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Diagnostics
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Meningioma: Radiomics, Diagnosis and Management
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Meningioma: Radiomics, Diagnosis and Management

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 705

Special Issue Editor

Prof. Dr. Manoj Mannil

E-Mail Website
Guest Editor
1. Department of Radiology, University Hospital Muenster, DE-48149 Muenster, Germany
2. Institute for Diagnostic and Interventional Radiology, Caritas-Hospital, DE-97980 Bad Mergentheim, Germany
Interests: radiomics; machine learning; meningioma

Special Issue Information

Dear Colleagues,

This Special Issue delves into the multifaceted landscape of meningiomas, providing a comprehensive exploration of radiomics, diagnostics and treatment strategies. Meningiomas, though generally benign, present complex challenges due to their diverse manifestations and potential for neurological impact. This issue amalgamates cutting-edge research, encompassing the evolution of radiomics in meningioma diagnosis and prognosis prediction, leveraging advanced imaging techniques for enhanced precision.

Contributions within this issue elucidate diagnostic intricacies, emphasizing the pivotal role of radiomics in characterizing meningiomas with precision and accuracy. Experts from diverse disciplines, including neurosurgery, radiology, oncology and pathology, converge within this issue, fostering interdisciplinary insights critical for a holistic understanding of meningioma management. Ultimately, this Special Issue serves as a cornerstone, propelling the field forward by synthesizing contemporary research, fostering dialogue and paving the way for further advancements in the diagnosis and management of meningiomas.

Prof. Dr. Manoj Mannil
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • meningioma
  • radiomics
  • diagnosis
  • management
  • neurosurgery

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Published Papers (1 paper)

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12 pages, 11436 KiB  
Case Report
The Management of a Giant Convexity en Plaque Anaplastic Meningioma with Gerstmann Syndrome: A Case Report of Surgical Outcomes in a 76-Year-Old Male
by Corneliu Toader, Felix Mircea Brehar, Mugurel Petrinel Radoi, Matei Serban, Razvan-Adrian Covache-Busuioc, Ghaith S. Aljboor and Radu M. Gorgan
Diagnostics 2024, 14(22), 2566; https://doi.org/10.3390/diagnostics14222566 - 15 Nov 2024
Viewed by 350
Abstract
Background: This case report highlights a rare presentation of a giant convexity en plaque anaplastic meningioma, located in the left frontoparietal parasagittal region, infiltrating the superior sagittal sinus, and associated with Gerstmann syndrome. This study aims to explore the clinical challenges, surgical management, [...] Read more.
Background: This case report highlights a rare presentation of a giant convexity en plaque anaplastic meningioma, located in the left frontoparietal parasagittal region, infiltrating the superior sagittal sinus, and associated with Gerstmann syndrome. This study aims to explore the clinical challenges, surgical management, and potential reversibility of neurological deficits induced by the tumor, including those characteristic of Gerstmann syndrome. Methods: A 76-year-old male patient presented with a history of worsening expressive aphasia and cognitive impairments, culminating in a generalized seizure. Preoperative imaging confirmed a 4 × 6 cm highly vascularized tumor with significant peritumoral edema. The patient underwent near-total resection of the tumor, aiming for a Simpson grade 2 resection, while managing hypervascularity and brain edema. Histological analysis confirmed the diagnosis of anaplastic meningioma (WHO Grade III), showing features such as necrosis, brain invasion, and high mitotic activity. Results: Post-surgical follow-up demonstrated significant improvement in the patient’s neurological deficits, particularly in expressive language and cognitive function, suggesting a potential reversal of Gerstmann syndrome. Postoperative imaging revealed a moderate degree of cerebral collapse and absence of contrast leakage. Two-month follow-up confirmed no recurrence of neurological deficits. Conclusions: This case emphasizes the complexity of managing giant convexity en plaque anaplastic meningiomas, particularly when associated with Gerstmann syndrome. Surgical resection, despite the challenges posed by tumor size, hypervascularity, and peritumoral edema, can lead to significant neurological recovery, highlighting the potential reversibility of tumor-induced Gerstmann syndrome. Full article
(This article belongs to the Special Issue Meningioma: Radiomics, Diagnosis and Management)
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