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Diagnostics
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New Frontiers in Diagnostics for Cataract Surgery
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New Frontiers in Diagnostics for Cataract Surgery

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 12653

Special Issue Editors

Prof. Dr. Robert Rejdak

E-Mail Website
Guest Editor
Department of General Ophthalmology and Pediatric Ophthalmology Service, Medical University of Lublin, Lublin, Poland
Interests: retinal pharmacology; retinal neuroprotection; retinal neurodegeneration; latest techniques in ocular imaging; treatment of eye injuries; treatment of rare eye diseases
Special Issues, Collections and Topics in MDPI journals
Dr. Mario Damiano Toro

E-Mail Website
Guest Editor
Department of General Ophthalmology, Medical University of Lublin, 20-079 Lublin, Poland
Interests: cataract surgery; ocular trauma managment; vitreoretinal surgery; experimental ocular surgery; 3D surgery; secondary IOL implantation; pole-to-pole surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cataract surgery is the most common surgical procedure performed in developed countries. Recently, new technologies have dramatically turned its approach upside down, providing a way for a safer and more effective surgical treatment, especially in complex cases and in the treatment of surgical-related complications. The aim of this Special Issue is to provide an overview on new diagnostics tools in cataract surgery together to the best evidence for proper perioperative and postoperative assessments.

We emphasize new diagnostics for cataract treatment and the best strategies for the prevention of its complications. We strive to create a holistic concept throughout the process of diagnosis and treatment based on an individualized and a standardized view, so that cataract treatment will hopefully not be a challenge in the future.

Prof. Robert Rejdak
Dr. Mario Damiano Toro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Cataract surgery diagnostics
  • Secondary IOL implantation
  • Combined surgery
  • Risk factors assessment
  • Complications’ management
  • Preoperative diagnostic assessment
  • Femto-cataract
  • Posterior capsule rupture management
  • 3D surgery
  • Antibiotic prophylaxis
  • Complex cases’ management
  • Post-operative follow-up
  • Biometry
  • Topography
  • Endothelial cell count
  • Ocular surface diagnostics

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Published Papers (4 papers)

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Research

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11 pages, 2611 KiB  
Article
Simultaneously Monitoring Whole Corneal Injury with Corneal Optical Density and Thickness in Patients Undergoing Cataract Surgery
by Tzu-Han Hsieh, Hun-Ju Yu, I-Hui Yang, Ren-Wen Ho, Yu-Ting Hsiao, Po-Chiung Fang and Ming-Tse Kuo
Diagnostics 2021, 11(9), 1639; https://doi.org/10.3390/diagnostics11091639 - 7 Sep 2021
Cited by 7 | Viewed by 1859
Abstract
To pursue the least corneal implication during cataract surgery, this study aimed to monitor corneal wound injury after cataract surgery with a novel method. The prospective cohort study involved thirty-two patients, who were assessed by a Scheimpflug tomography AxL® (Oculus GmbH, Wetzlar, [...] Read more.
To pursue the least corneal implication during cataract surgery, this study aimed to monitor corneal wound injury after cataract surgery with a novel method. The prospective cohort study involved thirty-two patients, who were assessed by a Scheimpflug tomography AxL® (Oculus GmbH, Wetzlar, Germany) via the following two kinds of indices: whole corneal optical density (COD) and corneal thickness (CT), two weeks before and one month after cataract surgery. The results of the COD revealed that corneal annuli 0.0–2.0 mm and 2.0–6.0 mm, and the average and maximal values at the incisional site significantly increased postoperatively. Also, the anterior and central stroma of 0.0–2.0 mm, and all three depths of 2.0–6.0 mm, increased remarkably after the operation. For the CT, all ranges of diameters plus incisional sites showed significant increases postoperatively. Furthermore, we analyzed the differences (delta) of COD and CT between pre- and post-operation, and found significant correlations between the delta of COD and the delta of CT, regarding annuli 0.0–2.0 mm, 2.0–6.0 mm, and 6.0–10.0 mm, but no correlation at the incisional site, with either average density or maximal density, was detected. We concluded that whole COD and CT, especially at the central zones of the cornea (annulus < 6 mm), are both valuable parameters in the assessment of corneal damage post-cataract surgery, and are independent indices at the incisional site. Full article
(This article belongs to the Special Issue New Frontiers in Diagnostics for Cataract Surgery)
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18 pages, 1090 KiB  
Article
Corneal Analysis with Swept Source Optical Coherence Tomography in Patients with Coexisting Cataract and Fuchs Endothelial Corneal Dystrophy
by Anna Nowińska, Edyta Chlasta-Twardzik, Michał Dembski, Klaudia Ulfik-Dembska and Edward Wylęgała
Diagnostics 2021, 11(2), 223; https://doi.org/10.3390/diagnostics11020223 - 2 Feb 2021
Cited by 5 | Viewed by 2666
Abstract
This study focused on defining the characteristic features of keratometry and pachymetry elevation maps based on swept source optical coherence tomography (SS OCT) in Fuchs endothelial corneal dystrophy (FECD) eyes with a coexisting cataract. 70 eyes of 35 patients diagnosed with FECD and [...] Read more.
This study focused on defining the characteristic features of keratometry and pachymetry elevation maps based on swept source optical coherence tomography (SS OCT) in Fuchs endothelial corneal dystrophy (FECD) eyes with a coexisting cataract. 70 eyes of 35 patients diagnosed with FECD and a coexisting cataract and 70 control eyes were included in this prospective, controlled, observational, cross-sectional study. Features characteristic of intermediately affected eyes included an increased corneal thinnest thickness (CTT) (p = 0.01), 3 and 6 mm asymmetry (p < 0.0001), higher order Fourier indices (p < 0.05 and p ≤ 0.0001, respectively), chord µ, and a posterior Ectasia Screening Index (pESI) (p < 0.01). The lack of agreement between the anterior and posterior elevation map and a significant area of negative values in the posterior map were detected. In advanced FECD eyes, our study additionally revealed decreased posterior keratometry steep (Ks), keratometry flat (Kf), keratometry average (AvgK), eccentricity (Ecc), an increased corneal apex thickness (CAT), and decreased 3 and 6 mm posterior spherical indices (p < 0.0001 for all of the above). Characteristic features of subclinical FECD, independent of the corneal thickness, can be detected by SS OCT and should be considered during the preoperative assessment of patients with a coexisting cataract. Full article
(This article belongs to the Special Issue New Frontiers in Diagnostics for Cataract Surgery)
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Review

