Role of Probiotics in Food Fermentation and Their Health Benefits

A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Probiotic Strains and Fermentation".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 5942

Special Issue Editors


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Guest Editor
Escuela de Ingeniería y Ciencias, Food and Biotech Lab, Tecnologico de Monterrey, Ave. General Ramón Corona 2514, Zapopan 45138, Jalisco, México
Interests: cloning; food microbiology; microbial molecular biology; biotechnology; microbiology; PCR; food microbiology and safety; food safety; food science and technology; antimicrobials
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Guest Editor
Laboratorio de Ecofisiología Tecnológica, CERELA-CONICET, San Miguel de Tucumán, y Universidad de San Pablo Tucumán, Av. Solano Vera y Camino a Villa Nougués, San Pablo, Tucumán 4129, Argentina
Interests: food, beverages; tobacco-agrar products; hygiene; food and nutrition-others

Special Issue Information

Dear Colleagues,

In the past, food fermentation was used to preserve foods, enhance shelf life, and improve flavour. Nowadays, fermented foods have attracted scientific interest because they have been associated with many health benefits. These beneficial effects are often attributed to their nutritional and microbial composition. Different microorganisms are used as starters, adjunct cultures, and as probiotics in fermented foods due to the wide range of biomolecules that they produce during fermentation process, including specific health-promoting components. Probiotics are usually defined as live microbial dietary supplements with benefits for the host’s health that consume them in certain amounts. In this regard, fermented foods including probiotics may provide mechanisms to enhance the health status and even prevent and manage chronic diseases related to metabolic syndrome, mental health, immune system, intestinal tract, etc. These mechanisms by which probiotics exert their effects within food fermentation are largely unknown. Therefore, the aim of this Special Issue is to provide a platform for the publication of valuable articles related to the role of probiotics contributing to the food fermentation process and the health-promoting properties.

Original research articles and reviews are both welcome. Research areas may include (but are not limited to) the following:

  • The development of new fermented foods with probiotic properties
  • Identification of biomolecules released by probiotics during fermentation process
  • Evaluation of the effects of probiotic fermented foods (in vitro, in vivo and ex vivo)
  • The interaction between probiotics and other microorganisms during the fermentation process
  • Health benefits of the association of fermented foods and probiotics
  • Innovative fermented food products as a vehicle of probiotics
  • Characterization of functionality of probiotics after the fermentation process using in vitro and in vivo models

Prof. Dr. Tomas García-Cayuela
Dr. Gabriela Zarate
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • probiotic
  • probiotic fermented food, health benefits
  • probiotic functionality
  • food fermentation
  • health-promoting components
  • mechanisms of action of probiotics

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Published Papers (3 papers)

