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Plant-Derived Food Products in the Prevention of Chronic Non-Communicable Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 20 March 2025 | Viewed by 3627

Special Issue Editors


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Guest Editor
Department of Human Nutrition and Dietetics, University of Agriculture in Krakow, Al. Mickiewicza 21, 31-120 Krakow, Poland
Interests: health-promoting properties of food; chronic non-communicable diseases; assessment of human nutrition and nutritional status
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Human Nutrition and Dietetics, University of Agriculture in Krakow, Al. Mickiewicza 21, 31-120 Krakow, Poland
Interests: plant-based foods; antioxidant activity; glycaemic index; antitumor and antidiabetic activity of plant-based food; toxins in food
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Human Nutrition and Dietetics, University of Agriculture in Krakow, Balicka 122, 30-149 Krakow, Poland
Interests: human nutrition; dietetics; brassica vegetables; nutrients; non-essential nutrients; vitamin C; β-carotene; total polyphenols; chemical contaminants; antioxidant activity; nutritive value; starch digestibility; vegetables; iodine absorption; chemical analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

As a potential source of antioxidant compounds in the daily diet, plant foods (fruits and vegetables) are usually mentioned first. Oxidative stress and the production of harmful reactive oxygen species are caused by the lack of a physiological balance between free radicals produced in the body and their natural method of inactivation. The antioxidative substances in plants can help protect the human system from diseases resulting from a weakened immune system. The body’s imbalance is now considered a major cause of aging and the development of chronic non-communicable diseases (diabetes, cancer, cardiovascular diseases, and neurological diseases including Parkinson’s and Alzheimer’s). Some evidence suggests that certain plant molecules may have much more potent antioxidant properties than the well-known antioxidant vitamins, but these findings are still awaited. This Special Issue aims to review the potential of common and uncommon plants and plant foods as potential sources of valuable antioxidants in the human diet for the effective maintenance of human well-being and protection against the development of some diseases.

Since IJMS is a journal of molecular science, we focus on plant bioactive compounds in plant foods and plant-derived foods, such as phenolic compounds, flavonoids, anthocyanidins, flavans, tannins, etc.

We welcome comments and research on the chemical composition of these bioactive compounds and their mechanisms of action in human disease and health.

Prof. Dr. Teresa Leszczyńska
Prof. Dr. Barbara Borczak
Prof. Dr. Joanna Kapusta-Duch
Guest Editors

Manuscript Submission Information

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Keywords

  • plant foods
  • plant-derived foods
  • oxidative stress
  • bioactive compounds
  • antioxidative substances
  • chronic non-communicable diseases

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Published Papers (3 papers)

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Research

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24 pages, 1775 KiB  
Article
Potential Antidiabetic, Antioxidative and Antiproliferative Properties of Functional Wheat Flour Muffins Enriched with White Clover Flowers (Trifolium repens L.)
by Barbara Borczak, Agnieszka Szewczyk, Dominik Domagała, Joanna Kapusta-Duch, Teresa Leszczyńska, Marta Kotuła and Daniela Grulova
Int. J. Mol. Sci. 2024, 25(18), 9909; https://doi.org/10.3390/ijms25189909 - 13 Sep 2024
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Abstract
The aim of the study was to evaluate the functional properties of muffins fortified with white clover flowers (Trifolium repens L.), which were added to the dough in the following amounts: (i) 0% (control); (ii) 2.5%; (iii [...] Read more.
The aim of the study was to evaluate the functional properties of muffins fortified with white clover flowers (Trifolium repens L.), which were added to the dough in the following amounts: (i) 0% (control); (ii) 2.5%; (iii) 5.5%; (iv) 7.5%; and (v) 10%. The organoleptic properties were assessed by a panel of consumers. Additionally, the following parameters were also tested: basic chemical composition, total polyphenols, the antioxidant activity together with antiproliferative effects on the A375 melanoma cell line, starch nutritional fractions and the in vitro glycemic index. As a result, replacing wheat flour with white clover flour significantly affected the color, aroma and taste of the muffins. The content of proteins, fats, total ash, dietary fiber, resistant starch (RS), slowly digestible starch (SDS),total polyphenols and antioxidant activity increased statistically significantly with the elevated amount of white clover flour added to the dough. At the same time, the content of free glucose (FG), rapidly available glucose (RAG) and rapidly digestible starch (RDS), the value of the in vitro glycemic index and the viability of melanoma cancer cells decreased significantly. The muffins enriched with white clover flowers might constitute an interesting proposition and extension of the existing assortment of confectionery products. Full article
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Review

