management of complications in all aspects of basic, translational, and clinical research, as well as epidemiology. The journal seeks to offer best practices and expert experience, and recommendations on intra-operative and post-operative adverse events, published quarterly online by MDPI.
- Open Access— free for readers, with article processing charges (APC) paid by authors or their institutions.
- Rapid Publication: first decisions in 18 days; acceptance to publication in 4 days (median values for MDPI journals in the second half of 2024).
- Recognition of Reviewers: APC discount vouchers, optional signed peer review, and reviewer names published annually in the journal.
- Complications is a companion journal of JCM.
Latest Articles
Thirty-Day Complications Following Anterior Lumbar Interbody Fusion Versus Lumbar Disc Arthroplasty: A Propensity Score Matched Analysis
Complications 2025, 2(1), 2; https://doi.org/10.3390/complications2010002 - 9 Jan 2025
Abstract
The anterior lumbar interbody fusion (ALIF) and lumbar disc arthroplasty (LDA) procedures are both commonly performed to improve the quality of life and pain in people with lower back pain. However, few recent studies have compared 30-day complications on a large scale. The
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The anterior lumbar interbody fusion (ALIF) and lumbar disc arthroplasty (LDA) procedures are both commonly performed to improve the quality of life and pain in people with lower back pain. However, few recent studies have compared 30-day complications on a large scale. The objectives of this study were to compare the 30-day complications seen after ALIF and LDA and identify risk factors for these complications. The National Surgical Quality Improvement Program (NSQIP) database was queried between the years 2012–2021 (10 years in total) for records of patients who underwent either ALIF or LDA as a primary procedure. Patients in each group underwent a 1:1 propensity match for age, gender, BMI, ASA status, diabetes mellitus (DM), hypertension requiring medication, congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), inpatient/outpatient status, smoking status, and bleeding disorders. Bivariate and multivariate analyses were performed to determine significant differences in complications and risk factors between these cohorts. A total of 1218 propensity-matched subjects, with 609 receiving ALIF and 609 receiving LDA, were included in the analyses of this study. The incidence of extended length of stay (LOS) (>4 days) was higher in the ALIF cohort compared to the LDA cohort (14.6% vs. 4.76%, p < 0.001). Multivariate analysis demonstrated that subjects who underwent LDA had lower odds (Odds Ratio [OR]: 0.457; 95% Confidence Interval [CI]: 0.283–0.738, p = 0.001) of experiencing extended LOS compared to the ALIF cohort. Longer operative times increased the odds of prolonged LOS in both cohorts. The results of this study suggest that ALIF is associated with longer LOS than LDA when baseline demographic data are controlled. Further, longer operative times increase the odds that subjects receiving either ALIF or LDA will experience a prolonged LOS. Besides extended LOS, ALIF and LDA produce a relatively similar 30-day complication profile.
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Open AccessCase Report
Posterior Dislocation of Descemet Stripping Automated Endothelial Keratoplasty—A Case Report and Review
by
Valentino de Ruvo, Alfonso Strianese, Lily Chacra, Luca Rossetti, Fabio Patelli and Paolo Fogagnolo
Complications 2025, 2(1), 1; https://doi.org/10.3390/complications2010001 - 3 Jan 2025
Abstract
In this study, we describe a case of graft dislocation into the vitreous cavity after Descemet stripping automated endothelial keratoplasty (DSAEK), and review the risk factors and complications of posterior dislocation. A 70-year-old female with disruption of the iris–lens diaphragm experienced DSAEK graft
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In this study, we describe a case of graft dislocation into the vitreous cavity after Descemet stripping automated endothelial keratoplasty (DSAEK), and review the risk factors and complications of posterior dislocation. A 70-year-old female with disruption of the iris–lens diaphragm experienced DSAEK graft dislocation into the vitreous cavity during air re-bubbling at 1 week postoperatively. The corneal opacity hindered adequate visualization of the vitreous cavity for the immediate retrieval of the graft. Five days after re-bubbling, vitrectomy and corneal tissue removal was performed using a temporary Eckardt keratoprosthesis, and penetrating keratoplasty was subsequently performed. Two weeks after graft removal, a retinal detachment occurred. Silicon oil was used as a tamponade to reattach the retina. Three months after the last procedure, the retina was attached, and the cornea was clear. Posterior dislocation of DSAEK graft is a rare complication. A disrupted iris–lens diaphragm and previous vitrectomy are the main risk factors. Severe vision loss is more likely to occur when corneal tissue removal is delayed. In cases of delayed removal, it is advisable to take precautions to prevent possible retinal detachment.
