Cell Metabolism: Its Physiology, Dysfunction, and Related Metabolic Complications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 3409
Special Issue Editor
Interests: DNA methylation; TET proteins; hematopoietic stem cells; hematopoiesis; leukemia; cancer epigenetics; cancer therapy; drug screen; metabolic diseases; obesity; diabetes; biosensor; signaling and gene expression
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolism, the cornerstone of life, is finely orchestrated by the complex interplay among cells within specialized tissues, notably adipocytes, muscle cells, and hepatocytes. Adipocytes govern systemic energy and glucose homeostasis, thermogenesis, and hormone secretion. Muscle cells, with their high energy demands, also play a central role in glucose uptake and utilization. Dysfunction within these cells disrupts the metabolic balance, contributing to various complications, including insulin resistance, obesity, diabetes, and cardiovascular diseases. Additionally, hepatocytes, the metabolic powerhouses, also dictate glucose and lipid metabolism and detoxification, and they are the central players in diabetes, fatty liver disease, hepatic inflammation and fibrosis, and liver cancers. This Special Issue aims to explore the intricate molecular events and mechanisms that underlie both normal and aberrant cellular metabolism, along with the associated metabolic disorders.
We invite submissions of original research articles, reviews, and clinical studies that address, but are not limited to, the following areas:
- Molecular insights into adipocyte differentiation and function;
- Adipose tissue inflammation and metabolic dysfunction;
- Role of adipokines in metabolism;
- Adipose tissue remodeling in health and disease;
- Hepatic glucose and lipid metabolism;
- Crosstalk among liver, muscle, and adipose tissues in metabolic regulation;
- Genetic and epigenetic regulation of metabolism;
- Obesity and diabetes: mechanisms, complications, and therapeutic interventions;
- Steatosis, hepatitis, and cirrhosis: underlying mechanisms and therapeutic targets;
- Liver cancers: pathology and therapeutic strategies;
- Innovative therapeutic approaches to treat metabolic diseases.
We look forward to receiving your contributions.
Dr. Myunggon Ko
Guest Editor
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Keywords
- cell metabolism
- adipocytes
- muscle cells
- hepatocytes
- insulin resistance
- inflammation
- obesity
- diabetes
- hepatic disorders
- cardiovascular diseases
- cancers
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