Genetic and Molecular Mechanisms of Antimicrobial Resistance in Bacteria
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Microbial Genetics and Genomics".
Deadline for manuscript submissions: 15 December 2024 | Viewed by 1142
Special Issue Editor
Special Issue Information
Dear Colleagues,
Pathogens present an ongoing threat to public health, and the emergence of antimicrobial resistance in these organisms exacerbates this issue. Bacteria, such as pathogenic Escherichia coli, Klebsiella pneumoniae, Shigella, Salmonella, Staphylococcus aureus, Pseudomonas aeruginosa, Vibrio parahaemolyticus, Campylobacter coli, etc., continuously evolve novel mechanisms of resistance to survive antibiotic pressure. The acquisition of resistance genes through mobile genetic elements like plasmids and transposons serves as the primary driver behind antimicrobial resistance. Moreover, pathogens can undergo adaptive regulation and gene mutations to counteract antibiotic pressure. A comprehensive understanding of the molecular mechanisms underlying antimicrobial resistance phenotypes is crucial for identifying potential targets aimed at controlling antimicrobial-resistant pathogens. This Special Issue aims to enhance our comprehension regarding recent advancements in the research on genetic and molecular mechanisms associated with antimicrobial resistance. Specifically welcome are papers focusing on antimicrobial resistance genes; regulatory mechanisms related to these genes; adaptive changes in pathogens in response to antimicrobial pressure; and other relevant topics.
Dr. Biao Tang
Guest Editor
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Keywords
- antimicrobial resistance
- genome
- horizontal gene transfer
- resistance mechanism
- acquired resistance gene
- pathogens
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