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(This article belongs to the Special Issue Complications in Ophthalmology)
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Open AccessArticle
Treatment of Fractures of the Humeral Surgical Neck: MIROS Versus Intramedullary Nailing—A Retrospective Study
by
Michelangelo Palco, Gabriele Giuca, Domenico Fenga, Ilaria Sanzarello, Matteo Nanni and Danilo Leonetti
Complications 2024, 1(3), 83-90; https://doi.org/10.3390/complications1030013 - 18 Dec 2024
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This retrospective study compares the clinical outcomes of the Minimally Invasive Reduction and Osteosynthesis System (MIROS) and intramedullary nailing (IMN) in treating isolated surgical neck fractures of the humerus. A total of 42 patients were included, with 18 treated using MIROS and 24
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This retrospective study compares the clinical outcomes of the Minimally Invasive Reduction and Osteosynthesis System (MIROS) and intramedullary nailing (IMN) in treating isolated surgical neck fractures of the humerus. A total of 42 patients were included, with 18 treated using MIROS and 24 with IMN. The primary outcomes assessed were the complication rates, functional recovery (DASH score), pain levels (VAS), and radiological healing. The MIROS group exhibited a higher complication rate (22.2% vs. 8.8%), with K-wire migration and superficial infections being the most frequent. Patients treated with MIROS reported lower postoperative pain (VAS 45 ± 25.7) compared to the IMN group (VAS 58.1 ± 12.5). Both groups demonstrated radiological healing within three months, but one MIROS patient required reoperation due to hardware failure. No significant differences were observed in the DASH scores between the groups. Our findings suggest that IMN is a preferable treatment option for younger patients with good bone quality, while MIROS may still be beneficial for elderly patients with significant comorbidities, albeit with a higher risk of complications. Future prospective studies are recommended to confirm these findings.
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Open AccessCase Report
Management of Postoperative Left-Sided Chylothorax Using Indocyanine Green Fluorescence-Guided VATS
by
Luigi Lione, Alberto Busetto, Alessandro Bonis, Vincenzo Verzeletti, Eleonora Faccioli, Giovanni Comacchio, Giorgio Cannone, Michele Battistel, Alessandro Rebusso, Samuele Nicotra and Federico Rea
Complications 2024, 1(3), 79-82; https://doi.org/10.3390/complications1030012 - 29 Nov 2024
Abstract
Chylothorax is a rare complication occurring after cardio-thoracic surgical procedures. This condition presents challenges for diagnosis and treatment. Operative ductal ligation is the method of choice for relapsing or refractory cases, and it can be performed through the aid of IGC injection for
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Chylothorax is a rare complication occurring after cardio-thoracic surgical procedures. This condition presents challenges for diagnosis and treatment. Operative ductal ligation is the method of choice for relapsing or refractory cases, and it can be performed through the aid of IGC injection for the identification of chylous leakage. Our report presents the use of ICG fluorescence during VATS to successfully identify and treat a left-sided post-surgical chylothorax. The patient underwent a pulmonary wedge resection for a suspect malignant lesion and developed chylous leakage in the early postoperative period. On postoperative day 7, the patient underwent a revision thoracoscopy for hemostasis and thoracic duct ligation. ICG injections were performed through bilateral inguinal lymph nodes and approximately 15 min after we performed the re-thoracoscopy with effective identification and ligation of the chyle leakage. ICG fluorescence-guided VATS is a valuable and effective method for managing postoperative chylothorax, especially for left-sided leaks.
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(This article belongs to the Special Issue Preventing and Managing Surgical Complications: Perspectives from Surgeons)
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Open AccessSystematic Review
Pigtail Catheter Compared to Formal Intercostal Catheter for the Management of Isolated Traumatic Pneumothorax: A Systematic Review and Meta-Analysis
by
Khang Duy Ricky Le, Annie Jiao Wang, Karim Sadik, Kaylah Fink and Shasha Haycock
Complications 2024, 1(3), 68-78; https://doi.org/10.3390/complications1030011 - 8 Nov 2024
Abstract
(1) Background: The optimal management approach for adults with traumatic pneumothorax without haemothorax remains an area of debate. Specifically, there is lack of consensus as to whether insertion of a pigtail catheter is superior to a formal intercostal catheter in improving complication rates.
