Dermatopathology and the Diagnosis of Skin Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 702

Special Issue Editor


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Guest Editor
Department of Dermatology, Medical University of Warsaw, Warsaw, Poland
Interests: dermatology; dermatopathology; diagnosis; alopecia

Special Issue Information

Dear Colleagues,

Dermatopathology is fundamental to accurate diagnosis in dermatology, as it offers a definitive understanding of the underlying pathological processes that manifest as skin lesions. With the increasing incidence of skin cancers and the complexity of inflammatory and autoimmune skin disorders, the role of dermatopathologists has become even more crucial.

This Special Issue recognizes the importance of staying abreast with the latest research, techniques, and diagnostic tools that are shaping the future of dermatopathology. Some of the highlighted topics include, but are not limited to, the following:

  • Advances in immunohistochemistry and molecular diagnostics;
  • Updates in skin cancer diagnosis;
  • Inflammatory and autoimmune skin diseases;
  • Challenging cases in dermatopathology;
  • Teledermatopathology and digital pathology.

We look forward to receiving your contributions.

Dr. Joanna Czuwara
Guest Editor

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Keywords

  • dermatopathology
  • skin diseases
  • histopathology
  • immunohistochemistry
  • molecular diagnostics
  • biomarkers

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Published Papers (1 paper)

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8 pages, 2248 KiB  
Case Report
Diagnostic Difficulties of Erosive Lichen Planus in a Pediatric Patient
by Carolyn Szwed, Olivia Gudziewski, Marta Sar-Pomian, Malgorzata Olszewska, Lidia Rudnicka and Joanna Czuwara
Diagnostics 2025, 15(1), 35; https://doi.org/10.3390/diagnostics15010035 - 27 Dec 2024
Viewed by 501
Abstract
Background: Lichen planus (LP) is a chronic inflammatory disease that can present with significant morbidity, particularly in children. Erosive lichen planus (ELP), its rare destructive subtype, can be particularly difficult to diagnose and manage. We present a rare pediatric case of ELP with [...] Read more.
Background: Lichen planus (LP) is a chronic inflammatory disease that can present with significant morbidity, particularly in children. Erosive lichen planus (ELP), its rare destructive subtype, can be particularly difficult to diagnose and manage. We present a rare pediatric case of ELP with multisite involvement and discuss the differential diagnosis. Case Presentation: A 12-year-old boy presented with painful erosions and ulcers on the lateral tongue and dystrophic nails. His six-year history of tongue and nail lesions prompted several comprehensive examinations. Laboratory tests did not reveal any abnormalities. Histopathological examination of the tongue lesions was representative of ELP. Line-field confocal optical coherence tomography (LC-OCT) examination of the tongue lesions showed features that strongly correlated with histopathology. The patient was later hospitalized due to dysphagia and esophageal food impaction, during which esophageal ELP was confirmed. The patient was initially managed with topical corticosteroids. He was later started on systemic therapy in the form of methotrexate and low-dose naltrexone to address his symptoms and disease presentation. Conclusions: This case highlights the complexities of diagnosis and management of ELP in pediatric patients. A multidisciplinary approach and regular follow-up are necessary to manage symptoms, prevent complications, and improve quality of life. Full article
(This article belongs to the Special Issue Dermatopathology and the Diagnosis of Skin Diseases)
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