Emerging Role of Ultrasound Imaging in the Diagnosis and Management of Skin Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 3207

Special Issue Editor


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Guest Editor
1. Department of Medical Ultrasound, Shanghai Tenth People’s Hospital, Shanghai 200072, China
2. Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment, Shanghai 200072, China
Interests: ultrasound diagnosis; AI; telemedicine

Special Issue Information

Dear Colleagues,

In recent years, ultrasound imaging technology has been widely used and has played an increasingly important role in diagnosing and treating skin diseases, providing a large amount of key visual information in order to meet the challenges of complex skin diseases. Skin ultrasound imaging is a new technology category that is clinically widely endorsed. In this context, the large-scale application of ultrasound in skin diseases has gradually gained attention. In this regard, we would like to set up a new Special Issue on applying ultrasound imaging technology in skin diseases and focus on publishing some of the latest, high-quality, and excellent clinical research.

Dr. Lehang Guo
Guest Editor

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Published Papers (3 papers)

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Research

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11 pages, 2876 KiB  
Article
Dermoscopy, Line-Field Confocal Optical Coherence Tomography, Reflectance Confocal Microscopy, and Ultra-High-Frequency Ultrasound: Clues for the Diagnosis of Hidrocystomas
by Maria Erasti, Martina D’Onghia, Anastasia Batsikosta, Mariano Suppa, Linda Tognetti, Simone Cappilli, Ketty Peris, Francesca La Marca, Jean Luc Perrot, Giovanni Rubegni, Pietro Rubegni and Elisa Cinotti
Diagnostics 2024, 14(23), 2671; https://doi.org/10.3390/diagnostics14232671 - 27 Nov 2024
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Abstract
Background/Objectives: Hidrocystomas, eccrine and apocrine, are rare cystic lesions that form benign tumors of the sweat glands. This study aimed to describe the clinical features of hidrocystomas and evaluate the role of non-invasive imaging techniques, including dermoscopy, Line-field Confocal Optical Coherence Tomography (LC-OCT), [...] Read more.
Background/Objectives: Hidrocystomas, eccrine and apocrine, are rare cystic lesions that form benign tumors of the sweat glands. This study aimed to describe the clinical features of hidrocystomas and evaluate the role of non-invasive imaging techniques, including dermoscopy, Line-field Confocal Optical Coherence Tomography (LC-OCT), Reflectance Confocal Microscopy (RCM), and Ultra-High-Frequency Ultrasound (UHFUS), in their diagnosis. Methods: In total, seven cases of hidrocystomas were collected from the Dermatologic Clinic of the University of Siena, Italy. Predefined dermoscopic, LC-OCT, RCM, and UHFUS features were retrospectively described. Results: Overall, hidrocystomas were located on the face, mainly presenting as blue/purple-bluish translucent papules (71%). Dermoscopic examination revealed a homogeneous purple-bluish color (71%), white pale halo (71%), and shiny globules at the periphery (57%). LC-OCT identified a hyporeflective cupoliform round structure in the dermis with a bright and thick contour, while UHFUS showed a round structure in the dermis filled with hypoechoic content. Conclusions: Non-invasive imaging techniques could significantly enhance the diagnostic accuracy of hidrocystomas, aid in differentiation from other lesions, and minimize unnecessary biopsies. Full article
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15 pages, 1891 KiB  
Article
Novel Strategy in the Detection of Adverse Cutaneous Drug Reactions: A Case Series Study
by Erika-Gyöngyi Bán, Patrick Lechsner, Eszter-Anna Dho-Nagy, Maria-Antonia Balan, István Major-Szakács, Attila Brassai, Zsuzsánna Simon-Szabó and Corina Ureche
Diagnostics 2024, 14(6), 575; https://doi.org/10.3390/diagnostics14060575 - 7 Mar 2024
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Abstract
With multimorbidity on the rise, adverse cutaneous drug reactions are becoming a daily challenge in clinical practice. The objective evaluation of the skin lesion is crucial but hardly realized due to missing technology and guidelines. In this study, the novel Dermus SkinScanner-U, an [...] Read more.
With multimorbidity on the rise, adverse cutaneous drug reactions are becoming a daily challenge in clinical practice. The objective evaluation of the skin lesion is crucial but hardly realized due to missing technology and guidelines. In this study, the novel Dermus SkinScanner-U, an optically guided high-frequency ultrasound imaging device, was evaluated regarding its comparability with the Dermatology Life Quality Index (DLQI) and the pharmacological analysis of the patients’ drug therapy. A total of 40 adult patients were evaluated, all with chronic medication use and skin lesions that led to non-compliance toward the pharmacotherapy. With the ongoing aim of further improving the methodology, the first results, with two detailed patient cases, are presented here. It was concluded that in the cases evaluated, there was a significant correlation between the characteristics of the lesions observed on the optical and ultrasound image, the DLQI score, and the pharmacological analysis. The next steps include increasing the scale of the study to ultimately develop a quality-assured methodology for the correct diagnosis of skin-related adverse drug reactions and to prepare a database with the most frequently observed events. Full article
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Review

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14 pages, 1303 KiB  
Review
High-Frequency Ultrasonography in Hair and Nail Disorders—How It May Be Helpful
by Adriana Polańska, Dominik Mikiel, Marta Szymoniak-Lipska, Barbara Olszewska and Aleksandra Dańczak-Pazdrowska
Diagnostics 2025, 15(3), 332; https://doi.org/10.3390/diagnostics15030332 - 30 Jan 2025
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Abstract
Ultrasonography is a recognized method of tissue visualization in medicine, which is based on the use of mechanical waves (ultrasound). Its application in dermatology requires the use of higher frequencies, hence the use of high-frequency ultrasonography (HFUS) is recommended. HFUS has gained approval [...] Read more.
Ultrasonography is a recognized method of tissue visualization in medicine, which is based on the use of mechanical waves (ultrasound). Its application in dermatology requires the use of higher frequencies, hence the use of high-frequency ultrasonography (HFUS) is recommended. HFUS has gained approval in many areas of dermatology, including imaging of skin appendages [nail unit (NU) and hair follicles]. The analysis of the changing echogenicity of structures under the influence of inflammatory and neoplastic processes is used to assess the extent of the disease, treatment planning as well as in monitoring therapeutic effects. The aim of our work is to present the possibilities of visualizing NUs and scalps with the use of HFUS. Full article
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