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(1) Background: The optimal management approach for adults with traumatic pneumothorax without haemothorax remains an area of debate. Specifically, there is lack of consensus as to whether insertion of a pigtail catheter is superior to a formal intercostal catheter in improving complication rates. (2) Methods: Medline, EMBASE, Cochrane Central, and the World Health Organisation International Clinical Trials Registry Platform databases were systematically searched for studies evaluating pigtail catheters compared to formal intercostal catheters for the management of traumatic pneumothorax. Investigative outcomes of interest included pain, duration management, failure, need for formal thoracoscopic surgery, need for supplemental oxygen, length of stay, infection and overall total complications. (3) Results: Three studies evaluating 280 patients were included in this analysis. There was no significant difference in total complications, rates of failure, length of stay or duration of management between pigtail catheters and formal intercostal catheters. This evidence was based on studies of low to moderate risk of bias with poor control for confounding factors. (4) Conclusions: This systematic review and meta-analysis demonstrates lack of evidence to suggest pigtail catheters are superior to formal intercostal catheter for traumatic pneumothorax. These findings may reflect a true absence of effect between either approach for this patient cohort or non-committal findings in light of limitations of the underlying evidence. Further prospective trials with larger sample sizes and control for confounders are required to validate the outcomes between these two modalities of treatment.
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(This article belongs to the Special Issue Preventing and Managing Surgical Complications: Perspectives from Surgeons)
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Open AccessCase Report
Successful Management of Gastric Leakage Post Gastric Sleeve by Gastric Bypass Conversion
by
Manuela Jaramillo Vásquez, Hernando Thorne Vélez, Isaac Mendoza Morales and Andrés Hanssen Londoño
Complications 2024, 1(3), 61-67; https://doi.org/10.3390/complications1030010 - 4 Nov 2024
Abstract
Gastric leak represents one of the most common, serious and challenging complications in bariatric procedures, and it is caused by both ischemic and mechanical failure. The management of these leaks remains controversial. In this clinical case, we describe the occurrence of a gastric
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Gastric leak represents one of the most common, serious and challenging complications in bariatric procedures, and it is caused by both ischemic and mechanical failure. The management of these leaks remains controversial. In this clinical case, we describe the occurrence of a gastric leak after a gastric sleeve, which was successfully treated by gastric bypass using a laparoscopic technique.
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(This article belongs to the Special Issue Preventing and Managing Surgical Complications: Perspectives from Surgeons)
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Open AccessReview
The Impact of Social Media on Public Perception and Litigation in Hernia Surgery Complications: A Narrative Review
by
René Gordon Holzheimer and Nadey Hakim
Complications 2024, 1(3), 51-60; https://doi.org/10.3390/complications1030009 - 8 Oct 2024
Abstract
Title: The Impact of Social Media on Public Perception and Litigation in Hernia Surgery Complications. Introduction: Social media significantly impacts public perception of healthcare, leading to increased litigation for complications after hernia surgery. Our research focused on terms like ‘inguinal hernia repair,’ ‘medico-legal,’
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Title: The Impact of Social Media on Public Perception and Litigation in Hernia Surgery Complications. Introduction: Social media significantly impacts public perception of healthcare, leading to increased litigation for complications after hernia surgery. Our research focused on terms like ‘inguinal hernia repair,’ ‘medico-legal,’ ‘informed consent,’ ‘litigation,’ ‘malpractice,’ ‘social media’, ‘mesh’, ‘Leistenbruch’, and OLG in Pubmed, Google Scholar, and Google. Results showed chronic postoperative pain as a common cause of malpractice claims, with ultrasound being a valuable diagnostic tool. Urological injuries account for a significant portion of complications after surgery. Mesh infection leads to hospital readmission, increased healthcare costs, and lawsuits. The quality of the consent process is crucial, and patient perceptions of mesh use influence their decision-making. Healthcare professionals must understand the impact of social media on public perception and provide comprehensive patient information for informed consent and satisfaction.