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18 pages, 370 KiB  
Review
Rethinking Elective Cataract Surgery Diagnostics, Assessments, and Tools after the COVID-19 Pandemic Experience and Beyond: Insights from the EUROCOVCAT Group
by Daniele Tognetto, Antoine P. Brézin, Arthur B. Cummings, Boris E. Malyugin, Ozlem Evren Kemer, Isabel Prieto, Robert Rejdak, Miguel A. Teus, Riikka Törnblom, Mario D. Toro, Alex L. Vinciguerra, Rosa Giglio and Chiara De Giacinto
Diagnostics 2020, 10(12), 1035; https://doi.org/10.3390/diagnostics10121035 - 2 Dec 2020
Cited by 37 | Viewed by 5028
Abstract
The progressive deterioration of the visual function in patients on waiting lists for cataract surgery has a negative impact on their quality of life, especially in the elderly population. Patient waiting times for cataract surgeries in many healthcare settings have increased recently due [...] Read more.
The progressive deterioration of the visual function in patients on waiting lists for cataract surgery has a negative impact on their quality of life, especially in the elderly population. Patient waiting times for cataract surgeries in many healthcare settings have increased recently due to the prolonged stop or slowdown of elective cataract surgery as a result of coronavirus disease 19 (COVID-19). The aim of this review is to highlight the impact of such a “de-prioritization” of cataract surgery and to summarize some critical issues and useful hints on how to reorganize cataract pathways, with a special focus on perioperative diagnostic tools during the recovery phase and beyond. The experiences of a group of surgeons originating from nine different countries, named the European COVID-19 Cataract Group (EUROCOVCAT), have been combined with the literature and recommendations from scientific ophthalmic societies and healthcare institutions. Key considerations for elective cataract surgery should include the reduction of the number of unnecessary visits and examinations, adoption of precautionary measures, and implementation of telemedicine instruments. New strategies should be adopted to provide an adequate level of assistance and to guarantee safety conditions. Flexibility will be the watchword and regular updates would be necessary following scientific insights and the development of the pandemic. Full article
(This article belongs to the Special Issue New Frontiers in Diagnostics for Cataract Surgery)

Other

Jump to: Research, Review

11 pages, 5664 KiB  
Case Report
Traumatic Intralenticular Neovascularization in a HLA B27+ Pediatric Patient
by Călin Petru Tătaru, Cătălina Ioana Tătaru, Maria Dudău, Alexandra Moșu, Lăcrămioara Luca, Bosa Maria, Alice Bancu and Paul Filip Curcă
Diagnostics 2021, 11(8), 1493; https://doi.org/10.3390/diagnostics11081493 - 18 Aug 2021
Viewed by 2015
Abstract
(1) Background: Intralenticular tumors are an entity akin to Schrodinger’s cat since, although the human crystalline cells themselves are not known to malignly proliferate, various entities can take the appearance and clinical presentation of a tumor originating in the lens. We present the [...] Read more.
(1) Background: Intralenticular tumors are an entity akin to Schrodinger’s cat since, although the human crystalline cells themselves are not known to malignly proliferate, various entities can take the appearance and clinical presentation of a tumor originating in the lens. We present the peculiar case of an 11-year-old male patient of African descent, HLA B27+, with a previous history of minor ocular trauma and unilateral anterior uveitis a year before which was admitted to our department with total opacification of the crystalline lens in the right eye and lens neovascularization. During surgery, a vascular, white fibrotic mass measuring 0.1–0.2 cm was discovered inside the lens bag and was excised. (2) Methods: Retrospective case review. (3) Results: The histopathological exam of the excised mass revealed an abundant infiltrate consisting of CD68+ foamy macrophages and lymphoplasmacytic elements. CD68 is a pan-macrophage marker associated with an active inflammatory mechanism soliciting macrophages, and tissue activated macrophages are correlated to increased stromal and serum levels of vascular endothelial growth factor, providing an explanation for lens angiogenesis. (4) Conclusions: The diagnosis is of a “masquerade tumor” resulted from an abnormal inflammatory process in connection with previous ocular trauma and possibly the patient’s HLA B27+ status. Full article
(This article belongs to the Special Issue New Frontiers in Diagnostics for Cataract Surgery)
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