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24 pages, 1738 KiB  
Review
The Other Side of the Perfect Cup: Coffee-Derived Non-Polyphenols and Their Roles in Mitigating Factors Affecting the Pathogenesis of Type 2 Diabetes
by Alexis Ramerth, Brooke Chapple, Jeremiah Winter and William Moore
Int. J. Mol. Sci. 2024, 25(16), 8966; https://doi.org/10.3390/ijms25168966 - 17 Aug 2024
Viewed by 1072
Abstract
The global prevalence of type 2 diabetes (T2D) is 10.5% among adults in the age range of 20–79 years. The primary marker of T2D is persistent fasting hyperglycemia, resulting from insulin resistance and β-cell dysfunction. Multiple factors can promote the development of T2D, [...] Read more.
The global prevalence of type 2 diabetes (T2D) is 10.5% among adults in the age range of 20–79 years. The primary marker of T2D is persistent fasting hyperglycemia, resulting from insulin resistance and β-cell dysfunction. Multiple factors can promote the development of T2D, including obesity, inflammation, and oxidative stress. In contrast, dietary choices have been shown to prevent the onset of T2D. Oatmeal, lean proteins, fruits, and non-starchy vegetables have all been reported to decrease the likelihood of T2D onset. One of the most widely consumed beverages in the world, coffee, has also demonstrated an impressive ability to reduce T2D risk. Coffee contains a diverse array of bioactive molecules. The antidiabetic effects of coffee-derived polyphenols have been thoroughly described and recently reviewed; however, several non-polyphenolic molecules are less prominent but still elicit potent physiological actions. This review summarizes the effects of select coffee-derived non-polyphenols on various aspects of T2D pathogenesis. Full article
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27 pages, 1449 KiB  
Review
Can Isoflavone-Rich Legume Plants Be Useful in the Chemoprevention of Hormone-Dependent Cancers?—A Systematic Review
by Wojciech Paździora, Paweł Paśko, Karolina Grabowska and Agnieszka Galanty
Int. J. Mol. Sci. 2024, 25(13), 7389; https://doi.org/10.3390/ijms25137389 - 5 Jul 2024
Viewed by 1168
Abstract
Plants from the Fabaceae family are widely distributed around the world, especially in Europe, Asia and North America. They are a rich source of isoflavones, compounds with estrogen-like activity, which are suspected of having a chemopreventive effect against hormone-dependent cancers. Following the PRISMA [...] Read more.
Plants from the Fabaceae family are widely distributed around the world, especially in Europe, Asia and North America. They are a rich source of isoflavones, compounds with estrogen-like activity, which are suspected of having a chemopreventive effect against hormone-dependent cancers. Following the PRISMA guidelines, we conducted a systematic review aimed at assessing the impact of Fabaceae plant extracts on hormone-dependent cancer cells and the content of active compounds in plant raw materials. We analyzed the results of 63 articles from in vitro and in vivo studies describing the effect of plant extracts containing isoflavones on cancer cells, along with their anti-inflammatory and antioxidant potential. In the process, we determined the research limitations and future research directions. The collected results indicate the plant species with potentially high contents of phytoestrogens and anti-inflammatory, antioxidant and cytotoxic properties. They point to the potential use of plants in the diet as a source of compounds offering cancer prevention. Full article
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