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Accelerated Aging and Chronic Diseases Across the Life-Course
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Accelerated Aging and Chronic Diseases Across the Life-Course

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Aging".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 6661

Special Issue Editors

Dr. Jud Janak

E-Mail Website
Guest Editor
Bexar Data Limited Company, San Antonio, TX 78210, USA
Interests: life-course epidemiology; military and veterans’ health; combat casualty care; injury epidemiology; preventable death; biostatistics
Special Issues, Collections and Topics in MDPI journals
Dr. Jeffrey T. Howard

E-Mail Website
Guest Editor
Department of Kinesiology, Health and Nutrition, University of Texas at San Antonio, San Antonio, TX 78249, USA
Interests: traumatic injury and chronic disease; epidemiology; military/veterans’ health; biodemography and aging; health disparities; mortality; environmental disaster and climate change health impacts; medical/physiologicalmonitoring; statistical method
Dr. Kevin Heffernan

E-Mail Website
Guest Editor
Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA
Interests: vascular aging and chronic disease; cardiovascular exercise physiology; health disparities; medical/physiological monitoring

Special Issue Information

Dear Colleagues,

Despite dramatic advances in medical care and public health over the last century, many countries report that life expectancy has stabilized or in some instances decreased. In the 21st century, this burden is often driven by early deaths from working-age adults of lower socioeconomic status caused by an increase in homicides, suicides, and drug overdoses. Equally concerning is the alarming increase in chronic diseases and disability across the globe associated with decreased quality of life, and a host of economic and societal consequences. The associations between health behaviors (e.g., sleep, diet, physical activity), environmental factors (e.g., access to quality healthcare, air pollution, environmental disasters, physical and psychological trauma), and accelerated aging manifesting as disability, chronic disease, injury, and mortality remains unclear. To address these gaps, the aim of this Special Issue is to elucidate the burden, environmental factors, genetic factors, and underlying pathophysiologic mechanisms of accelerated aging. 

Dr. Jud Janak
Dr. Jeffrey T. Howard
Dr. Kevin Heffernan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • accelerated aging
  • life course
  • disability
  • chronic disease
  • injury
  • mortality

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Published Papers (3 papers)