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Research

23 pages, 10973 KiB  
Article
Alleviating Effect of Lactiplantibacillus plantarum NXU0011 Fermented Wolfberry on Ulcerative Colitis in Mice
by Mingxia Nie, Quan Ji, Gang Guo, Haiyan Zhang, Yanhong Wang, Ru Zhai and Lin Pan
Fermentation 2023, 9(11), 971; https://doi.org/10.3390/fermentation9110971 - 14 Nov 2023
Cited by 1 | Viewed by 1392
Abstract
As research into the relationship between the gut microbiome and health continues to evolve, probiotics are garnering increasing interest among consumers. Fermentation is recognized as an efficacious biotechnology for augmenting the nutritional and functional attributes of foods. In this study, the ameliorative effects [...] Read more.
As research into the relationship between the gut microbiome and health continues to evolve, probiotics are garnering increasing interest among consumers. Fermentation is recognized as an efficacious biotechnology for augmenting the nutritional and functional attributes of foods. In this study, the ameliorative effects of Lycium barbarum L. lyophilized powder fermented with Lactiplantibacillus plantarum NXU0011 (LP+Ly) on dextran sodium sulfate (DSS)-induced ulcerative colitis (UC) in mice were investigated employing immunohistochemistry, qRT-PCR, macrogenomics, and metabolomics. The results revealed that LP+Ly intervention significantly ameliorated histopathological inflammation in the ulcerated colon, diminished the expression of inflammatory markers such as IL-6, P-STAT3, and miR-214, and enhanced the diversity of intestinal flora in the mouse model group. Moreover, there was an increase in the abundance of beneficial bacteria, including Lactobacillus, Prevotella, and Akkermansia. Metabolomic analysis indicated that 15 metabolites, including citrulline, D-xylose, and α-ketoisovaleric acid, exhibited significant variations following the LP+Ly intervention. The metabolic pathways that displayed substantial differences included tryptophan biosynthesis, arginine biosynthesis, and amino sugar and nucleotide sugar metabolism. LP+Ly effectively improved the inflammatory state within the intestines by modulating arginine biosynthesis, thus alleviating the impact of UC. Full article
(This article belongs to the Special Issue Role of Probiotics in Food Fermentation and Their Health Benefits)
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11 pages, 631 KiB  
Article
Cheese Fermented with Human-Derived Limosilactobacillus reuteri DSM 17938 and Mushroom Powders: A Novel Psychobiotic Food with Enhanced Bioactivity and Sensory Acceptability
by Marina Jovanović, Petar Vojvodić, Dina Tenji, Nina Tomić, Jovana Nešić, Dragana Mitić-Ćulafić and Jelena Miočinović
Fermentation 2023, 9(8), 745; https://doi.org/10.3390/fermentation9080745 - 10 Aug 2023
Cited by 1 | Viewed by 2128
Abstract
Fermented foods containing psychobiotics are of growing interest among food scientists. Human-derived Limosilactobacillus reuteri DSM 17938, a gut symbiont and potential psychobiotic strain, has been shown to exhibit the following health benefits: anti-inflammation and GABA-production capacity, as well as modulation of pathogen and [...] Read more.
Fermented foods containing psychobiotics are of growing interest among food scientists. Human-derived Limosilactobacillus reuteri DSM 17938, a gut symbiont and potential psychobiotic strain, has been shown to exhibit the following health benefits: anti-inflammation and GABA-production capacity, as well as modulation of pathogen and cancer cell growth. The aim of this research was to develop an acid-coagulated fresh soft quark-type cheese, fermented with L. reuteri DSM 17938, with enhanced bioactivity, sensory acceptability, and overall likeability. Psychobiotic-containing cheeses represent the food of a new generation, so it is of great importance to gain the trust of the consumers. To develop a familiar taste, cheese samples were enriched with mushroom powders of Agaricus bisporus and Pleurotus ostreatus. A high abundance of lactic acid bacteria was maintained in all cheese samples (>log 7.64 CFU/mL), while cheese extracts exhibited cytotoxicity to colon cancer cell line HCT116 (up to 30.96%) in vitro. Additionally, cheese samples provided a favorable medium for the growth of the probiotic Escherichia coli Nissle 1917 (>log 7.11 CFU/mL). Sensory evaluation revealed high scores for all samples (up to 97.21% of maximum overall quality). The survey conducted in this study offered insights into consumer willingness to try products containing psychobiotics. This study demonstrates the potential for the successful development of fermented food products with L. reuteri DSM 17938, which exhibits all the desired traits that consumers may receive well. Further research is required to explore the potential health benefits of these innovative food products. Full article
(This article belongs to the Special Issue Role of Probiotics in Food Fermentation and Their Health Benefits)
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14 pages, 4512 KiB  
Article
Exopolysaccharide from Lactiplantibacillus plantarum YT013 and Its Apoptotic Activity on Gastric Cancer AGS Cells
by Rentao Zhang, Zhongkun Zhou, Yunhao Ma, Kangjia Du, Mengze Sun, Hao Zhang, Hongyuan Tu, Xinrong Jiang, Juan Lu, Lixue Tu, Yuqing Niu and Peng Chen
Fermentation 2023, 9(6), 539; https://doi.org/10.3390/fermentation9060539 - 31 May 2023
Cited by 2 | Viewed by 1876
Abstract
Cancer is a significant health burden in the world. Natural product drugs have received widespread attention because of their safety and effectiveness, stable effects and fewer side effects. Some studies have demonstrated that exopolysaccharide (EPS) from lactic acid bacteria (LAB) can inhibit the [...] Read more.
Cancer is a significant health burden in the world. Natural product drugs have received widespread attention because of their safety and effectiveness, stable effects and fewer side effects. Some studies have demonstrated that exopolysaccharide (EPS) from lactic acid bacteria (LAB) can inhibit the growth of many types of cancer cells. In this work, the effects of the EPS from Lactiplantibacillus plantarum YT013 on gastric cancer cells were investigated. Its cytotoxicity was evaluated by MTT assay; at the concentration of 1000 μg/mL, the most significant inhibitory effect occurred in AGS cells, followed by SGC-7901, PANC-1 and HCT116, and less inhibited in HepG2 cells. Cell cycle results showed that EPS prevented AGS cells from transitioning from the S phase to the G2/M phase. In addition, the results of flow cytometry showed that EPS promoted apoptosis in a concentration-dependent manner. Western blotting also indicated that EPS might lead to apoptosis via the endogenous mitochondrial apoptotic pathway. The safety of lyophilized powder, cell-free culture supernatant and EPS from Lactiplantibacillus plantarum YT013 were evaluated by observing tissue organs through H&E staining, and the results showed that the components were safe and effective and could provide a basis for the development of natural anticancer active drugs. Full article
(This article belongs to the Special Issue Role of Probiotics in Food Fermentation and Their Health Benefits)
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