Diagnosis of Biliary-Pancreatic Disorders: Challenges and Progress

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (20 April 2023) | Viewed by 8082

Special Issue Editor


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Guest Editor
Department of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan
Interests: biliary tract diseases; pancreatic diseases; EUS

Special Issue Information

Dear Colleagues, 

In recent years, we have witnessed remarkable progress in the diagnosis of biliary-pancreatic disorders thanks to advances in endoscopic procedures and image diagnosis (e.g., CT, MRI, EUS, ERCP, cholangioscopy, and pancreatoscopy). The diagnosis of early biliary-pancreatic cancer is obviously an important issue, and the aforementioned techniques can increase the chances of early biliary-pancreatic cancer detection; however, there are still significant gaps in our knowledge as regards the follow-up period and key findings. Advances in endoscopic devices including the EUS-FNA needle can improve the accuracy of malignant disease diagnosis and help us to obtain large tissue samples for next-generation sequencing. Tissue sampling under ERCP is not sufficient; however, new devices and methods can improve the diagnostic accuracy of histological and cytological diagnosis. The detection of the spread of malignant disease is also important in determining treatment. For benign diseases, differential diagnosis for the biliary and pancreatic duct stricture is important, while tissue sampling for benign diseases, including IgG4-related disease, is required for treatment decisions.

In this issue, we welcome manuscripts describing novel data, methods, devices, and reviews related to the topic of “Advances in the Diagnosis of Biliary-Pancreatic Disorders”.

Dr. Mitsuru Okuno
Guest Editor

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Keywords

  • biliary-pancreatic cancer
  • malignancy
  • benign biliary
  • stricture
  • ERCP
  • EUS
  • EUS-FNA
  • IgG4-related disease

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Published Papers (1 paper)

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11 pages, 2197 KiB  
Case Report
The Curious Case of the Choledochal Cyst—Revisiting the Todani Classification: Case Report and Review of the Literature
by Adrian Miron, Liliana Gabriela Popa, Elena Adelina Toma, Valentin Calu, Radu Florin Parvuletu and Octavian Enciu
Diagnostics 2023, 13(6), 1059; https://doi.org/10.3390/diagnostics13061059 - 10 Mar 2023
Cited by 3 | Viewed by 7795
Abstract
Choledochal cysts (CCs) are rare occurrences presenting as dilatations of biliary structures, which can present as single or multiple dilatations and can appear as both intra- and extrahepatic anomalies. The most widespread classification of CCs is the Todani classification, but there have been [...] Read more.
Choledochal cysts (CCs) are rare occurrences presenting as dilatations of biliary structures, which can present as single or multiple dilatations and can appear as both intra- and extrahepatic anomalies. The most widespread classification of CCs is the Todani classification, but there have been numerous reports of cysts that do not fall into any of the types described. We present such a case—a male patient 36 years of age who underwent preoperative CT, MRCP, and ERCP, which mistakenly indicated a type II Todani CC, and intraoperatively was found to be located at the confluence of the hepatic ducts and encompassed the origin of the common bile duct. Complete resection of the cyst and the proximal segment of the common bile duct was performed, and reconstruction was carried out by Roux-en-Y double-tutorized hepaticojejunostomy. Considering the risk of malignant transformation, the frequent preoperative misdiagnosis, as well as the technically challenging surgery required in such cases, we advocate for a revision of the classification and raise awareness of the need for guidelines regarding the proper short-term and long-term management of this disease to ensure adequate quality of life and disease-free survival for patients. Full article
(This article belongs to the Special Issue Diagnosis of Biliary-Pancreatic Disorders: Challenges and Progress)
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