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Open AccessCase Report
When Nature Strikes Back: Understanding Intestinal Perforations Caused by Vegetable and Animal Bodies
by
Santiago Andrés Suárez-Gómez, Valentina Velasco-Muñoz and Fernando Escobar-Castañeda
Complications 2024, 1(3), 43-50; https://doi.org/10.3390/complications1030008 - 24 Sep 2024
Abstract
Foreign body intestinal perforation is a critical and potentially life-threatening condition that presents significant diagnostic challenges, especially in rural populations who are often distant from healthcare facilities and lack access to necessary resources. In these settings, the surgical approach is further complicated by
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Foreign body intestinal perforation is a critical and potentially life-threatening condition that presents significant diagnostic challenges, especially in rural populations who are often distant from healthcare facilities and lack access to necessary resources. In these settings, the surgical approach is further complicated by prolonged diagnostic times and delayed access to appropriate care. This article presents a series of cases involving patients with foreign body intestinal perforation of both vegetable and animal origin. Among these cases, one patient died due to delayed voluntary treatment, and another presented without leukocytosis, further complicating the diagnosis. Socioeconomic barriers made follow-up challenging in most cases, negatively impacting patient outcomes. This study details patient characteristics, surgical approaches, and outcomes. Community education, improved infrastructure, and greater awareness among healthcare providers are essential to improving outcomes, particularly in rural areas where healthcare delivery is more challenging and intensified efforts are required to enhance patient care and quality of life.
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(This article belongs to the Special Issue Preventing and Managing Surgical Complications: Perspectives from Surgeons)
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Open AccessCase Report
Staged Hybrid Treatment of Acute Type B Complicated Aortic and External Iliac Artery Dissection and Femoral Occlusion after Transcatheter Aortic Valve Implantation
by
Hernando Thorne-Vélez, Axel Tolstano Gleiser, Isaac Mendoza Morales, Ana Maria Thorne-Velez, Natalia Penaloza Barrios, Manuela Jaramillo Vasquez and William Daza Reatiga
Complications 2024, 1(2), 37-42; https://doi.org/10.3390/complications1020007 - 26 Aug 2024
Abstract
Percutaneous aortic valve replacement (TAVI) has become the treatment of choice for elderly patients with severe aortic valve stenosis because of its less invasive nature compared to surgery. As TAVI is increasingly offered, issues such as vascular lesions, access site problems, paravalvular leaks,
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Percutaneous aortic valve replacement (TAVI) has become the treatment of choice for elderly patients with severe aortic valve stenosis because of its less invasive nature compared to surgery. As TAVI is increasingly offered, issues such as vascular lesions, access site problems, paravalvular leaks, and aortic dissection (AD) are a few associated complications, needing consideration. AD after TAVI is rare but serious, occurring in 0.2% to 0.3% of cases, with both intraprocedural and late cases reported. This case study concerns a 68-year-old woman who developed Stanford B AD, external iliac artery dissection, and right common femoral artery occlusion after TAVI. Treatment included the stenting of the iliac and common femoral arteries, followed by a staged procedure: debranching, thoracic endovascular aortic repair (TEVAR), and endovascular aneurysm repair (EVAR), with satisfactory results. This case underscores the importance of vigilance in the management of TAVI-related complications to optimize patient care and outcomes.
