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Exploring New Field in Hydrocolloids Research and Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Physical Chemistry and Chemical Physics".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 628

Special Issue Editors


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Guest Editor
Physical and Colloidal Chemistry Department, Faculty of Pharmacy, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
Interests: biomaterials (collagen drug delivery systems); rheology; cosmeceuticals; drug systems formulation and technological processes optimization; response surface methodology; Taguchi design
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Physical and Colloidal Chemistry Department, Faculty of Pharmacy, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
Interests: targeted drug delivery; nanoparticulate systems; solubility enhancement techniques; biotechnology; topical/transdermal drug delivery
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Physical and Colloidal Chemistry Department, Faculty of Pharmacy, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
Interests: quality by design (QbD); analytical quality by design (AQbD); drug systems formulation (Chitosan); surfaces’ characteristics (wettability/hidrophilicity/hidrophobicity—pharmaceutical powders)
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue of the journal explores the complex world of hydrocolloids, highlighting important and cutting-edge research, innovative applications, and the latest technological advancements. Hydrocolloids are known for their capacity to modify the viscosity of aqueous solutions, playing a very important role in a wide range of sectors, including pharmaceuticals, medical devices, cosmetics, industry, food, and agriculture, with a particular emphasis on their molecular aspects and interactions. This Special Issue highlights recent advancements in the synthesis, characterization, and functionalization of hydrocolloids to improve their efficacy and compatibility in different applications.

In medical and biomedical applications, hydrocolloids are explored for their potential in drug delivery systems, tissue engineering, and wound healing applications due to their biocompatibility and gel-forming capabilities. This Special Issue emphasizes the molecular tailoring of hydrocolloids to develop stimuli-responsive systems that can offer targeted and controlled release of drugs, thus enhancing therapeutic outcomes.

Pharmaceutical applications use hydrocolloids to formulate stable and effective delivery vehicles, particularly focusing on their role in encapsulating special molecules like proteins and enzymes, and thereby stabilizing them against environmental stressors.

Industry-related applications cover the utilization of hydrocolloids in enhancing the texture and stability of food products, with molecular insights into their interactions with other food components leading to improved food quality and safety.

The Special Issue integrates molecular-level investigations with practical applications, providing a detailed look at how the manipulation of molecular structures of hydrocolloids can lead to significant advancements in technology and product development.

Also, this issue provides insights into the mechanisms of action, functional characteristics, and sustainable sources of hydrocolloids through a collection of in-depth research articles, and reviews.

We propose some keywords reflecting the multifunctionality of hydrocolloids in medical and pharmaceutical applications, underlining their significance in advancing healthcare technologies and treatments.

Prof. Dr. Mihaela Violeta Ghica
Prof. Dr. Cristina Elena Dinu-Pirvu
Prof. Dr. Lacramioara Popa
Guest Editors

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Keywords

  • drug delivery systems
  • controlled-release
  • targeted delivery
  • wound healing
  • tissue engineering
  • bioadhesive agents
  • transdermal patches
  • mucoadhesive hydrogels
  • ophthalmic preparations
  • oral disintegrating films
  • gastroretentive systems
  • rheology modifiers
  • textural characteristics
  • stabilizing agents
  • encapsulation for protection and stability (drugs, probiotics and bioactive compounds)
  • 3D bioprinting
  • nutraceutical delivery

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Published Papers (1 paper)

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Research

18 pages, 4901 KiB  
Article
Development and Analysis of Bilayer Foamed Oleogels Stabilized with Ecogel™: Exploring the Role of Tween 80 in Modifying Physicochemical Properties
by Sonia Kudłacik-Kramarczyk, Anna Drabczyk, Alicja Przybyłowicz, Weronika Kieres and Marcel Krzan
Int. J. Mol. Sci. 2024, 25(23), 12632; https://doi.org/10.3390/ijms252312632 - 25 Nov 2024
Viewed by 342
Abstract
Oleogels are structured materials formed by immobilizing oil within a polymer network. This study aimed to synthesize bilayer foamed oleogels using Ecogel™ as an emulsifier—a natural gelling and emulsifying agent commonly used to stabilize emulsions. Ecogel™ is multifunctional, particularly in cosmetic formulations, where [...] Read more.
Oleogels are structured materials formed by immobilizing oil within a polymer network. This study aimed to synthesize bilayer foamed oleogels using Ecogel™ as an emulsifier—a natural gelling and emulsifying agent commonly used to stabilize emulsions. Ecogel™ is multifunctional, particularly in cosmetic formulations, where it aids in creating lightweight cream gels with a cooling effect. However, the specific goal of this study was to investigate the physicochemical properties of oleogels formed with Ecogel™, Tween 80, gelatin, and glycerin. The combination of these ingredients has not been studied before, particularly in the context of bilayer foamed oleogels. The biphasic nature of the resulting materials was explored, consisting of a uniform lower phase and a foamed upper layer. Several analytical techniques were employed, including FT-IR spectrophotometric analysis, moisture content evaluation, surface wettability measurements, microscopic imaging, and rheological studies, in addition to surface energy determination. The results demonstrated that the addition of Tween 80 significantly improved the stability and rigidity of the oleogels. Furthermore, storage at reduced temperatures after synthesis enhanced the material’s stabilizing properties. These materials also showed an affinity for interacting with non-polar compounds, indicating potential applications in skincare, especially for interaction with skin lipids. Full article
(This article belongs to the Special Issue Exploring New Field in Hydrocolloids Research and Applications)
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