Cellular and Molecular Biology of Cilia: Structure, Function, and Beyond
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 1606
Special Issue Editor
Interests: motile cilia; airway biology; epithelial ion transport; cell signaling; intracellular Cl-signaling; cell volume regulation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cilia are hair-like projections with axoneme. The non-motile primary cilia regulate cellular signals in development and homeostasis. The motile cilia, which are driven by dyneins in the axoneme, regulate the movements of unicellular organisms and the transport in the epithelial surface. Eukaryotic cells possess one or two cilia, such as “Chlamydomonas”, or many cilia, such as “Paramecium”. In vertebrates, multiciliated cells cover the epithelial surfaces of specialized organs. Their cilia beat in a coordinated and polarized manner to produce unidirectional fluid flow, which plays critical roles in Left-Right determination in embryo, circulation of cerebrospinal fluid in the brain, mucociliary clearance in airways, and egg transport in oviducts. Dysfunction of cilia causes a variety of diseases, called “ciliopathy”. Recent research in the cellular and molecular biology of cilia increases our knowledge. In this issue, we provide the topics in the recent cilia research.
Prof. Dr. Takashi Nakahari
Guest Editor
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Keywords
- cilia
- ciliopathy
- airway biology
- infertility
- brain ventricle
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