Full article
(This article belongs to the Special Issue Preventing and Managing Surgical Complications: Perspectives from Surgeons)
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Open AccessCase Report
Postoperative Intestinal Intussusception in Polytraumatized Adult Patient: A Case Report
by
Claudia Viviana Jaimes González, María José Pereira Velásquez, Juan Pablo Unigarro Villota and Adriana Patricia Mora Lozada
Complications 2024, 1(2), 32-36; https://doi.org/10.3390/complications1020006 - 17 Jul 2024
Abstract
Background: Intestinal intussusception is defined as the invagination of one segment of the intestine into the lumen of an adjacent intestinal segment, resulting in the mechanical intestinal obstruction of multifactorial origin with a high risk of morbidity and mortality. It is a rare
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Background: Intestinal intussusception is defined as the invagination of one segment of the intestine into the lumen of an adjacent intestinal segment, resulting in the mechanical intestinal obstruction of multifactorial origin with a high risk of morbidity and mortality. It is a rare pathology in adults with a nonspecific clinical presentation. We present the case of a 26-year-old male patient who was admitted postoperatively after multiple extra institutional surgical interventions due to polytrauma secondary to a work-related accident that caused high-impact trauma by a solids mixer. However, he was referred to our institution due to suspected vascular trauma in the right femoral artery. During his hospital stay, he developed intolerance to oral intake associated with pain, abdominal distension, and persistent emetic episodes despite medical management. Consequently, an abdominal CT scan with double contrast was requested, revealing intestinal intussusception secondary to intestinal adhesions, which required new surgical management with a favorable resolution; Discussion: Intussusception in the adult population is rare and is primarily caused by an identifiable structural lesion. It is one of the most challenging pathologies in terms of diagnosis and management due to its nonspecific presentation. However, when postoperative symptoms indicating intestinal obstruction appear, a computed tomography scan is considered the imaging modality of choice for diagnosing intussusception in adults; Conclusions: The development of postoperative peritoneal adhesions is a common cause of intestinal obstruction that can lead to complications such as intestinal intussusception, requiring additional interventions. Therefore, it is vital to identify their presence to reduce morbidity and mortality.
Full article
(This article belongs to the Special Issue Preventing and Managing Surgical Complications: Perspectives from Surgeons)
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Open AccessCase Report
Aortic Endograft Infections: A Race against Time
by
Santiago Andrés Suárez-Gómez, Esteban Portilla-Rojas, María Fernanda Rodríguez, Natalia Velásquez-Solarte, Sara Restrepo, Luis Felipe Cabrera-Vargas, Nicolas Forero and Marcos Tarazona
Complications 2024, 1(1), 24-31; https://doi.org/10.3390/complications1010005 - 21 Jun 2024
Abstract
Abdominal aortic aneurysms (AAAs) are a highly asymptomatic vascular pathology with an increasing risk of rupture, leading to high mortality. Upon detection, treatment primarily involves lifestyle changes to slow the growth rate. Aneurysm rupture requires immediate surgical intervention due to its high mortality.
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Abdominal aortic aneurysms (AAAs) are a highly asymptomatic vascular pathology with an increasing risk of rupture, leading to high mortality. Upon detection, treatment primarily involves lifestyle changes to slow the growth rate. Aneurysm rupture requires immediate surgical intervention due to its high mortality. Endovascular aneurysm repair (EVAR) is a common treatment option, involving stent placement at the aneurysm site. However, the stent is a foreign body; therefore, it is susceptible to immune response and infection. This case series presents patients with infected endovascular stents following a diagnosis of abdominal infrarenal aortic aneurysm and EVAR. The patients’ follow-ups revealed varying prognoses, complications, and treatments post-infection. These findings are compared with outcomes reported in the medical literature. Preventing aortic stent graft infection through proper aseptic techniques is crucial. This practice reduces patient complications, shortens inpatient hospice stays, and, most importantly, enhances patient quality of life.
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(This article belongs to the Special Issue Preventing and Managing Surgical Complications: Perspectives from Surgeons)
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Open AccessArticle
Efficiency of Orthopaedic Audits in a Level-1 Trauma Centre Using a Modified Clavien–Dindo Complications Classification
by
Adrian J. Talia, Nicholas Furness and Susan M. Liew
Complications 2024, 1(1), 14-23; https://doi.org/10.3390/complications1010004 - 12 Jun 2024
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Background: Complications are an inevitable part of orthopaedic surgery, and how one defines complications can have an impact on the ability to learn from them. There have been issues with a commonly used classification system first outlined by Clavien and Dindo. Our aim
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Background: Complications are an inevitable part of orthopaedic surgery, and how one defines complications can have an impact on the ability to learn from them. There have been issues with a commonly used classification system first outlined by Clavien and Dindo. Our aim was to evaluate a modification of this classification system developed for use in our department, with our hypothesis being that this could make our audit presentations more efficient. Methods: A modified Clavien–Dindo Classification was prospectively applied to all complications recorded in the orthopaedic departmental audits at our institution for a 12-month period. The audit discussion was recorded and analysed and compared with the complication audits for the preceding 12-month period. Results: We analysed eight audit presentations before and eight audit presentations after the introduction of a modified Clavien–Dindo classification to our orthopaedic complications over a 2-year period. The number of PowerPoint™ slides (103 vs. 84, p = 0.03) and the time spent on each presentation (88 vs. 71 min, p = 0.02) decreased significantly with the introduction of the modified classification. The novel system was found to have high inter-observer reliability. Conclusions: The modified Clavien–Dindo classification system is a reproducible classification system for orthopaedic complications. It made our audit presentations more efficient.