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Research

9 pages, 481 KiB  
Article
Factors Associated with Passive Sedentary Behavior among Community-Dwelling Older Women with and without Knee Osteoarthritis: The Otassha Study
by Naoki Deguchi, Narumi Kojima, Yosuke Osuka and Hiroyuki Sasai
Int. J. Environ. Res. Public Health 2022, 19(21), 13765; https://doi.org/10.3390/ijerph192113765 - 23 Oct 2022
Cited by 5 | Viewed by 2173
Abstract
Passive sedentary behavior (SB) may lead to adverse health outcomes; however, it remains unclear whether the factors relevant to passive SB differ between older adults with and without knee osteoarthritis (KOA). This cross-sectional study examined factors associated with passive SB among 688 community-dwelling [...] Read more.
Passive sedentary behavior (SB) may lead to adverse health outcomes; however, it remains unclear whether the factors relevant to passive SB differ between older adults with and without knee osteoarthritis (KOA). This cross-sectional study examined factors associated with passive SB among 688 community-dwelling older women with (n = 128) and without (n = 560) KOA. Passive SB (min/day) was assessed using the Japanese-translated version of the Measure of Older Adults’ Sedentary Time questionnaire. Demographic, lifestyle, and psychosocial factors; pain; and physical performance were evaluated in multiple regression models with an interaction term concerning SB between the two groups. The mean (SD) total SB for those without and with KOA was 490.4 (200.9) min/day and 487.4 (185.8) min/day, respectively, and the majority of SB was passive, with no difference between groups. Passive SB was associated with an obese status and less time spent in group activities. However, no KOA-specific SB factors were identified. Therefore, effective interventions to promote social participation and weight loss, especially for individuals with obesity, may reduce passive SB, regardless of KOA. Longitudinal studies are warranted to identify causal relationships. Full article
(This article belongs to the Special Issue Accelerated Aging and Chronic Diseases Across the Life-Course)
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15 pages, 1056 KiB  
Article
Emotion Recognition in a Health Continuum: Comparison of Healthy Adults of Advancing Age, Community Dwelling Adults Bearing Vascular Risk Factors and People Diagnosed with Mild Cognitive Impairment
by Glykeria Tsentidou, Despina Moraitou and Magdalini Tsolaki
Int. J. Environ. Res. Public Health 2022, 19(20), 13366; https://doi.org/10.3390/ijerph192013366 - 16 Oct 2022
Cited by 2 | Viewed by 2021
Abstract
The identification of basic emotions plays an important role in social relationships and behaviors linked to survival. In neurodegenerative conditions such as Alzheimer’s disease (AD), the ability to recognize emotions may already be impaired at early stages of the disease, such as the [...] Read more.
The identification of basic emotions plays an important role in social relationships and behaviors linked to survival. In neurodegenerative conditions such as Alzheimer’s disease (AD), the ability to recognize emotions may already be impaired at early stages of the disease, such as the stage of Mild Cognitive Impairment (MCI). However, as regards vascular pathologies related to cognitive impairment, very little is known about emotion recognition in people bearing vascular risk factors (VRF). Therefore, the aim of the present study was to examine emotion recognition ability in the health continuum “healthy advancing age—advancing age with VRF—MCI”. The sample consisted of 106 adults divided in three diagnostic groups; 43 adults with MCI, 41 adults bearing one or more VRF, and 22 healthy controls of advancing age (HC). Since HC were more educated and younger than the other two groups, the age-group and level of educational were taken into account in the statistical analyses. A dynamic visual test was administered to examine recognition of basic emotions and emotionally neutral conditions. The results showed only a significant diagnostic group x educational level interaction as regards total emotion recognition ability, F (4, 28.910) = 4.117 p = 0.004 η2 = 0.166. High educational level seems to contribute to a high-level-emotion-recognition-performance both in healthy adults of advancing age and in adults bearing vascular risk factors. Medium educational level appears to play the same role only in healthy adults. Neither educational level can help MCI people to enhance their significantly lower emotion recognition ability. Full article
(This article belongs to the Special Issue Accelerated Aging and Chronic Diseases Across the Life-Course)
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19 pages, 1214 KiB  
Article
Stable Gender Gap and Similar Gender Trend in Chronic Morbidities between 1997–2015 in Adult Canary Population
by Luis Miguel Bello-Lujan, Jose Antonio Serrano-Sanchez and Juan Jose Gonzalez-Henriquez
Int. J. Environ. Res. Public Health 2022, 19(15), 9404; https://doi.org/10.3390/ijerph19159404 - 31 Jul 2022
Cited by 2 | Viewed by 1901
Abstract
There is little information about the trend of the gender gap in chronic morbidities and whether the trend of expansion occurs equally in the age and gender groups. The objectives were to examine the consistency and stability of the gender gap in the [...] Read more.
There is little information about the trend of the gender gap in chronic morbidities and whether the trend of expansion occurs equally in the age and gender groups. The objectives were to examine the consistency and stability of the gender gap in the main self-reported chronic morbidities in the general population, and, likewise, to analyze the trend of major chronic morbidities between 1997 and 2015 in men and women across age groups. The data were extracted from the Canary Health Survey, which uses a probabilistic sampling in the population >16 years of age, for the years 1997 (n = 2167), 2004 (n = 4304), 2009 (n = 4542), and 2015 (n = 4560). The data for the twelve most frequent chronic morbidities were analyzed using logistic regression, estimating the annual change ratio between 1997 and 2015, adjusting for age and educational level. The interaction of age with the period (1997–2015) was examined to analyze the rate of change for each morbidity in the age groups. Musculoskeletal diseases, headaches, anxiety and depression, and peripheral vascular diseases showed a stable gender gap across observed years. High cholesterol and high blood pressure tended to a gap reduction, while heart disease, diabetes, and respiratory disease did not show a significant gender gap along the period. The trend of the main chronic morbidities increased similarly in men and women in all age groups, but significantly in women older than 60 years and in men older than 45 years. Aging explained a substantial part of the trend of increasing prevalence of the main chronic morbidities, but not totally. Factors other than age and education are driving the increase in chronic morbidity in older age groups. Full article
(This article belongs to the Special Issue Accelerated Aging and Chronic Diseases Across the Life-Course)
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