Unraveling the Molecular Impact of Sex and Gender on Disease Progression: An In-Depth Exploration
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 1743
Special Issue Editors
Interests: kidney pathology; dialysis; vascular pathology; molecular medicine; predictive medicine; personalized medicine; inflammation; ncRNAs; organs-on-chip; artificial intelligence
Special Issues, Collections and Topics in MDPI journals
Interests: molecular medicine; predictive medicine; personalized medicine; inflammation; ncRNAs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is known that women exhibit a lower susceptibility to certain diseases, particularly chronic conditions such as cardiovascular or kidney diseases, and their progression tends to be slower. While it is important to differentiate between sex and gender as separate concepts, their influence is often linked. However, the underlying mechanisms explaining these differences are not yet fully understood. One potential explanation is related with the differential responsiveness to Ang2, where sex-associated variations in the components and regulation of the renin–angiotensin system (RAS) have been observed. Notably, several cardiovascular studies have indicated that women exhibit reduced sensitivity to angiotensin-converting enzyme (ACE) inhibition compared to men. In addition, it is crucial to acknowledge that women often assume the role of primary caregivers and may be more inclined to delay prevention and treatment for chronic conditions.
Consequently, this Special Issue aims to provide molecular-level insights into understanding and addressing the disparities in disease susceptibility, progression and treatment response. We welcome research submissions at the molecular level, including comprehensive reviews and original research papers. We encourage researchers to present practical insights, novel methodologies and evidence-based recommendations that can guide clinical practice and policy development. In line with the journal’s mission—IJMS is a journal of molecular science—pure clinical studies will not be suitable but clinical submissions with biomolecular experiments are welcomed.
Dr. Miguel Hueso
Dr. Estanislao Navarro
Guest Editors
Manuscript Submission Information
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Keywords
- personalized medicine
- sex
- gender
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