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Open AccessEditorial
Complications in Vascular and Endovascular Surgery: To Defeat Your Enemy, You Must Know Your Enemy
by
Mario D’Oria
Complications 2024, 1(1), 11-13; https://doi.org/10.3390/complications1010003 - 21 Mar 2024
Abstract
In recent decades, the field of vascular surgery has been revolutionized by the introduction and ever-rising growth of endovascular techniques for almost all arterial and venous diseases, mainly owing to their reduced morbidity and mortality rates as compared with conventional open surgical approaches
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In recent decades, the field of vascular surgery has been revolutionized by the introduction and ever-rising growth of endovascular techniques for almost all arterial and venous diseases, mainly owing to their reduced morbidity and mortality rates as compared with conventional open surgical approaches [...]
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Open AccessProtocol
Systematic Review and Meta-Analysis Assessing Perioperative and Oncologic Outcomes in Patients Undergoing Urologic Procedures with a History of Prior Abdominal/Pelvic Surgery: Study Protocol
by
Michael B. Eppler, Aref S. Sayegh, Ryan Davis, Sij Hemal, Mihir Desai, Rene Sotelo, Inderbir Gill and Giovanni E. Cacciamani
Complications 2024, 1(1), 6-10; https://doi.org/10.3390/complications1010002 - 18 May 2023
Abstract
Prior abdominal/pelvic surgery (PAS) has the potential to impact perioperative and oncologic outcomes in patients undergoing urologic surgery. There is a need to study outcomes in this population to determine if reoperation is safe and feasible. This review will follow the Preferred Reporting
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Prior abdominal/pelvic surgery (PAS) has the potential to impact perioperative and oncologic outcomes in patients undergoing urologic surgery. There is a need to study outcomes in this population to determine if reoperation is safe and feasible. This review will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and has been registered with PROSPERO (ID: CRD42022361935). The search for articles will be conducted in PubMed, Scopus, and Web of Science, and additional articles may be identified by reviewing the manuscripts of the included literature. Outcomes of interest will be used to determine if reoperation is safe and feasible in this population.
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Open AccessEditorial
Complications—A New Open-Access Journal for Improving Our Understanding of Prevention and Management of Surgical, Interventional and Anesthesiologic Complications and Adverse Events
by
Giovanni E. Cacciamani
Complications 2024, 1(1), 1-5; https://doi.org/10.3390/complications1010001 - 31 Dec 2022
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The reporting of surgical, interventional, and anesthesiologic complications is essential for improving the quality of healthcare delivery and for standardizing and reproducing outcomes data. To address underlying issues in the reporting of complications and adverse events, it may be necessary to provide education
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The reporting of surgical, interventional, and anesthesiologic complications is essential for improving the quality of healthcare delivery and for standardizing and reproducing outcomes data. To address underlying issues in the reporting of complications and adverse events, it may be necessary to provide education and training, establish standardized definitions and reporting requirements, and create incentives for healthcare providers to report complications. Complications, a new international peer-reviewed open access journal, aims to provide best practice and expert opinion recommendations on the prevention, diagnosis, pathogenesis, and management of complications in basic, translational, and clinical research, as well as epidemiology. The journal invites authors to address four components of perioperative adverse events: assessment, reporting, analysis of anticipatable factors, and management. The usability and practical implications of this information can have significant implications for academic and clinical practice. The prioritization of the assessment and reporting of adverse events to standardize their management and improve the understanding of the impact of these events on patients’ peri-operative course.
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Special Issue in
Complications
Preventing and Managing Surgical Complications: Perspectives from Surgeons
Guest Editor: Luis Felipe Cabrera-VargasDeadline: 30 April 2025
Special Issue in
Complications
Complications in Ophthalmology
Guest Editors: Paolo Fogagnolo, Diego Strianese, Antonio FerrerasDeadline: 15 June 2025