Natural Antioxidants in Human Health and Disease, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 2205
Special Issue Editor
Interests: metabolic disorders; cancer; inflammation; oxidative stress; natural compounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative stress, defined as an overproduction of reactive oxygen (ROS) and nitrogen species (RNS) in cells and tissues, plays a pathogenic role in the development of several inflammatory chronic diseases, especially in the case of atherosclerosis, hypertension, obesity, diabetes, metabolic syndrome, and cancer. The increase in ROS and RNS can cause oxidative damage and tissue dysfunction due to structural damage to macromolecules, giving rise to senescent and degenerative lesions in cells. Natural compounds are a source of exogenous antioxidants possibly useful in the management of these pathologies. They have long been considered antioxidant molecules, and most of their benefits have been related to their free radical scavenging properties. Recent findings have shown that these compounds have multiple mechanisms of action in the treatment or prevention of oxidative disorders. Natural antioxidants could interact in humans with pleiotropic effects on a variety of tissues involved in stress response pathways. However, their diversity and chemical complexity mean that much remains to be understood about the mechanisms by which these compounds influence health.
This Special Issue is a collection of research and review articles on the preclinical and clinical benefits of natural antioxidants, with special interest in human health and disease. The aim of this Special Issue is to collect literature that reflects the actual state of the art and increase our knowledge of natural antioxidants and the mechanism of action in their physiological and pathophysiological role. Further, their bioavailability and biotransformation events should be considered to identify the most likely final effectors in cells and tissues.
Leading by Dr. María Herranz-López and assisting by our Topical Advisory Panel Member Dr. Xiaxia Di (NIVA—Norsk Institutt for Vannforskning/Norwegian Institute for Water Research), we cordially invite researchers from all around the world to contribute by submitting original research articles, long and mini review papers, short notes, and opinions in accordance with their expertise.
Dr. María Herranz-López
Guest Editor
Manuscript Submission Information
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Keywords
- ROS
- oxidative disorders
- molecular pathways
- inflammation
- biotransformation
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