Advances in the Diagnosis of Skin Disease

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 2962

Special Issue Editor

Special Issue Information

Dear Colleagues,

Many types of diagnostic tools have been, and are expected to be throughout the year, developed for the diagnosis, prognosis, and therapy of skin diseases. In this Special Issue (SI), we aim to analyze the different possibilities of diagnosing neoplastic, inflammatory, and infectious diseases, spanning from clinical pictures to histopathological features, with great attention being paid to artificial intelligence (AI) and algorithms.

Dr. Gerardo Cazzato
Guest Editor

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Keywords

  • dermatology
  • dermatopathology
  • skin diseases
  • neoplastic diseases
  • inflammatory dermatopathology
  • CTCL
  • melanoma
  • squamous cell carcinoma
  • basal cell carcinoma
  • infectious diseases

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Published Papers (2 papers)

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Research

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9 pages, 222 KiB  
Article
The Impact of the COVID-19 Pandemic on Melanoma Diagnosis: A Single-Center Study
by Adrian-Horațiu Sabău, Iuliu-Gabriel Cocuz, Raluca Niculescu, Andreea Cătălina Tinca, Andreea Raluca Szoke, Bianca-Andreea Lazar, Diana Maria Chiorean and Ovidiu Simion Cotoi
Diagnostics 2024, 14(18), 2032; https://doi.org/10.3390/diagnostics14182032 - 13 Sep 2024
Viewed by 598
Abstract
(1) Background: Melanoma represents the most aggressive form of skin cancer, with an increasing incidence and numerous risk factors. The COVID-19 pandemic has led to modifications in work protocols. This study aims to elucidate potential changes in the number and characteristics of primary [...] Read more.
(1) Background: Melanoma represents the most aggressive form of skin cancer, with an increasing incidence and numerous risk factors. The COVID-19 pandemic has led to modifications in work protocols. This study aims to elucidate potential changes in the number and characteristics of primary melanomas diagnosed in the Pathology Department of the Târgu Mureș County Clinical Hospital before, during, and after the COVID-19 pandemic. (2) Methods: This study included 140 patients grouped into six periods: two pre-COVID-19 periods, the COVID-19 pandemic period, and three post-COVID-19 periods. Epidemiological data, diagnoses, and histopathological reports were analyzed. (3) Results: The number of cases diagnosed during the COVID-19 pandemic was significantly lower than in the other analyzed periods. Regarding the monitored parameters, a statistically significant increase was observed in the first two post-COVID-19 periods, with a return to values similar to those of the first period in the last analyzed period. Additionally, a statistically significant increase in the incidence of distant metastases was identified in the post-COVID-19 periods. (4) Conclusions: The COVID-19 pandemic had a negative impact on the diagnosis of new melanoma cases, leading to an increase in the number of cases and a worsening of prognostic parameters. Full article
(This article belongs to the Special Issue Advances in the Diagnosis of Skin Disease)

Review

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12 pages, 4276 KiB  
Review
Tumid Lupus Erythematosus (TLE): A Review of a Rare Variant of Chronic Cutaneous Lupus Erythematosus (cCLE) with Emphasis on Differential Diagnosis
by Maged Daruish, Francesca Ambrogio, Caterina Foti, Alessandra Filosa and Gerardo Cazzato
Diagnostics 2024, 14(7), 780; https://doi.org/10.3390/diagnostics14070780 - 8 Apr 2024
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Abstract
Tumid lupus erythematosus (TLE) has been the subject of heated debate regarding its correct nosographic classification. The definition of TLE has changed over time, varying according to the different studies performed. In this review, we address the initial definition of TLE, the changes [...] Read more.
Tumid lupus erythematosus (TLE) has been the subject of heated debate regarding its correct nosographic classification. The definition of TLE has changed over time, varying according to the different studies performed. In this review, we address the initial definition of TLE, the changes that have taken place in the understanding of TLE, and its placement within the classification of cutaneous lupus erythematosus (CLE), with a focus on clinical, histopathological, immunophenotypical, and differential diagnosis aspects. Full article
(This article belongs to the Special Issue Advances in the Diagnosis of Skin Disease)
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