Biomarkers for Cardiometabolic Risk: Pathophysiology, Impact, Advances and Challenges
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 1549
Special Issue Editors
Interests: medicine; biochemistry; genetics and molecular biology cardiovascular disease
Special Issues, Collections and Topics in MDPI journals
Interests: metabolic disease; organ pathophysiology; cardiovascular disease; metabolomic ad lipidomic technology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiometabolic (CM) diseases remain the leading cause of morbidity and mortality worldwide, suggesting the importance of new, reliable tools to evaluate their occurrence. In reality, a number of different biomarkers continue to be proposed and tested, giving further insights into the pathophysiological mechanisms underlying cardiometabolic conditions. However, generally, they give only a moderate increase in the predictive value over the use of tools based on classic and consolidated risk factors included in traditional risk scores. The simultaneous measurement of multiple biomarker parameters (the multimarker approach) seems to add a substantial advantage, which can provide an accurate prediction for specific patients and drive targeted preventive therapy.
We invite investigators to contribute either original research or review articles to this Special Issue; the topics of interest include, but are not limited to:
- The role of different biomarkers, including established CM biomarkers, as well as emerging biomarkers identified through omics technologies (e.g., the combination of genomics, transcriptomics, epigenetics, and proteomics) used alone or in multiple biomarker combinations to improve our CM pathophysiological knowledge.
- In addition to the pathophysiological significance, we are interested in the technical aspects still challenging the analysis of molecular biomarkers, as well as translational issues.
Dr. Cristina Vassalle
Dr. Melania Gaggini
Guest Editors
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Keywords
- biomarker
- cardiovascular risk
- cardiometabolic disease
- omics technologies
- genomics
- transcriptomics
- epigenetics
- proteomics
- translational medicine
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