G Protein-Coupled Receptor Drug Discovery: Recent Advances and Future Perspectives
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 740
Special Issue Editors
Interests: GPCR medicinal chemistry; innovative drug discovery
Special Issues, Collections and Topics in MDPI journals
Interests: drug discovery; drug design; antiviral; HIV-1/AIDS
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
As a family of widely distributed and multifunctional receptors on the cell membrane, G Protein-Coupled Receptors (GPCRs) are not only involved in the regulation of almost all the basic processes of life activities, from neurotransmission to immune response, from hormone secretion to cell proliferation, but have also become one of the most important families of drug targets in modern drug discovery and development. The aim of this Special Issue is to explore the potential of GPCRs as drug targets to analyze their structural and functional mechanisms, to share innovative drug design strategies, and to evaluate the preclinical and clinical results of new drugs.
In this Special Issue, original research articles and reviews are welcome to be submitted. Research areas may include, but are not limited to, the following:
- New discoveries in GPCR structure and function;
- GPCR-targeted drug design, synthesis, and optimization;
- In-depth analysis of the relationship between GPCR signaling mechanisms and diseases;
- GPCR-targeted drug screening platforms and technological innovations;
- Preclinical evaluation and clinical trial progress of GPCR drugs;
- Prospects and challenges of GPCR drugs in the treatment of specific/rare diseases.
Prof. Dr. Boshi Huang
Prof. Dr. Dongwei Kang
Guest Editors
Manuscript Submission Information
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Keywords
- GPCR drug discovery
- GPCR therapeutics
- drug design and synthesis
- structural biology
- preclinical evaluation
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